BacMap

Definition	Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession	NC_009636
Length	3,781,904

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The map label for this gene is fabG [H]

Identifier: 150398357

GI number: 150398357

Start: 3326566

End: 3327339

Strand: Reverse

Name: fabG [H]

Synonym: Smed_3165

Alternate gene names: 150398357

Gene position: 3327339-3326566 (Counterclockwise)

Preceding gene: 150398358

Following gene: 150398356

Centisome position: 87.98

GC content: 65.5

Gene sequence:

>774_bases
ATGACCGAGAAGGCACGCCCCGTCGCGATCGTCACCGGCGGCCGCCGAGGCATCGGGCTCGGCATTGCCCGGGCGCTCGC
GGTGAGCGGCTTCGACATCGCCATCACCGGCATCGGCGATGCGGAGGGTGTCGCTCCCGTAATCGCCGAACTTGGCATGC
TCGGCGCCCGGGTGATCTTCCAGCGCGCCGACCTAGCCGACCTTTCGGGCCATCAGGCGACCTTAGATGCGGTTGTCGCC
GAATTCGGCCGGATCGACTGCCTCGTCAACAATGCCGGGATCGCTCCCGTCGTTCGCGGCGATTTTCTCGATCTGAAGCC
GGAGAACTTCGACACGATCATCGGCGTCAATCTGCGCGGCACGGTGTTTTTCACGCAGGTCGTGCTGAAGGCCATGCTGG
CGGGCGAGGCTCAATCGCCGCGTTCGATCGTCAACATCACCTCGGTTTCCGCCGCGATGACATCGCCCGAACGGCTCGAC
TACTGCATGAGCAAGGCGGGGCTCGCCTCCTTCAGCCAGGGCTTGGCGCTGAGGCTCGCCGAGACAGGCATCGCCGTCTT
CGAGGTCCGCCCCGGCATCATCCGCTCCGACATGACGGCTGGCGTTTCCAGCAAATATGACGGGCTGATTGCGGACGGGC
TGGTGCCTATGCGGCGCTGGGGGGAGCCCGGCGACATCGGGGATATCGTCGCGGGCCTCGCCAGCGGAAAATTCGGCTTC
GCCACCGGCTCGGTCATCCAGGCTGATGGGGGTTTATCGATCGGTCGGCTGTGA

Upstream 100 bases:

>100_bases
CCAGCTGCCTGCCGACCTCGGCCGCCGTCAATCCGGCGCTGACGGTCGCGGCCCAGGCGCTGCGCGTTGCGGACCATATC
GTGAAACAGGACCTGCGATC

Downstream 100 bases:

>100_bases
AACTGCCCTCTCCGGTTGTGAGATTTTCCCCTCTCCTCGGGTTCAACCCGAGAATTAGCCTTCTCCCCGGTCGCGGGTAG
AGGGGACGTGGCTGACGCGC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTEKARPVAIVTGGRRGIGLGIARALAVSGFDIAITGIGDAEGVAPVIAELGMLGARVIFQRADLADLSGHQATLDAVVA
EFGRIDCLVNNAGIAPVVRGDFLDLKPENFDTIIGVNLRGTVFFTQVVLKAMLAGEAQSPRSIVNITSVSAAMTSPERLD
YCMSKAGLASFSQGLALRLAETGIAVFEVRPGIIRSDMTAGVSSKYDGLIADGLVPMRRWGEPGDIGDIVAGLASGKFGF
ATGSVIQADGGLSIGRL

Sequences:

>Translated_257_residues
MTEKARPVAIVTGGRRGIGLGIARALAVSGFDIAITGIGDAEGVAPVIAELGMLGARVIFQRADLADLSGHQATLDAVVA
EFGRIDCLVNNAGIAPVVRGDFLDLKPENFDTIIGVNLRGTVFFTQVVLKAMLAGEAQSPRSIVNITSVSAAMTSPERLD
YCMSKAGLASFSQGLALRLAETGIAVFEVRPGIIRSDMTAGVSSKYDGLIADGLVPMRRWGEPGDIGDIVAGLASGKFGF
ATGSVIQADGGLSIGRL
>Mature_256_residues
TEKARPVAIVTGGRRGIGLGIARALAVSGFDIAITGIGDAEGVAPVIAELGMLGARVIFQRADLADLSGHQATLDAVVAE
FGRIDCLVNNAGIAPVVRGDFLDLKPENFDTIIGVNLRGTVFFTQVVLKAMLAGEAQSPRSIVNITSVSAAMTSPERLDY
CMSKAGLASFSQGLALRLAETGIAVFEVRPGIIRSDMTAGVSSKYDGLIADGLVPMRRWGEPGDIGDIVAGLASGKFGFA
TGSVIQADGGLSIGRL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=31.1023622047244, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=29.8387096774194, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=32.8205128205128, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=28.5140562248996, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=26.4822134387352, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=27.8606965174129, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=27.7992277992278, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI186928839, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI59889578, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=29.2, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=35.3413654618474, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=32.5301204819277, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.7086614173228, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=32.9268292682927, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=29.1497975708502, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=28.6885245901639, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=27.5303643724696, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=29.0076335877863, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=27.979274611399, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=31.3725490196078, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=29.6442687747036, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=30.7407407407407, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.9236947791165, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=30.9236947791165, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=31.5589353612167, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.1044776119403, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=29.1512915129151, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.0566037735849, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=29.6577946768061, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=30.6513409961686, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=29.5620437956204, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=28.6259541984733, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.6992481203008, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=26.8482490272374, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.9212598425197, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=27.5735294117647, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=27.7372262773723, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=28.4090909090909, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=30.5882352941176, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=27.3809523809524, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=34.1269841269841, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=30.6451612903226, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=32.03125, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=31.3953488372093, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=28.6821705426357, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=259, Percent_Identity=32.046332046332, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=29.1828793774319, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644337, Length=177, Percent_Identity=31.0734463276836, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26503; Mature: 26372

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKARPVAIVTGGRRGIGLGIARALAVSGFDIAITGIGDAEGVAPVIAELGMLGARVIF
CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
QRADLADLSGHQATLDAVVAEFGRIDCLVNNAGIAPVVRGDFLDLKPENFDTIIGVNLRG
HHCCHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCEEECCCCCCCEEEEECCCC
TVFFTQVVLKAMLAGEAQSPRSIVNITSVSAAMTSPERLDYCMSKAGLASFSQGLALRLA
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEE
ETGIAVFEVRPGIIRSDMTAGVSSKYDGLIADGLVPMRRWGEPGDIGDIVAGLASGKFGF
CCCEEEEEECCCHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCCCHHHHHHHHHCCCCCC
ATGSVIQADGGLSIGRL
CCCCEEEECCCEECCCC
>Mature Secondary Structure 
TEKARPVAIVTGGRRGIGLGIARALAVSGFDIAITGIGDAEGVAPVIAELGMLGARVIF
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
QRADLADLSGHQATLDAVVAEFGRIDCLVNNAGIAPVVRGDFLDLKPENFDTIIGVNLRG
HHCCHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCEEEECCEEECCCCCCCEEEEECCCC
TVFFTQVVLKAMLAGEAQSPRSIVNITSVSAAMTSPERLDYCMSKAGLASFSQGLALRLA
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEE
ETGIAVFEVRPGIIRSDMTAGVSSKYDGLIADGLVPMRRWGEPGDIGDIVAGLASGKFGF
CCCEEEEEECCCHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCCCHHHHHHHHHCCCCCC
ATGSVIQADGGLSIGRL
CCCCEEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA