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The map label for this gene is aspC

Identifier: 150399675

GI number: 150399675

Start: 943749

End: 945065

Strand: Reverse

Name: aspC

Synonym: Mevan_0926

Alternate gene names: 150399675

Gene position: 945065-943749 (Counterclockwise)

Preceding gene: 150399676

Following gene: 150399674

Centisome position: 54.94

GC content: 35.0

Gene sequence:

>1317_bases
GTGTATATAATTGCAGACTGGAGGAGAACCCACTATTCAGAACAGGTAATTCCAGAAATGGATGGCCAAGAAGTAATATT
AATGGGGTGGGTTCATTCAATAAGGGCTTTAGGAAAACTTGCATTTATTATTTTAAGAGATAGGGAAGGCTTAATTCAGA
TGGTTGTTCCAAAACAAAAGGTGGACGAAGAAACATTTGAACTAGCTAAAAAATTGGGAAAAGAAGATGTAATTACAATT
CGTGGAAAAGTAGTTGCAAATGAAAAGGCCCCAAAAGGCTTTGAAGTAATTCCGATGGAAATTAGAATATTGAATAAAGC
AGACGCACCTCTTCCATTAGATCCTTCAGAAAAAGTACCTGCAGAAATCGATACAAGACTTGACAGGAGATTTTTAGATA
TTAGGCGACCAAAAATTCAGGCAATATTTAAAATAAGGTCTGAAATGTTGAAATCAATTAGGAAAACGTTTTCAGAAGAA
GGTTTTATTGAAGTAAACACGCCAAAACTTGTTGCAAGTGCTACTGAAGGTGGAACTGAATTATTCCCTATATCATACTT
TGAAAAAGAAGCATTTTTAGGGCAAAGTCCACAACTTTATAAACAGATGATGATGGCAGGTGGATTTGATAAGGTATTTG
AAATTGCACAGATATTTAGGGCAGAAGAGCACAACACGAGAAGACATTTAAACGAGGCTATTTCAATTGATACAGAAATG
TCTTTTGTAAATGAAAAAGATGCAATGGCAATGCTTGAAAAAGTAGTTCACAACTGCTATACAGATATTGAGTATAATAG
GCCTTCTGAAATAGAAACTTTAGAGTTAAATTTTGAAATTCCTGAAAAAACATTCCCTAAGGTAACCTATTCTGAAGCAG
TTGATGTTGCAGTTTCAAAGGGTGTTGAAATAGAATGGGGAGAAGATCTATCAAGGGCTGCTGAAAAAGCAATCGGTGAT
GAAATGGGTGGCCTATACTTTATTACAGAATGGCCAACACAAACAAGGCCATTTTATACACTTCCTGATGAGAATGATAA
TAAAATCTGTAAAGCATTTGATTTAATGTATAAAGAACTTGAAATTTCATCAGGGGCACAAAGAATTCATAAATATGACA
GTTTAGTTCAAAATATTGCCAAAAGAGGTATGAATCCAGATTCCTTTGAAACATACCTTGAAGCATTTAGATATGGGATG
CCCCCACACGCAGGATGGGGACTTGGTGCTGACAGATTTACAATGATTTTAACTAATCAAGAAAATATTCGAGAATGTGT
GCTATTTCCAAGAGATAGACAGAGATTAACTCCATAA

Upstream 100 bases:

>100_bases
AAAAGCATTTTATAATACTATAAATACCATAAAACTATTAGTTTTGATAACCGTTTTACGAATGTAATGGATTAAAGAAT
ACTAGCTATAAGGTGAAAAA

Downstream 100 bases:

