Click here to switch to the map view.

The map label for this gene is chvG [H]

Identifier: 150398443

GI number: 150398443

Start: 3431549

End: 3433285

Strand: Reverse

Name: chvG [H]

Synonym: Smed_3251

Alternate gene names: 150398443

Gene position: 3433285-3431549 (Counterclockwise)

Preceding gene: 150398444

Following gene: 150398442

Centisome position: 90.78

GC content: 63.27

Gene sequence:

>1737_bases
ATGCTGCGTGGGCAGCGACGATGGGCGCATCCCTTTACGCTGATCCGCCGCCTGTTCGGCAATGCCGTCTTTTCGAGCCT
TACGCGGCGCATCGTCTTCTTCAACCTGGTGGCGCTCGTGGTCCTCGTCGGCGGGATCATGTATCTCAACCAGTTCAGGG
AGGGCCTGATCGACGCGCGGGTCGAGAGCCTCCTGACTCAGGGCGAAATTATCGCCGGCGCCATTTCCGCCTCCGCATCG
GTCGATACCAATTCGATTACCATCGATCCGGAAAAGCTGCTCGAACTGCAAGCCGGCGAAAGCATCACGCCGCTGCCGAG
CGACGAAGACCTCGAATTCCCGATCATCCAGGAGCGCGTGGCACCGGTCTTGAGGCGGCTGATCTCGCCGACGCGCACCC
GAGCGCGCCTGTTCGACGCCGATGCCGACCTGCTGCTCGATTCCCGCCACCTCTATAGCGGCGGCCAGGTGCTCCGGTTC
GACCTGCCGCCGGTCGATCCGGAAAGTCCGAGTCTCGCCGATGAATTCGGTACCTGGTTCAACCGGCTGCTGCAGCCGGG
CGACCTGCCGCTCTACAAGGAGCCCCCCGGGGGCAATGGCTCGATTTATCCGGAAGTCATGAATGCCCTGACGGGCGTGC
GCGGCGCGGTCGTGCGGGTGACCGAGAAGGGCGAACTGATCGTTTCCGTGGCCGTTCCCGTGCAGCGCTTCCGCGCGGTG
CTCGGCGTGCTCCTCCTCTCGACACAGGCCGGCGATATCGACAAGATCGTCCACGCCGAACGGCTGGCGATTATCCGCGT
CTTCGGCGTGGCGGCGCTCGTCAACGTCATCCTTTCGCTGCTTCTCTCCTCGACGATCGCCAATCCGCTGCGGCGCCTTT
CGGCTGCGGCCATCCGCGTGCGCCGCGGCGGCGCCAAGGAACGGGAGGAGATTCCGGATTTCTCGTCCCGCCAGGACGAG
ATCGGCAATCTTTCCGTGGCGCTCCGGGAAATGACGACGGCGCTCTACGACCGGATCGCCGCGATCGAGAACTTCGCGGC
CGATGTGAGCCATGAGCTCAAGAATCCATTGACCTCGCTTCGCAGCGCCGTCGAAACCCTGCCGCTTGCGCGTAACGAGG
AATCGAAGAAACGACTGATGGACGTCATTCAGCACGACGTTCGGCGTCTCGACCGGCTGATAAGCGATATTTCCGATGCT
TCGCGCTTGGATGCGGAGCTTGCCCGCGCCGACGCGAAGAAAGTTGACCTCGAAAAACTCCTGGGCGACCTTGTCGAAAT
TTCCCGGCAGATCCGAGGCAGCAAGAAGCCGGTTCTGCTCGACTTCGTCGTCGACCGTAAGGACAATCCGCGCGCGAGCT
TCATCGTCAGCGGTCACGACCTGCGCATCGGCCAGATCATCACGAACCTGATCGAAAACGCCCGCTCCTTCGTTCCCGAA
CAGAACGGCCGCATCATCGTTCGGCTGACCCGCTCGCGGTCGCGCTGTCTCGTTTACGTCGAAGATAACGGTCCCGGCAT
CCAGGCGGAGGACATCGACCGCATCTTCGAGCGCTTCTACACCGACCGGCCGGAAGGCGAGGACTTCGGCCAGAACTCGG
GGCTTGGCCTTTCGATTTCGCGCCAGATTGCCGAGGCGCATGGCGGAACGTTGAGGGCCGAGAACATTACGGGCAAGGAC
GGCCATGTCAGCGGCGCCCGCTTCATTCTCTCACTGCCAGCCGAGCCGCACCCGTGA

