Click here to switch to the map view.

The map label for this gene is pol [H]

Identifier: 150400109

GI number: 150400109

Start: 1394999

End: 1397431

Strand: Reverse

Name: pol [H]

Synonym: Mevan_1367

Alternate gene names: 150400109

Gene position: 1397431-1394999 (Counterclockwise)

Preceding gene: 150400113

Following gene: 150400108

Centisome position: 81.24

GC content: 28.4

Gene sequence:

>2433_bases
ATGGAAAGTTTGGTTGATATTGATTATAATTCAGATGATTTATGTATTTATCTTTATTTTTTGAATCAGACAGTAAAAGA
AAAAAATTTTAAGCCTTATTTTTACTTAAATTCAAGTGATAAGGAAAAAATTTTAAATTATTTAAAAGATTTTGAAGCAA
ATGAACTCGAAAATAATAAAGAAAATAATAAAGAAAATAATAAAGAAAATAATAAGGAAAATAGTAAGAAAAATAGTAAT
TTTAAGACAGTTAATGAACCAAAAGAACCTTTAAAAATGATTGAAAGTATTGATATAGTTGAAAAAATCGTTTTTGATGA
GAAATATAAAAAAAAGAAATTATCAAAAATAACCGTGAAATATCCAACAAACGTAAAAACAATCCGTGAAATACTAATGG
GATTTGAAAAGCTTTATGAATACGATATTCCATTTACAAAAAGATATTTAATTGACAATGAAATTATTCCAACAACAAAC
TGGGATTTTAAAAATAATTTATCAATCAATAACAAAATACCTAATTTAAAAGCTGTTTCTTTCGATATTGAAGTTTATTG
TGAAAAAGAGCCAAGTTCAAAAAAAGACCCGATAATAATGGCTAGTTTCAGTTCAAAAGATGAAAATTTAGTAATATCCA
CAAAAAAATTTAATCACGATAAGTTAGAAGTAGTAAAAGATGAAAAAGAACTTATAAAGAGAATTATAGAAGTTTTAAGT
AGTTATGATGTAATTTACACATATAACGGGGATAATTTTGATTTTCCATACCTTAAAGGGCGTGCTGAAACTTTTGGACT
AGATTTAAAACTTGGAAAAAATGGCGAAAAGATAAAAATTACAAAAGGGGGCATAAATTCAAAAAGTTATATCCCAGGAA
GAGTTCATATCGACTTATACCCGATTGCAAGGCGATTATTAAGTATTGCAAGATATAGACTTGAAAATGTAACTGAAGAA
CTTTTTGGAATTAAAAAAGTAGATGTTGGGCATGAAAATATCCCAAAAATGTGGGATAGTTGTGATGAAACCCTTGTAGA
ATATTCTTTTCAAGATGCGTACTACACTAGAAAGATTGGGGAACAGTTTTTACCTCTTGAAGTAATGTTTTCAAGGGTCG
TAAACCAATCACTTTTTGATATAAACCGTATGAGCAGTAGCCAAATGGTAGAATATCTTCTTTTAAAAAATTCGTATAAA
TTAGGCGTTGTATCCCCAAATAAACCCTCTGGAAATGAATATCAAAAGCGTATAAGGAGTTCATATGAAGGAGGCTATGT
AAAAGAGCCTTTAAAAGGAATACATGAAGATATAATTTCGATGGACTTTTTAAGCCTTTATCCTTCGATAATAATGAGCC
ATAACATAAGCCCTGAAACTATAAATTGCGACTGTTGTAATTTTAAAGAAGCTGAAAAAGTTTTAGGCCATACTTTCTGT
AAAAAACAGACTGGAATAGTTCCAAAAACACTAATGGATTTAATAAATAGGCGAAAAAAGATAAAAGAAATTTTAAAAGA
AAAAGCACTTAAAAACGAATTTGACGAAGAATATAAGATACTTGATTATGAACAAAAATCCATTAAAGTTCTTGCAAATT
CACATTACGGCTACCTAGCATTTCCAATGGCACGCTGGTATTCAAAAGACTGTGCGGAAGTAACAACACATCTTGGACGG
TCATACATACAGAAAACTATTGAAGAAGCGGAAAATTTTGGATTTAATGTAATTTATGCAGATACTGATGGTTTTTATTC
AAAATGGAACTCAAAAAATGGAATAATAAGTAAAGAAAAACTTTTAGAAAAAACTAAAGAATTTTTAAAAACGATAAACG
ATAAACTTCCTGGAGAAATGGAACTTGAATTTGAGGGCCATTTTAAAAGGGGCATATTTGTAACTAAAAAGAAATATGCG
CTTATTGATGAAAATGAAAAGGTAACTATAAAAGGCCTTGAAGTTGTACGGCGTGATTGGTCAAATATTTCTAAAAAAAC
CCAAAAAAATGTACTTGATGAGCTTTTAAAACATGGAAATATTGATTCTGCAAAAAATATAATTCAAAAAACAATTGATG
AATTAAAAAAAGGAAACGTAGATAAAGAAGACCTTTTAATACATACCCAACTTACAAAGCGAATTGAAGATTATAAAACG
ACTGCCCCACACGTTGAAGTTGCAAAAAAAATTGCAAAGGCAGGCAACCGGATAAATGTTGGAGACGTTATAAGCTATAT
TATAACAGATGGGAAAAATTCAATTAGTGAAAGAGCAGAGTTAATAGAAAACGCTAAAAGTTACGATACAAATTATTATA
TTGAAAACCAGATTTTACCCCCCGTAATAAGGATAATGGAAGCTTTGAGTATCTCAAAGGATGAATTAAAAAATTCAAAA
AAACAGACCACTTTGCACTTATTTATGAAATAA

Upstream 100 bases:

>100_bases
ATATAAGCCAATAAACATATAAATTTAACTAATATCTTAATTACTATCCTAATTATTTATCTTATATTCTAAATATAATT
CGTGTAACTTTGGTGTTTTA

Downstream 100 bases:

>100_bases
TTTTAATTATATATTTCATACAAAAATTTATAAAAAGTTATCAAAACTAAATAAAAATCAAAAATAACGAAAAATAAGTA
ACAAAAAGTAATTCAAAACG

Product: DNA polymerase Pol2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 810; Mature: 810

Protein sequence:

>810_residues
MESLVDIDYNSDDLCIYLYFLNQTVKEKNFKPYFYLNSSDKEKILNYLKDFEANELENNKENNKENNKENNKENSKKNSN
FKTVNEPKEPLKMIESIDIVEKIVFDEKYKKKKLSKITVKYPTNVKTIREILMGFEKLYEYDIPFTKRYLIDNEIIPTTN
WDFKNNLSINNKIPNLKAVSFDIEVYCEKEPSSKKDPIIMASFSSKDENLVISTKKFNHDKLEVVKDEKELIKRIIEVLS
SYDVIYTYNGDNFDFPYLKGRAETFGLDLKLGKNGEKIKITKGGINSKSYIPGRVHIDLYPIARRLLSIARYRLENVTEE
LFGIKKVDVGHENIPKMWDSCDETLVEYSFQDAYYTRKIGEQFLPLEVMFSRVVNQSLFDINRMSSSQMVEYLLLKNSYK
LGVVSPNKPSGNEYQKRIRSSYEGGYVKEPLKGIHEDIISMDFLSLYPSIIMSHNISPETINCDCCNFKEAEKVLGHTFC
KKQTGIVPKTLMDLINRRKKIKEILKEKALKNEFDEEYKILDYEQKSIKVLANSHYGYLAFPMARWYSKDCAEVTTHLGR
SYIQKTIEEAENFGFNVIYADTDGFYSKWNSKNGIISKEKLLEKTKEFLKTINDKLPGEMELEFEGHFKRGIFVTKKKYA
LIDENEKVTIKGLEVVRRDWSNISKKTQKNVLDELLKHGNIDSAKNIIQKTIDELKKGNVDKEDLLIHTQLTKRIEDYKT
TAPHVEVAKKIAKAGNRINVGDVISYIITDGKNSISERAELIENAKSYDTNYYIENQILPPVIRIMEALSISKDELKNSK
KQTTLHLFMK

Sequences:

