Click here to switch to the map view.

The map label for this gene is pyrK [H]

Identifier: 150398967

GI number: 150398967

Start: 246031

End: 246801

Strand: Reverse

Name: pyrK [H]

Synonym: Mevan_0212

Alternate gene names: 150398967

Gene position: 246801-246031 (Counterclockwise)

Preceding gene: 150398968

Following gene: 150398966

Centisome position: 14.35

GC content: 35.28

Gene sequence:

>771_bases
ATGGAAAAACCCGTGATGTGTAGAATCATAGATATTAAAGAGGAAAGCCCGTCTGTAAAAACCTATTTTTTAGATAGGGA
TTTTGATTTTAAACCGGGACAATTTGGAATGGTGTGGATTCCAGGCGTAGATGAAAAGCCATTTGGATTTTCGAGTAAAA
ACTCAATAAGCGTTGCCATGGTTGGAGAATTTACAAAAAAGATGCATTCCTTAAAAATAGGGGATTTATTGGGGATTAGA
GGCCCATATGGAAATAATTTTGAAAGTATTGGTGACAAAATACTTGCAGTTTCAGGCGGAATTGGAAGTGCACCGATTAT
TTCCACAATTGAAGCATTTTCAAAACTTGGAATTTCAATAACATCTATAATTGGCGGTAGAACTAAAGAAGAACTTTTAT
TTTTGGAACGTTTCCAAAACTGCGGAACAGTTTACCCCTGTACTGATGACTGTAGTTTTGGGTTTCACGGGTTTACGACT
GAAAAAATGGAAGAACTACTTTCAAAAGAAAAATATGACATGATAATTACTTGCGGCCCTGAAATTATGATGAAAAAGGT
CATTAAAATTGCTGAAAAATATGATGTACCTGTTCAATTATCCTTGGAACGATACATGAAGTGCGGAATTGGAATATGTG
GTCAATGTGCGGTTGATAATGAAGGACTATGCATATGTAAAGATGGCCCGGTATTTTGGGATAACAAACTTAAATTTATT
TCCGAATTTGGAGAATATAAAAGGGATGCAAGTGGTGCAGTTTTTAGATAA

Upstream 100 bases:

>100_bases
TGGAAGGAAGGAACATAATTTTAATACCTTTTAATTTTAAAATATTTTTAATATTTAAAAGCTTACTTTTTTAAAAAAAT
TTAAAATTCAAGTGATAAGG

Downstream 100 bases:

>100_bases
TTTAATAATTTAATAATTAATTAGTTAATATTTAATAATGCATGAAAAGAAATAAAAATAAAAATACTTTTTTAAGTGTT
TAACGTGATTTAAAATGTGT

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEKPVMCRIIDIKEESPSVKTYFLDRDFDFKPGQFGMVWIPGVDEKPFGFSSKNSISVAMVGEFTKKMHSLKIGDLLGIR
GPYGNNFESIGDKILAVSGGIGSAPIISTIEAFSKLGISITSIIGGRTKEELLFLERFQNCGTVYPCTDDCSFGFHGFTT
EKMEELLSKEKYDMIITCGPEIMMKKVIKIAEKYDVPVQLSLERYMKCGIGICGQCAVDNEGLCICKDGPVFWDNKLKFI
SEFGEYKRDASGAVFR

Sequences:

>Translated_256_residues
MEKPVMCRIIDIKEESPSVKTYFLDRDFDFKPGQFGMVWIPGVDEKPFGFSSKNSISVAMVGEFTKKMHSLKIGDLLGIR
GPYGNNFESIGDKILAVSGGIGSAPIISTIEAFSKLGISITSIIGGRTKEELLFLERFQNCGTVYPCTDDCSFGFHGFTT
EKMEELLSKEKYDMIITCGPEIMMKKVIKIAEKYDVPVQLSLERYMKCGIGICGQCAVDNEGLCICKDGPVFWDNKLKFI
SEFGEYKRDASGAVFR
>Mature_256_residues
MEKPVMCRIIDIKEESPSVKTYFLDRDFDFKPGQFGMVWIPGVDEKPFGFSSKNSISVAMVGEFTKKMHSLKIGDLLGIR
GPYGNNFESIGDKILAVSGGIGSAPIISTIEAFSKLGISITSIIGGRTKEELLFLERFQNCGTVYPCTDDCSFGFHGFTT
EKMEELLSKEKYDMIITCGPEIMMKKVIKIAEKYDVPVQLSLERYMKCGIGICGQCAVDNEGLCICKDGPVFWDNKLKFI
SEFGEYKRDASGAVFR

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 28501; Mature: 28501

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPVMCRIIDIKEESPSVKTYFLDRDFDFKPGQFGMVWIPGVDEKPFGFSSKNSISVAM
CCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEE
VGEFTKKMHSLKIGDLLGIRGPYGNNFESIGDKILAVSGGIGSAPIISTIEAFSKLGISI
HHHHHHHHHHCCHHHHEECCCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEE
TSIIGGRTKEELLFLERFQNCGTVYPCTDDCSFGFHGFTTEKMEELLSKEKYDMIITCGP
EHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECH
EIMMKKVIKIAEKYDVPVQLSLERYMKCGIGICGQCAVDNEGLCICKDGPVFWDNKLKFI
HHHHHHHHHHHHHCCCCEEECHHHHHHCCCCCCCEEEECCCCEEEECCCCEEECCHHHHH
SEFGEYKRDASGAVFR
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKPVMCRIIDIKEESPSVKTYFLDRDFDFKPGQFGMVWIPGVDEKPFGFSSKNSISVAM
CCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEE
VGEFTKKMHSLKIGDLLGIRGPYGNNFESIGDKILAVSGGIGSAPIISTIEAFSKLGISI
HHHHHHHHHHCCHHHHEECCCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEE
TSIIGGRTKEELLFLERFQNCGTVYPCTDDCSFGFHGFTTEKMEELLSKEKYDMIITCGP
EHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECH
EIMMKKVIKIAEKYDVPVQLSLERYMKCGIGICGQCAVDNEGLCICKDGPVFWDNKLKFI
HHHHHHHHHHHHHCCCCEEECHHHHHHCCCCCCCEEEECCCCEEEECCCCEEECCHHHHH
SEFGEYKRDASGAVFR
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]