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The map label for this gene is ribD [C]

Identifier: 150399410

GI number: 150399410

Start: 708376

End: 709449

Strand: Reverse

Name: ribD [C]

Synonym: Mevan_0659

Alternate gene names: 150399410

Gene position: 709449-708376 (Counterclockwise)

Preceding gene: 150399411

Following gene: 150399409

Centisome position: 41.25

GC content: 30.91

Gene sequence:

>1074_bases
ATGGATAAAAAGGAATCTTTAAGGAAAATTGTTGAAACTATTGATAATATAAAAGAATTGGCAGAATATGGCATTCCAGT
ACTGATTGAAGGAAAAAAGGATGCTGAATCATTGAAAAATTTGGGAATTTCTGGAAGATTTATCTTTGTTTCAAGAACTC
CAATATTTCAAATTGCAGACACTTTAAAAAAAGAAGGTATTTTAGAAGTAATTTTACTAACTGACTTTGATAAAGCAGGT
AAAAAGTATGCAAGGGAAATACTTTCGGAATTTCAAAATAGGGGCATTAAAGTAAATAATATTTTAAGAAACGAACTACT
TAAATACTCCAGAGGAGATTTAAAAGATATAGAGAGTATTTATGCATATATTTCAAGAAGGGTCGATATTATGCCAAATT
TTGACGATATGTTGTTACCGCATGTTATATCTAATGTAGGAATGACTCTTGATGGAAAACTTGCAACAGTTTCAAACGAC
TCAAGAATTTCATCTGAAAATGATTTAAAAAGAGTACATGAACTAAGAAAAGAAGTTGATGGAATACTGGTCGGTATTGG
AACTATATTGAAAGACGATCCAAGGTTAACGGTACATAAGGTACCTGCAGTGCCTAAGGAAAACCCGATAAGAATTGTGG
TTGATAGCAGTTTAAGAATTCCAATGACTGCAAGGGTATTAAATAGTGATGCAAAAACCATCATTGCAACTACAAAACCT
TCTTCAAATGAAAAAGATGAAAAAATTCGAAAATTAATCAGTATGGGAGTTACAGTTATTCAAACAGGTGCCAAAAAAGT
TAATTTAAAAGATTTAATGAATGAATTATATAAACAAGGCATAAAAAAGATACTGCTTGAAGGAGGGGGAACTTTAAACT
TTGGAATGTTTAAAGAAAACTTGATAAGTGAAATAAGGGTATATGTAGCTCCAAAAATATTTGGTGGGTCAAATGCGCCG
ACCTATGTTGATGGTGAAGGATTTAAAACAGTTGAAGATAGTCCAAAACTTGAATTAAAGAACCATTACATTCTTGATGA
TGGAATAATCCTTGAATATATCGTGATTAAATAA

Upstream 100 bases:

>100_bases
AATGCCACTTTAGTATTTACTTTTACTATTTCTTTAAGAATAATCTTTAGTAATTACTTTAAATTTATTTAAAATTTATT
TTAGTTAATAACGTGGTAAC

Downstream 100 bases:

>100_bases
AAAATCTTGCTAAATACTATTTTTATATTATTCTTATATTATTTTTTAAAGTTATATATTATGTATCTAAATACATAAAT
TTAAATAAATTATCCAGATA

Product: bifunctional RNAse/5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDKKESLRKIVETIDNIKELAEYGIPVLIEGKKDAESLKNLGISGRFIFVSRTPIFQIADTLKKEGILEVILLTDFDKAG
KKYAREILSEFQNRGIKVNNILRNELLKYSRGDLKDIESIYAYISRRVDIMPNFDDMLLPHVISNVGMTLDGKLATVSND
SRISSENDLKRVHELRKEVDGILVGIGTILKDDPRLTVHKVPAVPKENPIRIVVDSSLRIPMTARVLNSDAKTIIATTKP
SSNEKDEKIRKLISMGVTVIQTGAKKVNLKDLMNELYKQGIKKILLEGGGTLNFGMFKENLISEIRVYVAPKIFGGSNAP
TYVDGEGFKTVEDSPKLELKNHYILDDGIILEYIVIK

Sequences:

>Translated_357_residues
MDKKESLRKIVETIDNIKELAEYGIPVLIEGKKDAESLKNLGISGRFIFVSRTPIFQIADTLKKEGILEVILLTDFDKAG
KKYAREILSEFQNRGIKVNNILRNELLKYSRGDLKDIESIYAYISRRVDIMPNFDDMLLPHVISNVGMTLDGKLATVSND
SRISSENDLKRVHELRKEVDGILVGIGTILKDDPRLTVHKVPAVPKENPIRIVVDSSLRIPMTARVLNSDAKTIIATTKP
SSNEKDEKIRKLISMGVTVIQTGAKKVNLKDLMNELYKQGIKKILLEGGGTLNFGMFKENLISEIRVYVAPKIFGGSNAP
TYVDGEGFKTVEDSPKLELKNHYILDDGIILEYIVIK
>Mature_357_residues
MDKKESLRKIVETIDNIKELAEYGIPVLIEGKKDAESLKNLGISGRFIFVSRTPIFQIADTLKKEGILEVILLTDFDKAG
KKYAREILSEFQNRGIKVNNILRNELLKYSRGDLKDIESIYAYISRRVDIMPNFDDMLLPHVISNVGMTLDGKLATVSND
SRISSENDLKRVHELRKEVDGILVGIGTILKDDPRLTVHKVPAVPKENPIRIVVDSSLRIPMTARVLNSDAKTIIATTKP
SSNEKDEKIRKLISMGVTVIQTGAKKVNLKDLMNELYKQGIKKILLEGGGTLNFGMFKENLISEIRVYVAPKIFGGSNAP
TYVDGEGFKTVEDSPKLELKNHYILDDGIILEYIVIK

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=301, Percent_Identity=29.2358803986711, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 40039; Mature: 40039

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKESLRKIVETIDNIKELAEYGIPVLIEGKKDAESLKNLGISGRFIFVSRTPIFQIAD
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCHHHHHH
TLKKEGILEVILLTDFDKAGKKYAREILSEFQNRGIKVNNILRNELLKYSRGDLKDIESI
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCHHHHHHH
YAYISRRVDIMPNFDDMLLPHVISNVGMTLDGKLATVSNDSRISSENDLKRVHELRKEVD
HHHHHHCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHHH
GILVGIGTILKDDPRLTVHKVPAVPKENPIRIVVDSSLRIPMTARVLNSDAKTIIATTKP
HEEEEHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEECCC
SSNEKDEKIRKLISMGVTVIQTGAKKVNLKDLMNELYKQGIKKILLEGGGTLNFGMFKEN
CCCCHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
LISEIRVYVAPKIFGGSNAPTYVDGEGFKTVEDSPKLELKNHYILDDGIILEYIVIK
HHHHHHHHCCCEEECCCCCCCEECCCCCCCCCCCCCEEECCCEEECCCEEEEEEEEC
>Mature Secondary Structure
MDKKESLRKIVETIDNIKELAEYGIPVLIEGKKDAESLKNLGISGRFIFVSRTPIFQIAD
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCEEEEEECCCHHHHHH
TLKKEGILEVILLTDFDKAGKKYAREILSEFQNRGIKVNNILRNELLKYSRGDLKDIESI
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHCCCCHHHHHHH
YAYISRRVDIMPNFDDMLLPHVISNVGMTLDGKLATVSNDSRISSENDLKRVHELRKEVD
HHHHHHCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHHH
GILVGIGTILKDDPRLTVHKVPAVPKENPIRIVVDSSLRIPMTARVLNSDAKTIIATTKP
HEEEEHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEECCC
SSNEKDEKIRKLISMGVTVIQTGAKKVNLKDLMNELYKQGIKKILLEGGGTLNFGMFKEN
CCCCHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
LISEIRVYVAPKIFGGSNAPTYVDGEGFKTVEDSPKLELKNHYILDDGIILEYIVIK
HHHHHHHHCCCEEECCCCCCCEECCCCCCCCCCCCCEEECCCEEECCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]