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The map label for this gene is cbiC [H]

Identifier: 150400454

GI number: 150400454

Start: 17573

End: 18211

Strand: Reverse

Name: cbiC [H]

Synonym: Maeo_0015

Alternate gene names: 150400454

Gene position: 18211-17573 (Counterclockwise)

Preceding gene: 150400455

Following gene: 150400453

Centisome position: 1.16

GC content: 33.33

Gene sequence:

>639_bases
ATGTTTATGGGAGCCTCTACAAAAGACGGAATGGACATAGCCGAAAAGTCAAGATTGATTGTAAAAGAAAAGATAAAAAA
TATATTGGGCGACAAAATAAATAAATATTCAGTAAATGAGATGGGAATAATTGAAAGGGTTGTTCATGCAACAGCAGATG
AAGAATATGCAAAACTTATGGATTTTAGAAATGAACCATTAAAAAATGGAATTGAGGCAATTGCCTCCAATAAACCGATT
GTAGTAGATATTAGCATGGTTGAAGCAGGGATTAGATACAACAATATTCATAATTTTATAAATCATGAAAAAACCCATAA
AATAGCAAAAGAAGAACAAATAACAAGGGCAGTAGCTTCAATGAGAATGGCAAAAGAATATATTGATGGTGGAGTTGTGG
TAATAGGCAATGCTCCAACGGCACTATTTGAAGTTATAAGATTAATTAATGAAGAAGGCATAAAACCAAAGTTAGTTGTG
GGAGCTCCCGTTGGATTTGTAAAGGCAAGTGAATCAAAAGAAGAATTGAGAAATACAAATATACCATCAATAAGCACAGT
AGGGGCAAAGGGAGGAACTCCTGTTGCAGTATCAATTGCCAATGGAATTATTGCACTTAGTAAAAATGAAAGAGTTTAA

Upstream 100 bases:

>100_bases
TGACTATAAATAAAAAAATAAAAATAAAAATAAATAAAGTATTGCGATAAAATAAAACAGTAAAATAATAGTAAAAATAA
AAAATATTTAGGTGAAATTT

Downstream 100 bases:

>100_bases
TTTGTAAAATCCTCGATAAAATAATAAAAAATAAAATTAATAAAAAATAAAATATGACAGCAGTAAATAAAATAATAACA
AATATAGAGGTATAAAATAT

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFMGASTKDGMDIAEKSRLIVKEKIKNILGDKINKYSVNEMGIIERVVHATADEEYAKLMDFRNEPLKNGIEAIASNKPI
VVDISMVEAGIRYNNIHNFINHEKTHKIAKEEQITRAVASMRMAKEYIDGGVVVIGNAPTALFEVIRLINEEGIKPKLVV
GAPVGFVKASESKEELRNTNIPSISTVGAKGGTPVAVSIANGIIALSKNERV

Sequences:

>Translated_212_residues
MFMGASTKDGMDIAEKSRLIVKEKIKNILGDKINKYSVNEMGIIERVVHATADEEYAKLMDFRNEPLKNGIEAIASNKPI
VVDISMVEAGIRYNNIHNFINHEKTHKIAKEEQITRAVASMRMAKEYIDGGVVVIGNAPTALFEVIRLINEEGIKPKLVV
GAPVGFVKASESKEELRNTNIPSISTVGAKGGTPVAVSIANGIIALSKNERV
>Mature_212_residues
MFMGASTKDGMDIAEKSRLIVKEKIKNILGDKINKYSVNEMGIIERVVHATADEEYAKLMDFRNEPLKNGIEAIASNKPI
VVDISMVEAGIRYNNIHNFINHEKTHKIAKEEQITRAVASMRMAKEYIDGGVVVIGNAPTALFEVIRLINEEGIKPKLVV
GAPVGFVKASESKEELRNTNIPSISTVGAKGGTPVAVSIANGIIALSKNERV

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23127; Mature: 23127

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMGASTKDGMDIAEKSRLIVKEKIKNILGDKINKYSVNEMGIIERVVHATADEEYAKLM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
DFRNEPLKNGIEAIASNKPIVVDISMVEAGIRYNNIHNFINHEKTHKIAKEEQITRAVAS
HHCCCHHHHHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRMAKEYIDGGVVVIGNAPTALFEVIRLINEEGIKPKLVVGAPVGFVKASESKEELRNTN
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHCCC
IPSISTVGAKGGTPVAVSIANGIIALSKNERV
CCCEEECCCCCCCCEEEEECCCEEEECCCCCC
>Mature Secondary Structure
MFMGASTKDGMDIAEKSRLIVKEKIKNILGDKINKYSVNEMGIIERVVHATADEEYAKLM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
DFRNEPLKNGIEAIASNKPIVVDISMVEAGIRYNNIHNFINHEKTHKIAKEEQITRAVAS
HHCCCHHHHHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRMAKEYIDGGVVVIGNAPTALFEVIRLINEEGIKPKLVVGAPVGFVKASESKEELRNTN
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHCCC
IPSISTVGAKGGTPVAVSIANGIIALSKNERV
CCCEEECCCCCCCCEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]