>100_bases
TTACCTTATTTTTAATTATTTATTGGCGCCATTTTTTTAAACTGGTAAACTTAATAAAATCTAAACAATGCGGATTTATA
TAAAAAGAAATGTAACTAAT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MYIIADWRRTHYSEQVIPEMDGQEVILMGWVHSIRALGKLAFIILRDREGLIQMVVPKQKVDEETFELAKKLGKEDVITI
RGKVVANEKAPKGFEVIPMEIRILNKADAPLPLDPSEKVPAEIDTRLDRRFLDIRRPKIQAIFKIRSEMLKSIRKTFSEE
GFIEVNTPKLVASATEGGTELFPISYFEKEAFLGQSPQLYKQMMMAGGFDKVFEIAQIFRAEEHNTRRHLNEAISIDTEM
SFVNEKDAMAMLEKVVHNCYTDIEYNRPSEIETLELNFEIPEKTFPKVTYSEAVDVAVSKGVEIEWGEDLSRAAEKAIGD
EMGGLYFITEWPTQTRPFYTLPDENDNKICKAFDLMYKELEISSGAQRIHKYDSLVQNIAKRGMNPDSFETYLEAFRYGM
PPHAGWGLGADRFTMILTNQENIRECVLFPRDRQRLTP

Sequences:

>Translated_438_residues
MYIIADWRRTHYSEQVIPEMDGQEVILMGWVHSIRALGKLAFIILRDREGLIQMVVPKQKVDEETFELAKKLGKEDVITI
RGKVVANEKAPKGFEVIPMEIRILNKADAPLPLDPSEKVPAEIDTRLDRRFLDIRRPKIQAIFKIRSEMLKSIRKTFSEE
GFIEVNTPKLVASATEGGTELFPISYFEKEAFLGQSPQLYKQMMMAGGFDKVFEIAQIFRAEEHNTRRHLNEAISIDTEM
SFVNEKDAMAMLEKVVHNCYTDIEYNRPSEIETLELNFEIPEKTFPKVTYSEAVDVAVSKGVEIEWGEDLSRAAEKAIGD
EMGGLYFITEWPTQTRPFYTLPDENDNKICKAFDLMYKELEISSGAQRIHKYDSLVQNIAKRGMNPDSFETYLEAFRYGM
PPHAGWGLGADRFTMILTNQENIRECVLFPRDRQRLTP
>Mature_438_residues
MYIIADWRRTHYSEQVIPEMDGQEVILMGWVHSIRALGKLAFIILRDREGLIQMVVPKQKVDEETFELAKKLGKEDVITI
RGKVVANEKAPKGFEVIPMEIRILNKADAPLPLDPSEKVPAEIDTRLDRRFLDIRRPKIQAIFKIRSEMLKSIRKTFSEE
GFIEVNTPKLVASATEGGTELFPISYFEKEAFLGQSPQLYKQMMMAGGFDKVFEIAQIFRAEEHNTRRHLNEAISIDTEM
SFVNEKDAMAMLEKVVHNCYTDIEYNRPSEIETLELNFEIPEKTFPKVTYSEAVDVAVSKGVEIEWGEDLSRAAEKAIGD
EMGGLYFITEWPTQTRPFYTLPDENDNKICKAFDLMYKELEISSGAQRIHKYDSLVQNIAKRGMNPDSFETYLEAFRYGM
PPHAGWGLGADRFTMILTNQENIRECVLFPRDRQRLTP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI45439306, Length=438, Percent_Identity=34.0182648401827, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI4758762, Length=429, Percent_Identity=31.9347319347319, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI226491502, Length=444, Percent_Identity=26.5765765765766, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI194272210, Length=451, Percent_Identity=27.2727272727273, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI5031815, Length=453, Percent_Identity=27.1523178807947, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI40789249, Length=447, Percent_Identity=25.0559284116331, Blast_Score=122, Evalue=8e-28,
Organism=Escherichia coli, GI1789256, Length=473, Percent_Identity=28.3298097251586, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787161, Length=449, Percent_Identity=26.0579064587973, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1790571, Length=473, Percent_Identity=27.6955602536998, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788173, Length=294, Percent_Identity=33.6734693877551, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI87082379, Length=318, Percent_Identity=23.8993710691824, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17551876, Length=450, Percent_Identity=32.2222222222222, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71984122, Length=429, Percent_Identity=31.7016317016317, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32566633, Length=296, Percent_Identity=29.3918918918919, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71994340, Length=473, Percent_Identity=24.7357293868922, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17535925, Length=473, Percent_Identity=24.7357293868922, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17535927, Length=473, Percent_Identity=24.7357293868922, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17556372, Length=413, Percent_Identity=26.3922518159806, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323011, Length=451, Percent_Identity=33.4811529933481, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6321807, Length=436, Percent_Identity=30.2752293577982, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6319872, Length=459, Percent_Identity=26.1437908496732, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6325153, Length=267, Percent_Identity=33.7078651685393, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320242, Length=468, Percent_Identity=25.8547008547009, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17136276, Length=455, Percent_Identity=34.5054945054945, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI19921528, Length=426, Percent_Identity=31.924882629108, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19922416, Length=454, Percent_Identity=24.4493392070485, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24640851, Length=458, Percent_Identity=25.5458515283843, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640849, Length=462, Percent_Identity=25.5411255411255, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24584738, Length=318, Percent_Identity=28.9308176100629, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_METVS (A6UQQ8)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323442.1
- ProteinModelPortal:   A6UQQ8
- SMR:   A6UQQ8
- STRING:   A6UQQ8
- GeneID:   5326061
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0926
- eggNOG:   arNOG04316
- HOGENOM:   HBG745843
- OMA:   PAEIDTR
- ProtClustDB:   PRK05159
- GO:   GO:0005737
- HAMAP:   MF_00044_A
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00458

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 50441; Mature: 50441

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIIADWRRTHYSEQVIPEMDGQEVILMGWVHSIRALGKLAFIILRDREGLIQMVVPKQK
CEEEECHHHHCCCHHCCCCCCCCCEEEHHHHHHHHHHHHEEEEEEECCCCCEEEECCHHH
VDEETFELAKKLGKEDVITIRGKVVANEKAPKGFEVIPMEIRILNKADAPLPLDPSEKVP
CCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
AEIDTRLDRRFLDIRRPKIQAIFKIRSEMLKSIRKTFSEEGFIEVNTPKLVASATEGGTE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCE
LFPISYFEKEAFLGQSPQLYKQMMMAGGFDKVFEIAQIFRAEEHNTRRHLNEAISIDTEM
EEEEHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SFVNEKDAMAMLEKVVHNCYTDIEYNRPSEIETLELNFEIPEKTFPKVTYSEAVDVAVSK
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHC
GVEIEWGEDLSRAAEKAIGDEMGGLYFITEWPTQTRPFYTLPDENDNKICKAFDLMYKEL
CCEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHH
EISSGAQRIHKYDSLVQNIAKRGMNPDSFETYLEAFRYGMPPHAGWGLGADRFTMILTNQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
ENIRECVLFPRDRQRLTP
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYIIADWRRTHYSEQVIPEMDGQEVILMGWVHSIRALGKLAFIILRDREGLIQMVVPKQK
CEEEECHHHHCCCHHCCCCCCCCCEEEHHHHHHHHHHHHEEEEEEECCCCCEEEECCHHH
VDEETFELAKKLGKEDVITIRGKVVANEKAPKGFEVIPMEIRILNKADAPLPLDPSEKVP
CCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
AEIDTRLDRRFLDIRRPKIQAIFKIRSEMLKSIRKTFSEEGFIEVNTPKLVASATEGGTE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCE
LFPISYFEKEAFLGQSPQLYKQMMMAGGFDKVFEIAQIFRAEEHNTRRHLNEAISIDTEM
EEEEHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SFVNEKDAMAMLEKVVHNCYTDIEYNRPSEIETLELNFEIPEKTFPKVTYSEAVDVAVSK
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHC
GVEIEWGEDLSRAAEKAIGDEMGGLYFITEWPTQTRPFYTLPDENDNKICKAFDLMYKEL
CCEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHH
EISSGAQRIHKYDSLVQNIAKRGMNPDSFETYLEAFRYGMPPHAGWGLGADRFTMILTNQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
ENIRECVLFPRDRQRLTP
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA