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The map label for this gene is 150400464

Identifier: 150400464

GI number: 150400464

Start: 25552

End: 26850

Strand: Reverse

Name: 150400464

Synonym: Maeo_0025

Alternate gene names: NA

Gene position: 26850-25552 (Counterclockwise)

Preceding gene: 150400470

Following gene: 150400455

Centisome position: 1.71

GC content: 33.1

Gene sequence:

>1299_bases
ATGAAAATATTATTTAGGGGCGGAGCAATGGAAGTAGGTAGAAGTTGTATTGAAGTCAGAAGCGATAACAGCATTATATT
ATTGGATTGTGGAGTAAAACTATTGGAAGAGGATAATAATAAGAATAATAATCCCGAATATCCTGTATTTAATAAATTAT
ATCCTAATGCAGTTTTTATATCTCATGCCCATCTTGACCATACCGGTGCTTTACCTGTGCTTCCCCATATGAAAATCAAT
TGTCCAATATATTCAACCCCTATGACACAGGATTTAACTAAGGAGCTCCTAAAAGATTCATTAAAAATAGGATTAATGGA
GCATGGTCAAGTTCCATTTAATAAAGGAGACCTTAAAAAAGAAATACGACACCATAAAGATATAGAATATAAAAATATGG
AACAATTCAGAGACTTTGAATTTACATATTATGATGCTGGACATATTCCAGGAAGTGCCACAATAGATTTAAATTATGAA
AATGGCAAAAGAATAGTTTATACAGGAGATACAAGAGTTTCAAAAACCAGATTAGTAAATGGGGCAGATTTAAGTTATTG
TGATAATGATATAAATGCCCTAATAATTGAATCTACCTATGGTGGAGAAAATCACCCTGATAGGGAGCTCCTTGAAAAAG
AGTTTCTAAATAAGGTAAAGGAAACAGTGGAAAGAGGGGGAGTTGCTATAATACCAGTTTTTGCAGTAGATAGAAGTCAG
GAAATACTATTGATGCTCAATGAAGTAAATTGGAGCGTTCCAATTTATTTTGATGGATTAGGTATAAAAATAACAAAAAT
TATGTTAAATCAAAATCCGTCATATCTTGAAAATCATGCAAAACTTAAAAGTGCGTTTCTAAGTACGCATAAAGTTAAAG
AAGACCGAAAATATGTAATTGAAGATTTAAGGGAAAATGGCGGAATAATTGTTAGCACGGCTGGAATGCTCAGTGGAGGA
CCAGTATTAAATTATATAGATAACTTTTGGAATGACCCACGGAGCTCCCTGATATTGACAGGTTATCAAGTGAAAAATAC
GGCGGGACGAATTCTCCTCGATACTGGAAAATTCCCAATAGGAGAGTTATTTATAAAACCTAAATTTGAAGTGGCACAGT
ATGAATTTTCGGCACATGCCGACATGGATGAATTAAGAACAATTGTAAAAAAAGCAAATCCTGAAAATCTCATAATACAG
CACGGGGAGGAAGAAAGTATAATGTTATTTAAAGAATGGGCAATTGAAAATGGATTTAATACGATTACTCCGCGATTAGG
GGATAAATTAAAAATATAA

Upstream 100 bases:

>100_bases
ATAAAAATAAATGTATATATAATTAATTAGAATTTACATTAAATTATATGTAATTCTCTCTCTACATTATATATCATATA
AATAAAAGGGGTGATAATAT

Downstream 100 bases:

>100_bases
TTAGAGATACAATCAAATATAAAAAAATATAAAAAAATATAATATAAACAAAATAATATTATTATTCATCAGATTCCAAA
ATAGCATTTTTAATATTGAA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKILFRGGAMEVGRSCIEVRSDNSIILLDCGVKLLEEDNNKNNNPEYPVFNKLYPNAVFISHAHLDHTGALPVLPHMKIN
CPIYSTPMTQDLTKELLKDSLKIGLMEHGQVPFNKGDLKKEIRHHKDIEYKNMEQFRDFEFTYYDAGHIPGSATIDLNYE
NGKRIVYTGDTRVSKTRLVNGADLSYCDNDINALIIESTYGGENHPDRELLEKEFLNKVKETVERGGVAIIPVFAVDRSQ
EILLMLNEVNWSVPIYFDGLGIKITKIMLNQNPSYLENHAKLKSAFLSTHKVKEDRKYVIEDLRENGGIIVSTAGMLSGG
PVLNYIDNFWNDPRSSLILTGYQVKNTAGRILLDTGKFPIGELFIKPKFEVAQYEFSAHADMDELRTIVKKANPENLIIQ
HGEEESIMLFKEWAIENGFNTITPRLGDKLKI

Sequences:

>Translated_432_residues
MKILFRGGAMEVGRSCIEVRSDNSIILLDCGVKLLEEDNNKNNNPEYPVFNKLYPNAVFISHAHLDHTGALPVLPHMKIN
CPIYSTPMTQDLTKELLKDSLKIGLMEHGQVPFNKGDLKKEIRHHKDIEYKNMEQFRDFEFTYYDAGHIPGSATIDLNYE
NGKRIVYTGDTRVSKTRLVNGADLSYCDNDINALIIESTYGGENHPDRELLEKEFLNKVKETVERGGVAIIPVFAVDRSQ
EILLMLNEVNWSVPIYFDGLGIKITKIMLNQNPSYLENHAKLKSAFLSTHKVKEDRKYVIEDLRENGGIIVSTAGMLSGG
PVLNYIDNFWNDPRSSLILTGYQVKNTAGRILLDTGKFPIGELFIKPKFEVAQYEFSAHADMDELRTIVKKANPENLIIQ
HGEEESIMLFKEWAIENGFNTITPRLGDKLKI
>Mature_432_residues
MKILFRGGAMEVGRSCIEVRSDNSIILLDCGVKLLEEDNNKNNNPEYPVFNKLYPNAVFISHAHLDHTGALPVLPHMKIN
CPIYSTPMTQDLTKELLKDSLKIGLMEHGQVPFNKGDLKKEIRHHKDIEYKNMEQFRDFEFTYYDAGHIPGSATIDLNYE
NGKRIVYTGDTRVSKTRLVNGADLSYCDNDINALIIESTYGGENHPDRELLEKEFLNKVKETVERGGVAIIPVFAVDRSQ
EILLMLNEVNWSVPIYFDGLGIKITKIMLNQNPSYLENHAKLKSAFLSTHKVKEDRKYVIEDLRENGGIIVSTAGMLSGG
PVLNYIDNFWNDPRSSLILTGYQVKNTAGRILLDTGKFPIGELFIKPKFEVAQYEFSAHADMDELRTIVKKANPENLIIQ
HGEEESIMLFKEWAIENGFNTITPRLGDKLKI

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=434, Percent_Identity=31.1059907834101, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI7706427, Length=433, Percent_Identity=27.4826789838337, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32564696, Length=437, Percent_Identity=29.7482837528604, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32566029, Length=440, Percent_Identity=27.2727272727273, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323307, Length=461, Percent_Identity=26.0303687635575, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21358523, Length=459, Percent_Identity=29.6296296296296, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24648013, Length=426, Percent_Identity=27.4647887323944, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 49037; Mature: 49037

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILFRGGAMEVGRSCIEVRSDNSIILLDCGVKLLEEDNNKNNNPEYPVFNKLYPNAVFI
CEEEEECCCHHHCHHHHEECCCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
SHAHLDHTGALPVLPHMKINCPIYSTPMTQDLTKELLKDSLKIGLMEHGQVPFNKGDLKK
EEECCCCCCCCCCCCCCEECCCEECCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCHHHH
EIRHHKDIEYKNMEQFRDFEFTYYDAGHIPGSATIDLNYENGKRIVYTGDTRVSKTRLVN
HHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEHEEEEC
GADLSYCDNDINALIIESTYGGENHPDRELLEKEFLNKVKETVERGGVAIIPVFAVDRSQ
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCC
EILLMLNEVNWSVPIYFDGLGIKITKIMLNQNPSYLENHAKLKSAFLSTHKVKEDRKYVI
EEEEEEECCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLRENGGIIVSTAGMLSGGPVLNYIDNFWNDPRSSLILTGYQVKNTAGRILLDTGKFPI
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEECCCCCC
GELFIKPKFEVAQYEFSAHADMDELRTIVKKANPENLIIQHGEEESIMLFKEWAIENGFN
CCEEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHCCCC
TITPRLGDKLKI
CCCCCCCCCCCC
>Mature Secondary Structure
MKILFRGGAMEVGRSCIEVRSDNSIILLDCGVKLLEEDNNKNNNPEYPVFNKLYPNAVFI
CEEEEECCCHHHCHHHHEECCCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCEEEE
SHAHLDHTGALPVLPHMKINCPIYSTPMTQDLTKELLKDSLKIGLMEHGQVPFNKGDLKK
EEECCCCCCCCCCCCCCEECCCEECCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCHHHH
EIRHHKDIEYKNMEQFRDFEFTYYDAGHIPGSATIDLNYENGKRIVYTGDTRVSKTRLVN
HHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEHEEEEC
GADLSYCDNDINALIIESTYGGENHPDRELLEKEFLNKVKETVERGGVAIIPVFAVDRSQ
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCC
EILLMLNEVNWSVPIYFDGLGIKITKIMLNQNPSYLENHAKLKSAFLSTHKVKEDRKYVI
EEEEEEECCCCEEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDLRENGGIIVSTAGMLSGGPVLNYIDNFWNDPRSSLILTGYQVKNTAGRILLDTGKFPI
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEECCCCCC
GELFIKPKFEVAQYEFSAHADMDELRTIVKKANPENLIIQHGEEESIMLFKEWAIENGFN
CCEEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEHHHHCCCC
TITPRLGDKLKI
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]