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The map label for this gene is pth [H]

Identifier: 150400220

GI number: 150400220

Start: 1504509

End: 1504859

Strand: Reverse

Name: pth [H]

Synonym: Mevan_1481

Alternate gene names: 150400220

Gene position: 1504859-1504509 (Counterclockwise)

Preceding gene: 150400223

Following gene: 150400219

Centisome position: 87.49

GC content: 36.47

Gene sequence:

>351_bases
ATGTATGAACAGGCTATTGTTATAAGAAATGACTTGAAGATGGGAAAGGGAAAAATGGCGGCACAGGCCTGTCATGCATC
TATTCAAGCATATTTACATGCTCAAAAAATAAGCCCGAGTGCAGTTATGTATTGGATGAATGAAGGGCAAAAAAAAGTAG
TGCTAAAAGTAAATTCTGAAAAAGAACTCCTAGAAATATTTAGGGATGTAAATATAGATGGATTACCCTGCAGTTTGATA
AGGGATGCTGGAAAGACCCAGATTGAACCGGGAAGCCTGACTGCTGTTGGAATTGGCCCTGAAAAAGAAGATAAGATTTC
AAAAGTAACGAAAAATCTAAAATTACTTTAA

Upstream 100 bases:

>100_bases
TAATTTGAAGTGACAATAATATTAAAATAGCAATAAGCATTTACTAGTATTACAAATATAAAAAGAGATTCTGATTAAAA
TATTTTTGGATGGCAGAATT

Downstream 100 bases:

>100_bases
AATCCTTAAACTTTAAAATATTTAAAAAACGTAATTATAAGAAAATATAAGAAAAACATAGTTATAAAAATTTTTAGATT
GCCTGTTTTTTAAATATCAA

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MYEQAIVIRNDLKMGKGKMAAQACHASIQAYLHAQKISPSAVMYWMNEGQKKVVLKVNSEKELLEIFRDVNIDGLPCSLI
RDAGKTQIEPGSLTAVGIGPEKEDKISKVTKNLKLL

Sequences:

>Translated_116_residues
MYEQAIVIRNDLKMGKGKMAAQACHASIQAYLHAQKISPSAVMYWMNEGQKKVVLKVNSEKELLEIFRDVNIDGLPCSLI
RDAGKTQIEPGSLTAVGIGPEKEDKISKVTKNLKLL
>Mature_116_residues
MYEQAIVIRNDLKMGKGKMAAQACHASIQAYLHAQKISPSAVMYWMNEGQKKVVLKVNSEKELLEIFRDVNIDGLPCSLI
RDAGKTQIEPGSLTAVGIGPEKEDKISKVTKNLKLL

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis [H]

COG id: COG1990

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH2 family [H]

Homologues:

Organism=Homo sapiens, GI7706351, Length=114, Percent_Identity=50, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558188, Length=117, Percent_Identity=36.7521367521368, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319414, Length=118, Percent_Identity=38.135593220339, Blast_Score=86, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281376919, Length=115, Percent_Identity=44.3478260869565, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644665, Length=115, Percent_Identity=44.3478260869565, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646438, Length=115, Percent_Identity=38.2608695652174, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002833 [H]

Pfam domain/function: PF01981 PTH2 [H]

EC number: =3.1.1.29 [H]

Molecular weight: Translated: 12826; Mature: 12826

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEQAIVIRNDLKMGKGKMAAQACHASIQAYLHAQKISPSAVMYWMNEGQKKVVLKVNSE
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCC
KELLEIFRDVNIDGLPCSLIRDAGKTQIEPGSLTAVGIGPEKEDKISKVTKNLKLL
HHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MYEQAIVIRNDLKMGKGKMAAQACHASIQAYLHAQKISPSAVMYWMNEGQKKVVLKVNSE
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCC
KELLEIFRDVNIDGLPCSLIRDAGKTQIEPGSLTAVGIGPEKEDKISKVTKNLKLL
HHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA