Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 150399908

GI number: 150399908

Start: 1178814

End: 1180115

Strand: Reverse

Name: paaK [H]

Synonym: Mevan_1165

Alternate gene names: 150399908

Gene position: 1180115-1178814 (Counterclockwise)

Preceding gene: 150399909

Following gene: 150399902

Centisome position: 68.61

GC content: 35.94

Gene sequence:

>1302_bases
TTGATTTGGTCCAGAGAAGAAACTCTAGATAGAGAGGATATCGAAAAAATACAGCTTGAAAGATTAAAAAATGCTGTAAA
ACGGGCCTATAATAACGTGCCCCTTTACAGGAACAAATTTGATAGCGTAAATTTAAAACCTGATGACATAAATTCGCTTG
AAGACCTTAAAAAAGTTCCGTTTACAACTAAGGAAGATTTTAGGGAAAATTATCCGTTTAAAATGTTTGCTGTTCCAAAA
AAAGAAATTATACGAATACACGGATCTTCCGGAACAACTGGAAAACCCACGGTTGTAGGATATACTAAAAAAGACATTGA
AACATGGTCAGAACTCGTTGCACGAGTTATAAGTGCTACGGGAGTAACTAACGAAGATACTGCACAAGTAGCATTTGGAT
ACGGGTTATTTACTGGAGGATTTGGACTTCACTACGGGCTTGAAAAAGTTGGGGTAACGGTAGTTCCAATGTCAAGTGGA
AACACTGAAAAGCAGATAATGCTAATGAAAGATTTTGAAACTACGGTTTTAATATGCACTCCATCATATGCACTTCACAT
TGCAGAAGTTGCTGAAAAAATGGGTATTGACCCTAAAAAAGATTTAAAAATAAAAATCGGTCTTTTTGGAGGGGAAGGTC
TTTCAGAATCTGCCAGAAAAGAACTCGAATCACGATTTTTGATGCTTGCAACATCAAACTACGGAATGAGTGAATTAATG
GGGCCAGGAGTTTCTGGAGAATGCGAATACAAGGTTGGTATGCATATTTCAGAAGATCATTTTATTGCAGAAATTATTGA
CCCTAAAACAGGCGAAGTTTTGCCTGAAGGGGAAGTTGGAGAACTCGTAATTACTGCACTTACAAAAGAGGCACTCCCTG
TTTTAAGATACCGGACTAAAGACCTGACGTCTTTAAATTATAAAAAATGCAAGTGTGGAAGAACTACTGTAAGAATGAAT
AAAATTAAAGGTAGAAGCGACGACATGTTAATTATTAGGGGGGTAAATGTATTCCCTTCACAAATTGAAAGTGTACTTGA
AAGTATTGAAGAAATTGGGCCACATTATGAAATAATTGTTACAAAAAAAGGCCATATGGATGAATTAACAATAAACATTG
AGCTTGCCGATGGAAAGTTTCTTGAAACGTACCGCTGTCTTGAACAGATAAGTAAAAAAGTAGACCATAAGTTAAAAACT
GTTTTAGGATTGAGTTCAAAAATAAATATAGCCCAACCCAGAACCTTAGAACGGTTTGAAGGAAAAGCAAGACGGGTAAA
AGACTTAAGAGATAACGAATAA

Upstream 100 bases:

>100_bases
GCTTTTATAATTAATATTCTAACTTTTGCGGGGAATTATTTTAAACCCGCCATTTTACCATTTAAGTTGGACTGCTAAAA
ACGTAAAGGAGGAGACTAAA

Downstream 100 bases:

>100_bases
TCCAATAAATTAAACTTTTTTAAAACATTTATATTAACTAAATTTTAACTAAATTTGATTATTTTTTAACATCATAATTT
CTTTTTATGTTTTAAATTTT

Product: phenylacetate--CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIWSREETLDREDIEKIQLERLKNAVKRAYNNVPLYRNKFDSVNLKPDDINSLEDLKKVPFTTKEDFRENYPFKMFAVPK
KEIIRIHGSSGTTGKPTVVGYTKKDIETWSELVARVISATGVTNEDTAQVAFGYGLFTGGFGLHYGLEKVGVTVVPMSSG
NTEKQIMLMKDFETTVLICTPSYALHIAEVAEKMGIDPKKDLKIKIGLFGGEGLSESARKELESRFLMLATSNYGMSELM
GPGVSGECEYKVGMHISEDHFIAEIIDPKTGEVLPEGEVGELVITALTKEALPVLRYRTKDLTSLNYKKCKCGRTTVRMN
KIKGRSDDMLIIRGVNVFPSQIESVLESIEEIGPHYEIIVTKKGHMDELTINIELADGKFLETYRCLEQISKKVDHKLKT
VLGLSSKINIAQPRTLERFEGKARRVKDLRDNE

Sequences:

