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The map label for this gene is argD [H]

Identifier: 150399179

GI number: 150399179

Start: 480555

End: 481745

Strand: Reverse

Name: argD [H]

Synonym: Mevan_0426

Alternate gene names: 150399179

Gene position: 481745-480555 (Counterclockwise)

Preceding gene: 150399185

Following gene: 150399178

Centisome position: 28.01

GC content: 33.84

Gene sequence:

>1191_bases
ATGCTTAGTAATCAAGAAATGGATAATGTAATCCTTGAAGAAAGTAAATATGTCATAAATACGTATGGAAGAGTTCCAGC
AGTTCTCGTAAAAGGGGATGGAATGAATGTATATGATATTAATGGAAATAGTTATGTTGATTTTCTTTCAGGAATATCTG
TAAACAATGTTGGACACTGTCACCCTAAAATTGTTGAAACAATTAAAAAGCAGGCTGAAACACTTATTCACGTTTCAAAT
ATATACTATAATATTCCCCAAGTAAATCTTGCAAAAAAACTCGTGAATATAAGTGGGCTTGATAAAGCATTCTTTTGTAA
CAGCGGTGCGGAGGCAAACGAAGCTGCAATAAAACTTTCAAGAAAGTATTCAAAAGCTTTTGGAAAAGAAGGGGAAATTA
TTACAATGGAGCATGCATTCCACGGTAGAACCCTAACAACGATTACTGCAACCCCTAAACCAAAGTATCAGGAAGGTTAC
GATCCATTACCGACAGGATTTAAGCATGTTCCTTTTAATGATATAGAAAAATTAAAAGAGTCCATTTCAAATAAAACCGC
AGCAATAATGATAGAGCCAGTTCAGGGCGAAGGTGGAATTCATATTGCAGACCAAGAATATTTAAAAGCTGTTCGTGAGT
TATGTGATGATAAAAATATTGTTTTGATATTTGATGAGGTACAGTGCGGGCTTGGAAGAACTGGTAAAATGTTTGCATTT
GAACATTACGGTGTAAAACCCGATATAATAACATTAGCAAAGGCACTTGGTAGCGGAATCCCAATTGGTGCAATGATTGC
AAAAGACGAAGTTTCAAATGCGTTTACTCCTGGAAGCCATGGTACTACTTTTGGAGGAAATCCTCTTGCATGCGCTACTG
CAATTACTTCAATTAATTTAATTTCAGAACTTTTAAATAATACGAACGAAATGGGCGTTTATTTTACTGATAAATTGAAG
AAAATTGAAGAAAAATATGACTTTGTAAGGGAAGTTAGATCAATTGGACTTATGACGGGACTTGAATTGAGTTTCAATGG
TTCAAACATCGTTCAGGAAATGTTTAAACAAGGTTACCTTATAAACTGTACTTCAGATACGGTTTTAAGATTTTTACCTC
CATTAATTATTCAAAAAGAGCATATTGATGGAATGGTATCAAGTCTTGATGATGTATTTTCAAAAATATAA

Upstream 100 bases:

>100_bases
ATTGTATTAATTAATTTCTAAAAATATGTTTTTATTAGTAAGTGAAGTAAAAATGTCTAATTATTTTAAAATGTACTAAT
TTAATTTTTATGGTGATATT

Downstream 100 bases:

>100_bases
ATATAAATATAAATATAAATATAAATATAAATTTATTTTAAATTAAAATACAATTTATTTTAATAACATTGTATTAACAT
TAAGATATCACTTATACCAT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLSNQEMDNVILEESKYVINTYGRVPAVLVKGDGMNVYDINGNSYVDFLSGISVNNVGHCHPKIVETIKKQAETLIHVSN
IYYNIPQVNLAKKLVNISGLDKAFFCNSGAEANEAAIKLSRKYSKAFGKEGEIITMEHAFHGRTLTTITATPKPKYQEGY
DPLPTGFKHVPFNDIEKLKESISNKTAAIMIEPVQGEGGIHIADQEYLKAVRELCDDKNIVLIFDEVQCGLGRTGKMFAF
EHYGVKPDIITLAKALGSGIPIGAMIAKDEVSNAFTPGSHGTTFGGNPLACATAITSINLISELLNNTNEMGVYFTDKLK
KIEEKYDFVREVRSIGLMTGLELSFNGSNIVQEMFKQGYLINCTSDTVLRFLPPLIIQKEHIDGMVSSLDDVFSKI

Sequences:

>Translated_396_residues
MLSNQEMDNVILEESKYVINTYGRVPAVLVKGDGMNVYDINGNSYVDFLSGISVNNVGHCHPKIVETIKKQAETLIHVSN
IYYNIPQVNLAKKLVNISGLDKAFFCNSGAEANEAAIKLSRKYSKAFGKEGEIITMEHAFHGRTLTTITATPKPKYQEGY
DPLPTGFKHVPFNDIEKLKESISNKTAAIMIEPVQGEGGIHIADQEYLKAVRELCDDKNIVLIFDEVQCGLGRTGKMFAF
EHYGVKPDIITLAKALGSGIPIGAMIAKDEVSNAFTPGSHGTTFGGNPLACATAITSINLISELLNNTNEMGVYFTDKLK
KIEEKYDFVREVRSIGLMTGLELSFNGSNIVQEMFKQGYLINCTSDTVLRFLPPLIIQKEHIDGMVSSLDDVFSKI
>Mature_396_residues
MLSNQEMDNVILEESKYVINTYGRVPAVLVKGDGMNVYDINGNSYVDFLSGISVNNVGHCHPKIVETIKKQAETLIHVSN
IYYNIPQVNLAKKLVNISGLDKAFFCNSGAEANEAAIKLSRKYSKAFGKEGEIITMEHAFHGRTLTTITATPKPKYQEGY
DPLPTGFKHVPFNDIEKLKESISNKTAAIMIEPVQGEGGIHIADQEYLKAVRELCDDKNIVLIFDEVQCGLGRTGKMFAF
EHYGVKPDIITLAKALGSGIPIGAMIAKDEVSNAFTPGSHGTTFGGNPLACATAITSINLISELLNNTNEMGVYFTDKLK
KIEEKYDFVREVRSIGLMTGLELSFNGSNIVQEMFKQGYLINCTSDTVLRFLPPLIIQKEHIDGMVSSLDDVFSKI

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=34.625322997416, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI284507298, Length=288, Percent_Identity=35.0694444444444, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI13994255, Length=370, Percent_Identity=32.7027027027027, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=29.7820823244552, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=30.3664921465969, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI226442705, Length=413, Percent_Identity=29.2978208232446, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=27.0531400966184, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI188536080, Length=424, Percent_Identity=24.2924528301887, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679950, Length=424, Percent_Identity=24.2924528301887, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679946, Length=424, Percent_Identity=24.2924528301887, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=41.7525773195876, Blast_Score=341, Evalue=4e-95,
Organism=Escherichia coli, GI1788044, Length=375, Percent_Identity=42.1333333333333, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI145693181, Length=403, Percent_Identity=37.7171215880893, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=36.6412213740458, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=31.6279069767442, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786991, Length=393, Percent_Identity=27.9898218829517, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786349, Length=338, Percent_Identity=27.2189349112426, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=381, Percent_Identity=36.745406824147, Blast_Score=267, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=32.6190476190476, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=38.0769230769231, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=428, Percent_Identity=29.4392523364486, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71981843, Length=168, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=422, Percent_Identity=24.8815165876777, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71992985, Length=122, Percent_Identity=35.2459016393443, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=406, Percent_Identity=35.9605911330049, Blast_Score=256, Evalue=5e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=34.390243902439, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6324386, Length=312, Percent_Identity=28.2051282051282, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=422, Percent_Identity=23.4597156398104, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=36.340206185567, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=29.9065420560748, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI28574759, Length=412, Percent_Identity=30.5825242718447, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=28.5035629453682, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43604; Mature: 43604

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNQEMDNVILEESKYVINTYGRVPAVLVKGDGMNVYDINGNSYVDFLSGISVNNVGHC
CCCCCCHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEECCCCCHHHHHCCCCCCCCCCC
HPKIVETIKKQAETLIHVSNIYYNIPQVNLAKKLVNISGLDKAFFCNSGAEANEAAIKLS
CHHHHHHHHHHHHHHEEEHHHEEECCCHHHHHHHHHHCCCCHHEEECCCCCCCHHHHHHH
RKYSKAFGKEGEIITMEHAFHGRTLTTITATPKPKYQEGYDPLPTGFKHVPFNDIEKLKE
HHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SISNKTAAIMIEPVQGEGGIHIADQEYLKAVRELCDDKNIVLIFDEVQCGLGRTGKMFAF
HHCCCEEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEE
EHYGVKPDIITLAKALGSGIPIGAMIAKDEVSNAFTPGSHGTTFGGNPLACATAITSINL
ECCCCCCHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ISELLNNTNEMGVYFTDKLKKIEEKYDFVREVRSIGLMTGLELSFNGSNIVQEMFKQGYL
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEE
INCTSDTVLRFLPPLIIQKEHIDGMVSSLDDVFSKI
EEECHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSNQEMDNVILEESKYVINTYGRVPAVLVKGDGMNVYDINGNSYVDFLSGISVNNVGHC
CCCCCCHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEECCCCCHHHHHCCCCCCCCCCC
HPKIVETIKKQAETLIHVSNIYYNIPQVNLAKKLVNISGLDKAFFCNSGAEANEAAIKLS
CHHHHHHHHHHHHHHEEEHHHEEECCCHHHHHHHHHHCCCCHHEEECCCCCCCHHHHHHH
RKYSKAFGKEGEIITMEHAFHGRTLTTITATPKPKYQEGYDPLPTGFKHVPFNDIEKLKE
HHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SISNKTAAIMIEPVQGEGGIHIADQEYLKAVRELCDDKNIVLIFDEVQCGLGRTGKMFAF
HHCCCEEEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEE
EHYGVKPDIITLAKALGSGIPIGAMIAKDEVSNAFTPGSHGTTFGGNPLACATAITSINL
ECCCCCCHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ISELLNNTNEMGVYFTDKLKKIEEKYDFVREVRSIGLMTGLELSFNGSNIVQEMFKQGYL
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCEE
INCTSDTVLRFLPPLIIQKEHIDGMVSSLDDVFSKI
EEECHHHHHHHCCHHHEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]