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The map label for this gene is ycgM [C]

Identifier: 150399893

GI number: 150399893

Start: 1163912

End: 1164520

Strand: Reverse

Name: ycgM [C]

Synonym: Mevan_1149

Alternate gene names: 150399893

Gene position: 1164520-1163912 (Counterclockwise)

Preceding gene: 150399894

Following gene: 150399892

Centisome position: 67.7

GC content: 31.53

Gene sequence:

>609_bases
GTGAAGATAAATCCTACAAAAATCGTTTGTATAGGATTAAATTACATAGACCATGCAAAAGAGCTAAATATGGACCTTCC
AAAGGAACCTGTGATATTTTTAAAGCCAGTTTCTTCGATAATATATAATAATGACAGGATAAAAATTCCAGAAATGTCAA
AACAGATAGATTACGAAGCAGAACTTGCAATCGTTATACAAAAAACCTGTAAGTCGGTTAAAAAAGAAGAAGCTAAAAAA
TACATTAAAGGCTACACAATACTAAACGATATTACTGCACGGGATTTGCAGAATAAAGACATTCAGTGGACTCGTGCAAA
ATCTTTTGACACGTTTTGCCCAATTGGGCCTAGAATTGTATCGGATATTAACCCTGAAAATCTTAACATTAAGTTAAAAG
TAAATGGGGAAATAAGACAGCAATCAAACACTGAAAAAATGGTATTTAATGTTTATAAAATAGTAGAATTCGTCTCTTCA
ATAATGACACTTTATCCTGATGATATAATATCTACTGGAACGCCACCTGGAGTTGGACAACTATTTAAAGGGGATACGGT
TGAAATTGAAATTGAAAATATTGGTATTTTACGAAATTTTGTAGAATAA

Upstream 100 bases:

>100_bases
AAATATTGTTGAAAAAGAAACGGGTTATAAAGTAAAAACTCTTGTAAAAATTGAAGTTGTTGATGGTAAAGTAAAAATTT
TAGAATGATTTGGTGGAACC

Downstream 100 bases:

>100_bases
TTTAATATAAATAATTAATTCTAAATAATTAGTTTTAAAGAATTTAATCCAAATTTTAGTCTTATTTTAATTTTATAATT
TAAATTATTTTGTGATAGTA

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: 2-oxohept-3-enedioate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKINPTKIVCIGLNYIDHAKELNMDLPKEPVIFLKPVSSIIYNNDRIKIPEMSKQIDYEAELAIVIQKTCKSVKKEEAKK
YIKGYTILNDITARDLQNKDIQWTRAKSFDTFCPIGPRIVSDINPENLNIKLKVNGEIRQQSNTEKMVFNVYKIVEFVSS
IMTLYPDDIISTGTPPGVGQLFKGDTVEIEIENIGILRNFVE

Sequences:

>Translated_202_residues
MKINPTKIVCIGLNYIDHAKELNMDLPKEPVIFLKPVSSIIYNNDRIKIPEMSKQIDYEAELAIVIQKTCKSVKKEEAKK
YIKGYTILNDITARDLQNKDIQWTRAKSFDTFCPIGPRIVSDINPENLNIKLKVNGEIRQQSNTEKMVFNVYKIVEFVSS
IMTLYPDDIISTGTPPGVGQLFKGDTVEIEIENIGILRNFVE
>Mature_202_residues
MKINPTKIVCIGLNYIDHAKELNMDLPKEPVIFLKPVSSIIYNNDRIKIPEMSKQIDYEAELAIVIQKTCKSVKKEEAKK
YIKGYTILNDITARDLQNKDIQWTRAKSFDTFCPIGPRIVSDINPENLNIKLKVNGEIRQQSNTEKMVFNVYKIVEFVSS
IMTLYPDDIISTGTPPGVGQLFKGDTVEIEIENIGILRNFVE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=45.6730769230769, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI40786394, Length=207, Percent_Identity=45.8937198067633, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI66348062, Length=193, Percent_Identity=39.3782383419689, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=39.3782383419689, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=39.3782383419689, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=35.3846153846154, Blast_Score=142, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=194, Percent_Identity=40.2061855670103, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=36.4035087719298, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28572127, Length=208, Percent_Identity=41.3461538461538, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24663695, Length=211, Percent_Identity=37.914691943128, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571789, Length=207, Percent_Identity=37.6811594202899, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.1.1.68

Molecular weight: Translated: 23053; Mature: 23053

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINPTKIVCIGLNYIDHAKELNMDLPKEPVIFLKPVSSIIYNNDRIKIPEMSKQIDYEA
CCCCCEEEEEEECCHHHHHHHCCCCCCCCCEEEEECHHHHHCCCCCEECCCHHHHCCCCH
ELAIVIQKTCKSVKKEEAKKYIKGYTILNDITARDLQNKDIQWTRAKSFDTFCPIGPRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHH
SDINPENLNIKLKVNGEIRQQSNTEKMVFNVYKIVEFVSSIMTLYPDDIISTGTPPGVGQ
HCCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCH
LFKGDTVEIEIENIGILRNFVE
HCCCCEEEEEECCCHHHHHHCC
>Mature Secondary Structure
MKINPTKIVCIGLNYIDHAKELNMDLPKEPVIFLKPVSSIIYNNDRIKIPEMSKQIDYEA
CCCCCEEEEEEECCHHHHHHHCCCCCCCCCEEEEECHHHHHCCCCCEECCCHHHHCCCCH
ELAIVIQKTCKSVKKEEAKKYIKGYTILNDITARDLQNKDIQWTRAKSFDTFCPIGPRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHH
SDINPENLNIKLKVNGEIRQQSNTEKMVFNVYKIVEFVSSIMTLYPDDIISTGTPPGVGQ
HCCCCCCEEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCH
LFKGDTVEIEIENIGILRNFVE
HCCCCEEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-oxopent-3-ene-1,2,5-tricarboxylate

Specific reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]