>Translated_433_residues
MIWSREETLDREDIEKIQLERLKNAVKRAYNNVPLYRNKFDSVNLKPDDINSLEDLKKVPFTTKEDFRENYPFKMFAVPK
KEIIRIHGSSGTTGKPTVVGYTKKDIETWSELVARVISATGVTNEDTAQVAFGYGLFTGGFGLHYGLEKVGVTVVPMSSG
NTEKQIMLMKDFETTVLICTPSYALHIAEVAEKMGIDPKKDLKIKIGLFGGEGLSESARKELESRFLMLATSNYGMSELM
GPGVSGECEYKVGMHISEDHFIAEIIDPKTGEVLPEGEVGELVITALTKEALPVLRYRTKDLTSLNYKKCKCGRTTVRMN
KIKGRSDDMLIIRGVNVFPSQIESVLESIEEIGPHYEIIVTKKGHMDELTINIELADGKFLETYRCLEQISKKVDHKLKT
VLGLSSKINIAQPRTLERFEGKARRVKDLRDNE
>Mature_433_residues
MIWSREETLDREDIEKIQLERLKNAVKRAYNNVPLYRNKFDSVNLKPDDINSLEDLKKVPFTTKEDFRENYPFKMFAVPK
KEIIRIHGSSGTTGKPTVVGYTKKDIETWSELVARVISATGVTNEDTAQVAFGYGLFTGGFGLHYGLEKVGVTVVPMSSG
NTEKQIMLMKDFETTVLICTPSYALHIAEVAEKMGIDPKKDLKIKIGLFGGEGLSESARKELESRFLMLATSNYGMSELM
GPGVSGECEYKVGMHISEDHFIAEIIDPKTGEVLPEGEVGELVITALTKEALPVLRYRTKDLTSLNYKKCKCGRTTVRMN
KIKGRSDDMLIIRGVNVFPSQIESVLESIEEIGPHYEIIVTKKGHMDELTINIELADGKFLETYRCLEQISKKVDHKLKT
VLGLSSKINIAQPRTLERFEGKARRVKDLRDNE

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=426, Percent_Identity=48.5915492957746, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48740; Mature: 48740

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWSREETLDREDIEKIQLERLKNAVKRAYNNVPLYRNKFDSVNLKPDDINSLEDLKKVP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
FTTKEDFRENYPFKMFAVPKKEIIRIHGSSGTTGKPTVVGYTKKDIETWSELVARVISAT
CCCHHHHHCCCCEEEEECCHHHEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
GVTNEDTAQVAFGYGLFTGGFGLHYGLEKVGVTVVPMSSGNTEKQIMLMKDFETTVLICT
CCCCCCCCEEEEEEHHHCCCCHHHCCHHHCCEEEEEECCCCCCEEEEEEECCCCEEEEEC
PSYALHIAEVAEKMGIDPKKDLKIKIGLFGGEGLSESARKELESRFLMLATSNYGMSELM
CCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEEEECCCCHHHHC
GPGVSGECEYKVGMHISEDHFIAEIIDPKTGEVLPEGEVGELVITALTKEALPVLRYRTK
CCCCCCCEEEEECCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DLTSLNYKKCKCGRTTVRMNKIKGRSDDMLIIRGVNVFPSQIESVLESIEEIGPHYEIIV
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
TKKGHMDELTINIELADGKFLETYRCLEQISKKVDHKLKTVLGLSSKINIAQPRTLERFE
ECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
GKARRVKDLRDNE
CHHHHHHHCCCCC
>Mature Secondary Structure
MIWSREETLDREDIEKIQLERLKNAVKRAYNNVPLYRNKFDSVNLKPDDINSLEDLKKVP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
FTTKEDFRENYPFKMFAVPKKEIIRIHGSSGTTGKPTVVGYTKKDIETWSELVARVISAT
CCCHHHHHCCCCEEEEECCHHHEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
GVTNEDTAQVAFGYGLFTGGFGLHYGLEKVGVTVVPMSSGNTEKQIMLMKDFETTVLICT
CCCCCCCCEEEEEEHHHCCCCHHHCCHHHCCEEEEEECCCCCCEEEEEEECCCCEEEEEC
PSYALHIAEVAEKMGIDPKKDLKIKIGLFGGEGLSESARKELESRFLMLATSNYGMSELM
CCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEEEECCCCHHHHC
GPGVSGECEYKVGMHISEDHFIAEIIDPKTGEVLPEGEVGELVITALTKEALPVLRYRTK
CCCCCCCEEEEECCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DLTSLNYKKCKCGRTTVRMNKIKGRSDDMLIIRGVNVFPSQIESVLESIEEIGPHYEIIV
CCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
TKKGHMDELTINIELADGKFLETYRCLEQISKKVDHKLKTVLGLSSKINIAQPRTLERFE
ECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
GKARRVKDLRDNE
CHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]