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The map label for this gene is 150400491

Identifier: 150400491

GI number: 150400491

Start: 60356

End: 61279

Strand: Reverse

Name: 150400491

Synonym: Maeo_0053

Alternate gene names: NA

Gene position: 61279-60356 (Counterclockwise)

Preceding gene: 150400492

Following gene: 150400490

Centisome position: 3.9

GC content: 23.81

Gene sequence:

>924_bases
ATGATGACAGGTAACACTTCGTTTATACCATTATACATTAAATTAGATAATTTTAAGGTTTGTATTTTTGGATTTGGCGA
AGTTGGGCAAAGACGATTTAATAAAATATTAAAAGGAGCTCCTAAAAAAATAACTATCTACGATAAATGCAAACACATAG
GGGTACAAAATACTTCGTCTTTTGAATCATCTCAAACTTTTCCAGAGGGAAAGTTTTACGACTGTAAAAATGGCAAAGCC
ATTTTGAAGAATCAAAGAGCAGGAAATCAAAGATTTGACACCATTAATTTAAATAATACAAAAGATATTAAAAATATTAA
CTTCATACAACAAGACATAAATAATTTATCAAATGAAGAATTAGAAAATATTATAAAAAATTATGATATTATTATTACGG
CAATTGATGAAAAAAATAATAAAAGAATTGTGAATATTTCAAAAAATCTAAATAAATTAATAAATTCCTCTACTTTTGAA
AGTGATATAAATATCATAATTCCTGCCTGTTATGAAAATAATGGTGTTTATTTTTCAATATATACAAAAGGTAAAAGTCC
CCTTATCGCAAAAGAAATAAGGAAAATTGTTGAAAATTATTTAAACGATAACAATATTTTTATGATGCAACAAATAAGGG
ATATTTTAAAGGATAAAGATACACAAAAGACTTCGTCTTTTGAACCAAATCAAAGATTTGATACACAAAAGACTTCGTCT
TTTGAACCATCTCAAACTTTTCCAGAGGAAAAGTTTTACGACTGTAAAAATGGCAAAGCCATTTTGAAGAATCAAAGATT
TGATAATAAAAATAATATAAATTTAAAATCTCAAAAAGATAGAAAAAAAATATTTGAAAAATTATTAAAAAATGAGAATT
TTAAAAAAGAATTTAAGGAATTAATTGATAAATATACTAAATAA

Upstream 100 bases:

>100_bases
AAAGAAGTTCATAAATTATATAATTCTTTTAAATAATATGTGTGTATTTTAATAAATTGGATATAAAATATGTACATACC
ATAATTATAACAGGGATAAA

Downstream 100 bases:

>100_bases
AAAATAATAATAATAATAATAATAATATATGAAAATATGATGAATAGTAAGGAATAAAATAAACTACGGTGTGTATAATG
CTTTTATTTAGGGCGGATTA

Product: siroheme synthase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MMTGNTSFIPLYIKLDNFKVCIFGFGEVGQRRFNKILKGAPKKITIYDKCKHIGVQNTSSFESSQTFPEGKFYDCKNGKA
ILKNQRAGNQRFDTINLNNTKDIKNINFIQQDINNLSNEELENIIKNYDIIITAIDEKNNKRIVNISKNLNKLINSSTFE
SDINIIIPACYENNGVYFSIYTKGKSPLIAKEIRKIVENYLNDNNIFMMQQIRDILKDKDTQKTSSFEPNQRFDTQKTSS
FEPSQTFPEEKFYDCKNGKAILKNQRFDNKNNINLKSQKDRKKIFEKLLKNENFKKEFKELIDKYTK

Sequences:

>Translated_307_residues
MMTGNTSFIPLYIKLDNFKVCIFGFGEVGQRRFNKILKGAPKKITIYDKCKHIGVQNTSSFESSQTFPEGKFYDCKNGKA
ILKNQRAGNQRFDTINLNNTKDIKNINFIQQDINNLSNEELENIIKNYDIIITAIDEKNNKRIVNISKNLNKLINSSTFE
SDINIIIPACYENNGVYFSIYTKGKSPLIAKEIRKIVENYLNDNNIFMMQQIRDILKDKDTQKTSSFEPNQRFDTQKTSS
FEPSQTFPEEKFYDCKNGKAILKNQRFDNKNNINLKSQKDRKKIFEKLLKNENFKKEFKELIDKYTK
>Mature_307_residues
MMTGNTSFIPLYIKLDNFKVCIFGFGEVGQRRFNKILKGAPKKITIYDKCKHIGVQNTSSFESSQTFPEGKFYDCKNGKA
ILKNQRAGNQRFDTINLNNTKDIKNINFIQQDINNLSNEELENIIKNYDIIITAIDEKNNKRIVNISKNLNKLINSSTFE
SDINIIIPACYENNGVYFSIYTKGKSPLIAKEIRKIVENYLNDNNIFMMQQIRDILKDKDTQKTSSFEPNQRFDTQKTSS
FEPSQTFPEEKFYDCKNGKAILKNQRFDNKNNINLKSQKDRKKIFEKLLKNENFKKEFKELIDKYTK

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011128
- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: PF01210 NAD_Gly3P_dh_N [H]

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 35885; Mature: 35885

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTGNTSFIPLYIKLDNFKVCIFGFGEVGQRRFNKILKGAPKKITIYDKCKHIGVQNTSS
CCCCCCCEEEEEEEECCEEEEEEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCC
FESSQTFPEGKFYDCKNGKAILKNQRAGNQRFDTINLNNTKDIKNINFIQQDINNLSNEE
CCCCCCCCCCCEEECCCCCEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHH
LENIIKNYDIIITAIDEKNNKRIVNISKNLNKLINSSTFESDINIIIPACYENNGVYFSI
HHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEE
YTKGKSPLIAKEIRKIVENYLNDNNIFMMQQIRDILKDKDTQKTSSFEPNQRFDTQKTSS
EECCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FEPSQTFPEEKFYDCKNGKAILKNQRFDNKNNINLKSQKDRKKIFEKLLKNENFKKEFKE
CCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LIDKYTK
HHHHHCC
>Mature Secondary Structure
MMTGNTSFIPLYIKLDNFKVCIFGFGEVGQRRFNKILKGAPKKITIYDKCKHIGVQNTSS
CCCCCCCEEEEEEEECCEEEEEEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCC
FESSQTFPEGKFYDCKNGKAILKNQRAGNQRFDTINLNNTKDIKNINFIQQDINNLSNEE
CCCCCCCCCCCEEECCCCCEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHH
LENIIKNYDIIITAIDEKNNKRIVNISKNLNKLINSSTFESDINIIIPACYENNGVYFSI
HHHHHCCCCEEEEEECCCCCCEEEEEHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEE
YTKGKSPLIAKEIRKIVENYLNDNNIFMMQQIRDILKDKDTQKTSSFEPNQRFDTQKTSS
EECCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FEPSQTFPEEKFYDCKNGKAILKNQRFDNKNNINLKSQKDRKKIFEKLLKNENFKKEFKE
CCCCCCCCHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LIDKYTK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]