Upstream 100 bases:

>100_bases
GGAAACACGCGAATGCGGCAGTGAAGGCCGCGGCGCGGGAGCGGGAGACTTGGTGGAAGTCTGGCAGGGCGATATCGAAG
AAGCTGAAGGACGGACATCG

Downstream 100 bases:

>100_bases
ATACGCCCGTATGCAATGTGCACGGAACGGCTATCGTTCTCGGCACGACCGGGCTGCTGATCACCGGGCCTTCCGGATTG
GGCAAGTCGGCACTCGCACT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MLRGQRRWAHPFTLIRRLFGNAVFSSLTRRIVFFNLVALVVLVGGIMYLNQFREGLIDARVESLLTQGEIIAGAISASAS
VDTNSITIDPEKLLELQAGESITPLPSDEDLEFPIIQERVAPVLRRLISPTRTRARLFDADADLLLDSRHLYSGGQVLRF
DLPPVDPESPSLADEFGTWFNRLLQPGDLPLYKEPPGGNGSIYPEVMNALTGVRGAVVRVTEKGELIVSVAVPVQRFRAV
LGVLLLSTQAGDIDKIVHAERLAIIRVFGVAALVNVILSLLLSSTIANPLRRLSAAAIRVRRGGAKEREEIPDFSSRQDE
IGNLSVALREMTTALYDRIAAIENFAADVSHELKNPLTSLRSAVETLPLARNEESKKRLMDVIQHDVRRLDRLISDISDA
SRLDAELARADAKKVDLEKLLGDLVEISRQIRGSKKPVLLDFVVDRKDNPRASFIVSGHDLRIGQIITNLIENARSFVPE
QNGRIIVRLTRSRSRCLVYVEDNGPGIQAEDIDRIFERFYTDRPEGEDFGQNSGLGLSISRQIAEAHGGTLRAENITGKD
GHVSGARFILSLPAEPHP

Sequences:

>Translated_578_residues
MLRGQRRWAHPFTLIRRLFGNAVFSSLTRRIVFFNLVALVVLVGGIMYLNQFREGLIDARVESLLTQGEIIAGAISASAS
VDTNSITIDPEKLLELQAGESITPLPSDEDLEFPIIQERVAPVLRRLISPTRTRARLFDADADLLLDSRHLYSGGQVLRF
DLPPVDPESPSLADEFGTWFNRLLQPGDLPLYKEPPGGNGSIYPEVMNALTGVRGAVVRVTEKGELIVSVAVPVQRFRAV
LGVLLLSTQAGDIDKIVHAERLAIIRVFGVAALVNVILSLLLSSTIANPLRRLSAAAIRVRRGGAKEREEIPDFSSRQDE
IGNLSVALREMTTALYDRIAAIENFAADVSHELKNPLTSLRSAVETLPLARNEESKKRLMDVIQHDVRRLDRLISDISDA
SRLDAELARADAKKVDLEKLLGDLVEISRQIRGSKKPVLLDFVVDRKDNPRASFIVSGHDLRIGQIITNLIENARSFVPE
QNGRIIVRLTRSRSRCLVYVEDNGPGIQAEDIDRIFERFYTDRPEGEDFGQNSGLGLSISRQIAEAHGGTLRAENITGKD
GHVSGARFILSLPAEPHP
>Mature_578_residues
MLRGQRRWAHPFTLIRRLFGNAVFSSLTRRIVFFNLVALVVLVGGIMYLNQFREGLIDARVESLLTQGEIIAGAISASAS
VDTNSITIDPEKLLELQAGESITPLPSDEDLEFPIIQERVAPVLRRLISPTRTRARLFDADADLLLDSRHLYSGGQVLRF
DLPPVDPESPSLADEFGTWFNRLLQPGDLPLYKEPPGGNGSIYPEVMNALTGVRGAVVRVTEKGELIVSVAVPVQRFRAV
LGVLLLSTQAGDIDKIVHAERLAIIRVFGVAALVNVILSLLLSSTIANPLRRLSAAAIRVRRGGAKEREEIPDFSSRQDE
IGNLSVALREMTTALYDRIAAIENFAADVSHELKNPLTSLRSAVETLPLARNEESKKRLMDVIQHDVRRLDRLISDISDA
SRLDAELARADAKKVDLEKLLGDLVEISRQIRGSKKPVLLDFVVDRKDNPRASFIVSGHDLRIGQIITNLIENARSFVPE
QNGRIIVRLTRSRSRCLVYVEDNGPGIQAEDIDRIFERFYTDRPEGEDFGQNSGLGLSISRQIAEAHGGTLRAENITGKD
GHVSGARFILSLPAEPHP

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=261, Percent_Identity=29.5019157088123, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790346, Length=306, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787894, Length=288, Percent_Identity=28.4722222222222, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=27.0161290322581, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=27.710843373494, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=27.8969957081545, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789403, Length=278, Percent_Identity=28.0575539568345, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=23.8866396761134, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=290, Percent_Identity=26.2068965517241, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=28.5198555956679, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=28.5123966942149, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=27.3504273504274, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63866; Mature: 63866

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGQRRWAHPFTLIRRLFGNAVFSSLTRRIVFFNLVALVVLVGGIMYLNQFREGLIDAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VESLLTQGEIIAGAISASASVDTNSITIDPEKLLELQAGESITPLPSDEDLEFPIIQERV
HHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
APVLRRLISPTRTRARLFDADADLLLDSRHLYSGGQVLRFDLPPVDPESPSLADEFGTWF
HHHHHHHHCCHHHHHHHHCCCHHHHCCCCHHCCCCCEEEECCCCCCCCCCCHHHHHHHHH
NRLLQPGDLPLYKEPPGGNGSIYPEVMNALTGVRGAVVRVTEKGELIVSVAVPVQRFRAV
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHH
LGVLLLSTQAGDIDKIVHAERLAIIRVFGVAALVNVILSLLLSSTIANPLRRLSAAAIRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGGAKEREEIPDFSSRQDEIGNLSVALREMTTALYDRIAAIENFAADVSHELKNPLTSL
HCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAVETLPLARNEESKKRLMDVIQHDVRRLDRLISDISDASRLDAELARADAKKVDLEKL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDLVEISRQIRGSKKPVLLDFVVDRKDNPRASFIVSGHDLRIGQIITNLIENARSFVPE
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCC
QNGRIIVRLTRSRSRCLVYVEDNGPGIQAEDIDRIFERFYTDRPEGEDFGQNSGLGLSIS
CCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
RQIAEAHGGTLRAENITGKDGHVSGARFILSLPAEPHP
HHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MLRGQRRWAHPFTLIRRLFGNAVFSSLTRRIVFFNLVALVVLVGGIMYLNQFREGLIDAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VESLLTQGEIIAGAISASASVDTNSITIDPEKLLELQAGESITPLPSDEDLEFPIIQERV
HHHHHHCCCHHHHHHHCCCCCCCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
APVLRRLISPTRTRARLFDADADLLLDSRHLYSGGQVLRFDLPPVDPESPSLADEFGTWF
HHHHHHHHCCHHHHHHHHCCCHHHHCCCCHHCCCCCEEEECCCCCCCCCCCHHHHHHHHH
NRLLQPGDLPLYKEPPGGNGSIYPEVMNALTGVRGAVVRVTEKGELIVSVAVPVQRFRAV
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHH
LGVLLLSTQAGDIDKIVHAERLAIIRVFGVAALVNVILSLLLSSTIANPLRRLSAAAIRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRGGAKEREEIPDFSSRQDEIGNLSVALREMTTALYDRIAAIENFAADVSHELKNPLTSL
HCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAVETLPLARNEESKKRLMDVIQHDVRRLDRLISDISDASRLDAELARADAKKVDLEKL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDLVEISRQIRGSKKPVLLDFVVDRKDNPRASFIVSGHDLRIGQIITNLIENARSFVPE
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCC
QNGRIIVRLTRSRSRCLVYVEDNGPGIQAEDIDRIFERFYTDRPEGEDFGQNSGLGLSIS
CCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
RQIAEAHGGTLRAENITGKDGHVSGARFILSLPAEPHP
HHHHHHCCCEEEECCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]