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The map label for this gene is apt1 [H]

Identifier: 150399894

GI number: 150399894

Start: 1164533

End: 1165090

Strand: Reverse

Name: apt1 [H]

Synonym: Mevan_1150

Alternate gene names: 150399894

Gene position: 1165090-1164533 (Counterclockwise)

Preceding gene: 150399895

Following gene: 150399893

Centisome position: 67.74

GC content: 34.23

Gene sequence:

>558_bases
ATGAAAAGGTTACTTGAAAATTCGTTAGAAACATGCCCCATTGTAAAAAGAGGCCCATATCATTATTTTATCCATCCAAT
ATCCGATGGCGTGCCACTAGTTGAGCCCGAACTTTTAAGGGATGTGTCAACAAGGGTAATAAAAATGATTGATACAAATG
TTGATAAAATAGTAACTGCTGAAGCTATGGGAATCCCGATTGTAACTGCTGTATCTATTGCAACAGATATTCCCTATGTA
ATAATGAGAAAAAGAGAATATTTGCTTGAAGGTGAAGTTCCAGTCCATCAAGAAACAGGATACAGTAAAGGAGAACTCTA
TTTAAATGGAATAAATAAAGGAGACAAGGTTGTAATCCTTGATGATGTTATTTCAACAGGAGGAACTCTTGTTGCAATAA
TTCGTGCATTAAAAAGAGCGGGTGCCGACATTAAAGATGTAGTGTGCATTATTGATAGGGGCCAAGGTAAAAATATTGTT
GAAAAAGAAACGGGTTATAAAGTAAAAACTCTTGTAAAAATTGAAGTTGTTGATGGTAAAGTAAAAATTTTAGAATGA

Upstream 100 bases:

>100_bases
ACTCTGTAGAAGTCATGATTTCTGAATTCAAAAATGTATACGATACTCCAAAAAACATATAAACAAAAAAACTAACTTCG
AACTTTAAAACGGTGAAATT

Downstream 100 bases:

>100_bases
TTTGGTGGAACCGTGAAGATAAATCCTACAAAAATCGTTTGTATAGGATTAAATTACATAGACCATGCAAAAGAGCTAAA
TATGGACCTTCCAAAGGAAC

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT 1 [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKRLLENSLETCPIVKRGPYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTNVDKIVTAEAMGIPIVTAVSIATDIPYV
IMRKREYLLEGEVPVHQETGYSKGELYLNGINKGDKVVILDDVISTGGTLVAIIRALKRAGADIKDVVCIIDRGQGKNIV
EKETGYKVKTLVKIEVVDGKVKILE

Sequences:

>Translated_185_residues
MKRLLENSLETCPIVKRGPYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTNVDKIVTAEAMGIPIVTAVSIATDIPYV
IMRKREYLLEGEVPVHQETGYSKGELYLNGINKGDKVVILDDVISTGGTLVAIIRALKRAGADIKDVVCIIDRGQGKNIV
EKETGYKVKTLVKIEVVDGKVKILE
>Mature_185_residues
MKRLLENSLETCPIVKRGPYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTNVDKIVTAEAMGIPIVTAVSIATDIPYV
IMRKREYLLEGEVPVHQETGYSKGELYLNGINKGDKVVILDDVISTGGTLVAIIRALKRAGADIKDVVCIIDRGQGKNIV
EKETGYKVKTLVKIEVVDGKVKILE

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005764
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.7 [H]

Molecular weight: Translated: 20452; Mature: 20452

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLENSLETCPIVKRGPYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTNVDKIVTA
CCCHHHCCHHCCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEH
EAMGIPIVTAVSIATDIPYVIMRKREYLLEGEVPVHQETGYSKGELYLNGINKGDKVVIL
HHCCCCHHHHHHHHHCCCCEEHHHHHHEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
DDVISTGGTLVAIIRALKRAGADIKDVVCIIDRGQGKNIVEKETGYKVKTLVKIEVVDGK
ECHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCE
VKILE
EEEEC
>Mature Secondary Structure
MKRLLENSLETCPIVKRGPYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTNVDKIVTA
CCCHHHCCHHCCCCEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEH
EAMGIPIVTAVSIATDIPYVIMRKREYLLEGEVPVHQETGYSKGELYLNGINKGDKVVIL
HHCCCCHHHHHHHHHCCCCEEHHHHHHEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEE
DDVISTGGTLVAIIRALKRAGADIKDVVCIIDRGQGKNIVEKETGYKVKTLVKIEVVDGK
ECHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCE
VKILE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA