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The map label for this gene is 150399846

Identifier: 150399846

GI number: 150399846

Start: 1115716

End: 1116321

Strand: Reverse

Name: 150399846

Synonym: Mevan_1101

Alternate gene names: NA

Gene position: 1116321-1115716 (Counterclockwise)

Preceding gene: 150399847

Following gene: 150399845

Centisome position: 64.9

GC content: 25.58

Gene sequence:

>606_bases
ATGATGCCAGTTTTTTTAGACTTAAAAGGATTTAATGTTTTAATTTTTGGTTTCGGTAATGTTGGAAAGCGTAGATTTGA
AAAATTTCTAAAATCGAACGCTAAATTGACGGTTTACTCTGAAAAAATTGAAAAAGAAGATATTTTAAATTACCCTAAGG
TAAAATTTTTTGAAGAAAATGTAAATAATTTAAGTAATGAAGAACTATATTCAATAATAAAAAATTTTGATATTATAATA
ACTGCAGTAGATAAAAAAAATAACAATAGAATAGTTGAAATTGCTACCTACCTTAAAAAGTATATAAATTCCTCAACATT
TGAAGATAAGGTAAATTTAGTAGTTCCTGCATGCTTTGAAGAAAATGGAGTTTCTTTTGCAATATATACTGGTGGAAAGA
GCCCAATAGTTGCAAGAGAAGTTAGAAAAGTTGTTCAAAACTACTTAAAAAACTCAGAAGATAACATTGAAATACAAGAT
AAGTTGCGGAATTTTTTAAAAGATGAAATTAAAGACCAAGAATTACGTAAAAAAATTCTTGAAAAGGTATTTTCTAATAA
ACAGTTTAAGCTGGAATTTTTAGAACTGATTGAAAAACATAGGTGA

Upstream 100 bases:

>100_bases
TTAGAATTTTCAAAAAAGTTTTCTTGGGACGTTTCTTCAAAAAAAACCTTTGAAGTATATAAAAACCTGCTTGAAAAGTA
ATAGATATAAGTGTGTAATT

Downstream 100 bases:

>100_bases
ATCTATGTTGGTTATTAAAGCAGATTATAAAAAATATCCATTACCGGTTCTTGAAAGCATGCGAATTAATGAAGATGAAT
TTTACGGTAAGTACGATGCT

Product: siroheme synthase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MMPVFLDLKGFNVLIFGFGNVGKRRFEKFLKSNAKLTVYSEKIEKEDILNYPKVKFFEENVNNLSNEELYSIIKNFDIII
TAVDKKNNNRIVEIATYLKKYINSSTFEDKVNLVVPACFEENGVSFAIYTGGKSPIVAREVRKVVQNYLKNSEDNIEIQD
KLRNFLKDEIKDQELRKKILEKVFSNKQFKLEFLELIEKHR

Sequences:

>Translated_201_residues
MMPVFLDLKGFNVLIFGFGNVGKRRFEKFLKSNAKLTVYSEKIEKEDILNYPKVKFFEENVNNLSNEELYSIIKNFDIII
TAVDKKNNNRIVEIATYLKKYINSSTFEDKVNLVVPACFEENGVSFAIYTGGKSPIVAREVRKVVQNYLKNSEDNIEIQD
KLRNFLKDEIKDQELRKKILEKVFSNKQFKLEFLELIEKHR
>Mature_201_residues
MMPVFLDLKGFNVLIFGFGNVGKRRFEKFLKSNAKLTVYSEKIEKEDILNYPKVKFFEENVNNLSNEELYSIIKNFDIII
TAVDKKNNNRIVEIATYLKKYINSSTFEDKVNLVVPACFEENGVSFAIYTGGKSPIVAREVRKVVQNYLKNSEDNIEIQD
KLRNFLKDEIKDQELRKKILEKVFSNKQFKLEFLELIEKHR

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011128
- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: PF01210 NAD_Gly3P_dh_N [H]

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 23620; Mature: 23620

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPVFLDLKGFNVLIFGFGNVGKRRFEKFLKSNAKLTVYSEKIEKEDILNYPKVKFFEEN
CCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCHHHHCCCCCHHHHHHH
VNNLSNEELYSIIKNFDIIITAVDKKNNNRIVEIATYLKKYINSSTFEDKVNLVVPACFE
HCCCCHHHHHHHHCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
ENGVSFAIYTGGKSPIVAREVRKVVQNYLKNSEDNIEIQDKLRNFLKDEIKDQELRKKIL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCHHHHHHHHH
EKVFSNKQFKLEFLELIEKHR
HHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MMPVFLDLKGFNVLIFGFGNVGKRRFEKFLKSNAKLTVYSEKIEKEDILNYPKVKFFEEN
CCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCHHHHCCCCCHHHHHHH
VNNLSNEELYSIIKNFDIIITAVDKKNNNRIVEIATYLKKYINSSTFEDKVNLVVPACFE
HCCCCHHHHHHHHCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
ENGVSFAIYTGGKSPIVAREVRKVVQNYLKNSEDNIEIQDKLRNFLKDEIKDQELRKKIL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCHHHHHHHHH
EKVFSNKQFKLEFLELIEKHR
HHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]