>Translated_810_residues
MESLVDIDYNSDDLCIYLYFLNQTVKEKNFKPYFYLNSSDKEKILNYLKDFEANELENNKENNKENNKENNKENSKKNSN
FKTVNEPKEPLKMIESIDIVEKIVFDEKYKKKKLSKITVKYPTNVKTIREILMGFEKLYEYDIPFTKRYLIDNEIIPTTN
WDFKNNLSINNKIPNLKAVSFDIEVYCEKEPSSKKDPIIMASFSSKDENLVISTKKFNHDKLEVVKDEKELIKRIIEVLS
SYDVIYTYNGDNFDFPYLKGRAETFGLDLKLGKNGEKIKITKGGINSKSYIPGRVHIDLYPIARRLLSIARYRLENVTEE
LFGIKKVDVGHENIPKMWDSCDETLVEYSFQDAYYTRKIGEQFLPLEVMFSRVVNQSLFDINRMSSSQMVEYLLLKNSYK
LGVVSPNKPSGNEYQKRIRSSYEGGYVKEPLKGIHEDIISMDFLSLYPSIIMSHNISPETINCDCCNFKEAEKVLGHTFC
KKQTGIVPKTLMDLINRRKKIKEILKEKALKNEFDEEYKILDYEQKSIKVLANSHYGYLAFPMARWYSKDCAEVTTHLGR
SYIQKTIEEAENFGFNVIYADTDGFYSKWNSKNGIISKEKLLEKTKEFLKTINDKLPGEMELEFEGHFKRGIFVTKKKYA
LIDENEKVTIKGLEVVRRDWSNISKKTQKNVLDELLKHGNIDSAKNIIQKTIDELKKGNVDKEDLLIHTQLTKRIEDYKT
TAPHVEVAKKIAKAGNRINVGDVISYIITDGKNSISERAELIENAKSYDTNYYIENQILPPVIRIMEALSISKDELKNSK
KQTTLHLFMK
>Mature_810_residues
MESLVDIDYNSDDLCIYLYFLNQTVKEKNFKPYFYLNSSDKEKILNYLKDFEANELENNKENNKENNKENNKENSKKNSN
FKTVNEPKEPLKMIESIDIVEKIVFDEKYKKKKLSKITVKYPTNVKTIREILMGFEKLYEYDIPFTKRYLIDNEIIPTTN
WDFKNNLSINNKIPNLKAVSFDIEVYCEKEPSSKKDPIIMASFSSKDENLVISTKKFNHDKLEVVKDEKELIKRIIEVLS
SYDVIYTYNGDNFDFPYLKGRAETFGLDLKLGKNGEKIKITKGGINSKSYIPGRVHIDLYPIARRLLSIARYRLENVTEE
LFGIKKVDVGHENIPKMWDSCDETLVEYSFQDAYYTRKIGEQFLPLEVMFSRVVNQSLFDINRMSSSQMVEYLLLKNSYK
LGVVSPNKPSGNEYQKRIRSSYEGGYVKEPLKGIHEDIISMDFLSLYPSIIMSHNISPETINCDCCNFKEAEKVLGHTFC
KKQTGIVPKTLMDLINRRKKIKEILKEKALKNEFDEEYKILDYEQKSIKVLANSHYGYLAFPMARWYSKDCAEVTTHLGR
SYIQKTIEEAENFGFNVIYADTDGFYSKWNSKNGIISKEKLLEKTKEFLKTINDKLPGEMELEFEGHFKRGIFVTKKKYA
LIDENEKVTIKGLEVVRRDWSNISKKTQKNVLDELLKHGNIDSAKNIIQKTIDELKKGNVDKEDLLIHTQLTKRIEDYKT
TAPHVEVAKKIAKAGNRINVGDVISYIITDGKNSISERAELIENAKSYDTNYYIENQILPPVIRIMEALSISKDELKNSK
KQTTLHLFMK

Specific function: Thought To Be Involved In DNA Repair And/Or Mutagenesis. [C]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=879, Percent_Identity=24.8009101251422, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI106507301, Length=560, Percent_Identity=29.6428571428571, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI153792012, Length=806, Percent_Identity=21.712158808933, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI62198237, Length=348, Percent_Identity=22.4137931034483, Blast_Score=75, Evalue=3e-13,
Organism=Escherichia coli, GI1786246, Length=718, Percent_Identity=23.8161559888579, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17559488, Length=690, Percent_Identity=27.3913043478261, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI32565317, Length=559, Percent_Identity=29.5169946332737, Blast_Score=183, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI86563326, Length=496, Percent_Identity=24.1935483870968, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507143, Length=369, Percent_Identity=25.4742547425474, Blast_Score=77, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320101, Length=684, Percent_Identity=27.046783625731, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324227, Length=445, Percent_Identity=27.4157303370787, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325090, Length=643, Percent_Identity=23.4836702954899, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24664937, Length=880, Percent_Identity=25.3409090909091, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24648780, Length=546, Percent_Identity=28.2051282051282, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586371, Length=560, Percent_Identity=21.7857142857143, Blast_Score=101, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR004578
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 94293; Mature: 94293

