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The map label for this gene is sucC [H]

Identifier: 150400481

GI number: 150400481

Start: 47244

End: 48326

Strand: Direct

Name: sucC [H]

Synonym: Maeo_0043

Alternate gene names: 150400481

Gene position: 47244-48326 (Clockwise)

Preceding gene: 150400480

Following gene: 150400482

Centisome position: 3.01

GC content: 32.04

Gene sequence:

>1083_bases
ATGAAATTACACGAATACGAAGCAAAGGAAATATTTAAAAAATATAAAATCCCCGTTCCAAATGGGTTTGTTGCATCAAA
ACCAATTAAAGAGCTTAAAACACCATCTGTGATAAAAGCTCAGGTTTTAGTAGGTGGAAGAGGTAAGGCCGGAGGAATAT
TATTTGCAGATACCACAAAAGAGGCCAATCAACATATAAAAAAATTAATTGGTAAAAAAATTAAGGGAGAAAAAGTAAAT
AAAGTATTAATAGAAGAAAAATTACCTATAAAATACGAATATTATCTTGGAATTACAATTGACAGGGCAGAAAAAAAACC
TGTTATAATATTTTCTACCGAAGGGGGCGTAGATATTGAAGAAATAGCAAAAAATACGCCCGAAAAAATAATTAAATATT
ATATAGACCCGCAAAATGAATTTTTACCATATATGGCAAGAAATCTATTAAAAGAAGCAGGACTTCCATCAAACAGAATT
TCAAAAGTTGCAGACATTATATATAAATTATACAATGTATTCAAAGACATGGACGGAACGCTAGTTGAGATAAATCCTTT
GGTAATTACAAAAGATAAAAAAGTGCTTGCAGCAGATGGTGTTTTAAATGTGGATGATGATGCAGAATATAGGCATGATT
ATGCACAATTTGAGTCTTACTCTGAAAAAGATAAATCTGAATTTGCATATGTGGAATTAGATGGAGATATTGCTGTAATT
GGAAATGGTGCAGGTCTAACACTTGCAAGTATGGATATTGTAAAAGAATATGGGGGAGCTCCTGCATGTTTCCTTGATAT
AGGTGGCGGTTCAGATAAAGAAACTGTTGAAAAAGCACTTGAAAAAGCACTTGAAAAAGATATAAAAGGAGTATTTATTA
ATATATTGGGCGGTATTACCCGATGTGATGAAGTGGCAATGGGTATTGTAAAAGCATATTATGAACACCCAGAAATAAAA
TTCTCAGTTAGAATGATGGGCACTAATGAGGAAGAAGGCAGAAAAATATTAACTAAAAACGGAATTCCATTTGAATCTTC
CATGGAGTATGCCGTTGAAAAATTAATCGACATGCTAAAATAA

Upstream 100 bases:

>100_bases
TATGATGATAATATTTTCATTAAGCACAATATGTCCATCGATTTACTTATTATAATATCCAAATGTCATAGTAGTATTAT
TATTTATTTAGGTGATTTGC

Downstream 100 bases:

>100_bases
ATAAAATACATGAAGATATATTGTTTTTGATATACAATATATCAAATCAAATCTCTTCGAGATTTTAGCCATTAATCTTG
TAAAATAGCATAATGCACTA

Product: succinyl-CoA synthetase, beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKLHEYEAKEIFKKYKIPVPNGFVASKPIKELKTPSVIKAQVLVGGRGKAGGILFADTTKEANQHIKKLIGKKIKGEKVN
KVLIEEKLPIKYEYYLGITIDRAEKKPVIIFSTEGGVDIEEIAKNTPEKIIKYYIDPQNEFLPYMARNLLKEAGLPSNRI
SKVADIIYKLYNVFKDMDGTLVEINPLVITKDKKVLAADGVLNVDDDAEYRHDYAQFESYSEKDKSEFAYVELDGDIAVI
GNGAGLTLASMDIVKEYGGAPACFLDIGGGSDKETVEKALEKALEKDIKGVFINILGGITRCDEVAMGIVKAYYEHPEIK
FSVRMMGTNEEEGRKILTKNGIPFESSMEYAVEKLIDMLK

Sequences:

>Translated_360_residues
MKLHEYEAKEIFKKYKIPVPNGFVASKPIKELKTPSVIKAQVLVGGRGKAGGILFADTTKEANQHIKKLIGKKIKGEKVN
KVLIEEKLPIKYEYYLGITIDRAEKKPVIIFSTEGGVDIEEIAKNTPEKIIKYYIDPQNEFLPYMARNLLKEAGLPSNRI
SKVADIIYKLYNVFKDMDGTLVEINPLVITKDKKVLAADGVLNVDDDAEYRHDYAQFESYSEKDKSEFAYVELDGDIAVI
GNGAGLTLASMDIVKEYGGAPACFLDIGGGSDKETVEKALEKALEKDIKGVFINILGGITRCDEVAMGIVKAYYEHPEIK
FSVRMMGTNEEEGRKILTKNGIPFESSMEYAVEKLIDMLK
>Mature_360_residues
MKLHEYEAKEIFKKYKIPVPNGFVASKPIKELKTPSVIKAQVLVGGRGKAGGILFADTTKEANQHIKKLIGKKIKGEKVN
KVLIEEKLPIKYEYYLGITIDRAEKKPVIIFSTEGGVDIEEIAKNTPEKIIKYYIDPQNEFLPYMARNLLKEAGLPSNRI
SKVADIIYKLYNVFKDMDGTLVEINPLVITKDKKVLAADGVLNVDDDAEYRHDYAQFESYSEKDKSEFAYVELDGDIAVI
GNGAGLTLASMDIVKEYGGAPACFLDIGGGSDKETVEKALEKALEKDIKGVFINILGGITRCDEVAMGIVKAYYEHPEIK
FSVRMMGTNEEEGRKILTKNGIPFESSMEYAVEKLIDMLK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=373, Percent_Identity=36.9973190348526, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI157779135, Length=381, Percent_Identity=36.745406824147, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI294862256, Length=360, Percent_Identity=36.6666666666667, Blast_Score=196, Evalue=4e-50,
Organism=Escherichia coli, GI1786948, Length=366, Percent_Identity=38.7978142076503, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17539378, Length=376, Percent_Identity=36.7021276595745, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17567829, Length=376, Percent_Identity=35.1063829787234, Blast_Score=206, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=35.3535353535354, Blast_Score=230, Evalue=3e-61,
Organism=Drosophila melanogaster, GI21356231, Length=384, Percent_Identity=34.375, Blast_Score=207, Evalue=6e-54,
Organism=Drosophila melanogaster, GI161078106, Length=374, Percent_Identity=33.9572192513369, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24645208, Length=374, Percent_Identity=33.9572192513369, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI281361397, Length=375, Percent_Identity=33.8666666666667, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281361395, Length=375, Percent_Identity=33.8666666666667, Blast_Score=185, Evalue=4e-47,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40179; Mature: 40179

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHEYEAKEIFKKYKIPVPNGFVASKPIKELKTPSVIKAQVLVGGRGKAGGILFADTTK
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCEEEECCCH
EANQHIKKLIGKKIKGEKVNKVLIEEKLPIKYEYYLGITIDRAEKKPVIIFSTEGGVDIE
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCHH
EIAKNTPEKIIKYYIDPQNEFLPYMARNLLKEAGLPSNRISKVADIIYKLYNVFKDMDGT
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LVEINPLVITKDKKVLAADGVLNVDDDAEYRHDYAQFESYSEKDKSEFAYVELDGDIAVI
EEEEEEEEEECCCCEEEECCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
GNGAGLTLASMDIVKEYGGAPACFLDIGGGSDKETVEKALEKALEKDIKGVFINILGGIT
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RCDEVAMGIVKAYYEHPEIKFSVRMMGTNEEEGRKILTKNGIPFESSMEYAVEKLIDMLK
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHCCEEEECCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKLHEYEAKEIFKKYKIPVPNGFVASKPIKELKTPSVIKAQVLVGGRGKAGGILFADTTK
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCEEEECCCH
EANQHIKKLIGKKIKGEKVNKVLIEEKLPIKYEYYLGITIDRAEKKPVIIFSTEGGVDIE
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCCCEEEEECCCCCCHH
EIAKNTPEKIIKYYIDPQNEFLPYMARNLLKEAGLPSNRISKVADIIYKLYNVFKDMDGT
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LVEINPLVITKDKKVLAADGVLNVDDDAEYRHDYAQFESYSEKDKSEFAYVELDGDIAVI
EEEEEEEEEECCCCEEEECCEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
GNGAGLTLASMDIVKEYGGAPACFLDIGGGSDKETVEKALEKALEKDIKGVFINILGGIT
ECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RCDEVAMGIVKAYYEHPEIKFSVRMMGTNEEEGRKILTKNGIPFESSMEYAVEKLIDMLK
HHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHCCEEEECCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]