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The map label for this gene is galE [C]

Identifier: 150399168

GI number: 150399168

Start: 469038

End: 469916

Strand: Reverse

Name: galE [C]

Synonym: Mevan_0415

Alternate gene names: 150399168

Gene position: 469916-469038 (Counterclockwise)

Preceding gene: 150399169

Following gene: 150399167

Centisome position: 27.32

GC content: 29.01

Gene sequence:

>879_bases
TTGAAAATTTTAGTAACTGGCGGTGCAGGGTTTATTGGAAGCCATATTGTTGATTTATTAATTGAAAATGGGCATGATGT
AACAATTTTAGATAATTTAAGTACTGGAAATGAAAAAAACATAAATAACTCCGCAAAATTTATAAACGGAGACATATTGG
ATAAAAATTTAGATTTAACAGGATTTGAATGCGTAATTCATGAAGCAGCACAGATTAATGTTAGAACATCTGTTGAAGAC
CCTATTTTAGATGCAAATATAAATATCCTTGGAACAATCAATATTTTAGAAAAAATGAAAGAATATGGTGTAAAAAAGAT
TATTTTTTCATCTTCCGGCGGTGCAGTGTATGGGGAACCAAAATATTTACCGGTTGATGAAAAACACGATGTAAATCCAC
TTTCACCATATGGATTAAGTAAATTTTGTGCAGAAGAATATATCAAATTATATAATAGACTTTACAATATCGAATACTGT
ATTTTAAGGTATTCTAATGTTTATGGGAAACGTCAAGACCCCCTTGGTGAAGCAGGCGTTATTTCAATCTTTATTGATAA
AATGAAAAAAGGAGAAAGTCCAATAATTTATGGAAATGGAAACCAGACACGGGATTTTGTAAATGTTAAAGATGTTTCAA
AAGCAAATTTAATGGCATTAAATTGGAAAAATGAGATTGTAAATATTGGTTCTGGAAAAGAAACATCTGTAAATGAACTT
TTTAAGATTATATCTTCTGAAGTCGGCTTTGATAAAAATCCAATTTATGAAAAAGAGCGAGATGGCGAAGTTTATAGAAT
TTATATTGATTATAATTATGCTAAAAGTTTAGGATGGATTCCAGAAGTTGAAATGGATAATGGAATTAAAGATATTTAA

Upstream 100 bases:

>100_bases
TAGTTGTATAGTTAATTATGTAAAATTTAATGAATAATTTAAATTTACTTTTTTAAATTAATTGGTAAATTAAATTAATT
GGTAAAATCAAGGTGAAACT

Downstream 100 bases:

>100_bases
TTAAATTTTTTATTTTTAAGGGGATAATTTTTGAGTTATAAAGATAGAATGATTAAGGGTGCTGCATGGAATTTTTTATT
CTTAATGTTAGCAGCCCCTA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKILVTGGAGFIGSHIVDLLIENGHDVTILDNLSTGNEKNINNSAKFINGDILDKNLDLTGFECVIHEAAQINVRTSVED
PILDANINILGTINILEKMKEYGVKKIIFSSSGGAVYGEPKYLPVDEKHDVNPLSPYGLSKFCAEEYIKLYNRLYNIEYC
ILRYSNVYGKRQDPLGEAGVISIFIDKMKKGESPIIYGNGNQTRDFVNVKDVSKANLMALNWKNEIVNIGSGKETSVNEL
FKIISSEVGFDKNPIYEKERDGEVYRIYIDYNYAKSLGWIPEVEMDNGIKDI

Sequences:

>Translated_292_residues
MKILVTGGAGFIGSHIVDLLIENGHDVTILDNLSTGNEKNINNSAKFINGDILDKNLDLTGFECVIHEAAQINVRTSVED
PILDANINILGTINILEKMKEYGVKKIIFSSSGGAVYGEPKYLPVDEKHDVNPLSPYGLSKFCAEEYIKLYNRLYNIEYC
ILRYSNVYGKRQDPLGEAGVISIFIDKMKKGESPIIYGNGNQTRDFVNVKDVSKANLMALNWKNEIVNIGSGKETSVNEL
FKIISSEVGFDKNPIYEKERDGEVYRIYIDYNYAKSLGWIPEVEMDNGIKDI
>Mature_292_residues
MKILVTGGAGFIGSHIVDLLIENGHDVTILDNLSTGNEKNINNSAKFINGDILDKNLDLTGFECVIHEAAQINVRTSVED
PILDANINILGTINILEKMKEYGVKKIIFSSSGGAVYGEPKYLPVDEKHDVNPLSPYGLSKFCAEEYIKLYNRLYNIEYC
ILRYSNVYGKRQDPLGEAGVISIFIDKMKKGESPIIYGNGNQTRDFVNVKDVSKANLMALNWKNEIVNIGSGKETSVNEL
FKIISSEVGFDKNPIYEKERDGEVYRIYIDYNYAKSLGWIPEVEMDNGIKDI

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=331, Percent_Identity=32.02416918429, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56118217, Length=331, Percent_Identity=32.02416918429, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI189083684, Length=331, Percent_Identity=32.02416918429, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI42516563, Length=300, Percent_Identity=30.6666666666667, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI7657641, Length=311, Percent_Identity=34.7266881028939, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI193211614, Length=224, Percent_Identity=27.2321428571429, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI8393516, Length=224, Percent_Identity=27.2321428571429, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786974, Length=325, Percent_Identity=30.1538461538462, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788353, Length=331, Percent_Identity=29.607250755287, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI48994969, Length=326, Percent_Identity=30.3680981595092, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790049, Length=259, Percent_Identity=30.1158301158301, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788365, Length=313, Percent_Identity=21.0862619808307, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788366, Length=266, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=299, Percent_Identity=31.438127090301, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982035, Length=337, Percent_Identity=29.3768545994065, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71982038, Length=339, Percent_Identity=29.2035398230088, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI115532424, Length=318, Percent_Identity=28.9308176100629, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568069, Length=317, Percent_Identity=30.5993690851735, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539422, Length=334, Percent_Identity=23.3532934131737, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133901786, Length=334, Percent_Identity=23.3532934131737, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133901788, Length=334, Percent_Identity=23.3532934131737, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133901790, Length=334, Percent_Identity=23.3532934131737, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17539424, Length=334, Percent_Identity=23.3532934131737, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507723, Length=336, Percent_Identity=22.9166666666667, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=31.044776119403, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356223, Length=302, Percent_Identity=31.7880794701987, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19923002, Length=331, Percent_Identity=31.7220543806647, Blast_Score=117, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 32708; Mature: 32708

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTGGAGFIGSHIVDLLIENGHDVTILDNLSTGNEKNINNSAKFINGDILDKNLDLT
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEECCEECCCCCCC
GFECVIHEAAQINVRTSVEDPILDANINILGTINILEKMKEYGVKKIIFSSSGGAVYGEP
HHHHEEEHHHEEEEEECCCCCEEECCCEEEEHHHHHHHHHHCCCEEEEEECCCCEEECCC
KYLPVDEKHDVNPLSPYGLSKFCAEEYIKLYNRLYNIEYCILRYSNVYGKRQDPLGEAGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCCC
ISIFIDKMKKGESPIIYGNGNQTRDFVNVKDVSKANLMALNWKNEIVNIGSGKETSVNEL
CEEEEHHHHCCCCCEEECCCCCCCEEEECCCCCCCEEEEEECCCCEEECCCCCCCCHHHH
FKIISSEVGFDKNPIYEKERDGEVYRIYIDYNYAKSLGWIPEVEMDNGIKDI
HHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKILVTGGAGFIGSHIVDLLIENGHDVTILDNLSTGNEKNINNSAKFINGDILDKNLDLT
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEECCEECCCCCCC
GFECVIHEAAQINVRTSVEDPILDANINILGTINILEKMKEYGVKKIIFSSSGGAVYGEP
HHHHEEEHHHEEEEEECCCCCEEECCCEEEEHHHHHHHHHHCCCEEEEEECCCCEEECCC
KYLPVDEKHDVNPLSPYGLSKFCAEEYIKLYNRLYNIEYCILRYSNVYGKRQDPLGEAGV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCCC
ISIFIDKMKKGESPIIYGNGNQTRDFVNVKDVSKANLMALNWKNEIVNIGSGKETSVNEL
CEEEEHHHHCCCCCEEECCCCCCCEEEECCCCCCCEEEEEECCCCEEECCCCCCCCHHHH
FKIISSEVGFDKNPIYEKERDGEVYRIYIDYNYAKSLGWIPEVEMDNGIKDI
HHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]