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLVDIDYNSDDLCIYLYFLNQTVKEKNFKPYFYLNSSDKEKILNYLKDFEANELENNK
CCCEEECCCCCCCEEEEEEEHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCHHHCCCC
ENNKENNKENNKENSKKNSNFKTVNEPKEPLKMIESIDIVEKIVFDEKYKKKKLSKITVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
YPTNVKTIREILMGFEKLYEYDIPFTKRYLIDNEIIPTTNWDFKNNLSINNKIPNLKAVS
CCCCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCCCCCCCCCCEECCCCCCCEEEE
FDIEVYCEKEPSSKKDPIIMASFSSKDENLVISTKKFNHDKLEVVKDEKELIKRIIEVLS
EEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
SYDVIYTYNGDNFDFPYLKGRAETFGLDLKLGKNGEKIKITKGGINSKSYIPGRVHIDLY
CCCEEEEECCCCCCCCCCCCCCHHEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHH
PIARRLLSIARYRLENVTEELFGIKKVDVGHENIPKMWDSCDETLVEYSFQDAYYTRKIG
HHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFLPLEVMFSRVVNQSLFDINRMSSSQMVEYLLLKNSYKLGVVSPNKPSGNEYQKRIRS
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
SYEGGYVKEPLKGIHEDIISMDFLSLYPSIIMSHNISPETINCDCCNFKEAEKVLGHTFC
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHH
KKQTGIVPKTLMDLINRRKKIKEILKEKALKNEFDEEYKILDYEQKSIKVLANSHYGYLA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHEEEEECCCCCEEE
FPMARWYSKDCAEVTTHLGRSYIQKTIEEAENFGFNVIYADTDGFYSKWNSKNGIISKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCHHH
LLEKTKEFLKTINDKLPGEMELEFEGHFKRGIFVTKKKYALIDENEKVTIKGLEVVRRDW
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECEEEEECCCCEEEEHHHHHHHHHH
SNISKKTQKNVLDELLKHGNIDSAKNIIQKTIDELKKGNVDKEDLLIHTQLTKRIEDYKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHHHHHHHHHCC
TAPHVEVAKKIAKAGNRINVGDVISYIITDGKNSISERAELIENAKSYDTNYYIENQILP
CCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCH
PVIRIMEALSISKDELKNSKKQTTLHLFMK
HHHHHHHHHCCCHHHHHCCHHCEEEEEEEC
>Mature Secondary Structure
MESLVDIDYNSDDLCIYLYFLNQTVKEKNFKPYFYLNSSDKEKILNYLKDFEANELENNK
CCCEEECCCCCCCEEEEEEEHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCHHHCCCC
ENNKENNKENNKENSKKNSNFKTVNEPKEPLKMIESIDIVEKIVFDEKYKKKKLSKITVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE
YPTNVKTIREILMGFEKLYEYDIPFTKRYLIDNEIIPTTNWDFKNNLSINNKIPNLKAVS
CCCCHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCCCCCCCCCCCCEECCCCCCCEEEE
FDIEVYCEKEPSSKKDPIIMASFSSKDENLVISTKKFNHDKLEVVKDEKELIKRIIEVLS
EEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
SYDVIYTYNGDNFDFPYLKGRAETFGLDLKLGKNGEKIKITKGGINSKSYIPGRVHIDLY
CCCEEEEECCCCCCCCCCCCCCHHEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEHH
PIARRLLSIARYRLENVTEELFGIKKVDVGHENIPKMWDSCDETLVEYSFQDAYYTRKIG
HHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFLPLEVMFSRVVNQSLFDINRMSSSQMVEYLLLKNSYKLGVVSPNKPSGNEYQKRIRS
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
SYEGGYVKEPLKGIHEDIISMDFLSLYPSIIMSHNISPETINCDCCNFKEAEKVLGHTFC
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHH
KKQTGIVPKTLMDLINRRKKIKEILKEKALKNEFDEEYKILDYEQKSIKVLANSHYGYLA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHEEEEECCCCCEEE
FPMARWYSKDCAEVTTHLGRSYIQKTIEEAENFGFNVIYADTDGFYSKWNSKNGIISKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCHHH
LLEKTKEFLKTINDKLPGEMELEFEGHFKRGIFVTKKKYALIDENEKVTIKGLEVVRRDW
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECEEEEECCCCEEEEHHHHHHHHHH
SNISKKTQKNVLDELLKHGNIDSAKNIIQKTIDELKKGNVDKEDLLIHTQLTKRIEDYKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHHHHHHHHHCC
TAPHVEVAKKIAKAGNRINVGDVISYIITDGKNSISERAELIENAKSYDTNYYIENQILP
CCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCH
PVIRIMEALSISKDELKNSKKQTTLHLFMK
HHHHHHHHHCCCHHHHHCCHHCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929013 [H]