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The map label for this gene is aatB [H]

Identifier: 150398352

GI number: 150398352

Start: 3319895

End: 3321127

Strand: Direct

Name: aatB [H]

Synonym: Smed_3160

Alternate gene names: 150398352

Gene position: 3319895-3321127 (Clockwise)

Preceding gene: 150398351

Following gene: 150398354

Centisome position: 87.78

GC content: 63.18

Gene sequence:

>1233_bases
ATGACCATCAATGCAACGGTCAAGGAGGCGGGCTTCCGGCCCGCCTCGCGGATTTCTTCGATCGGCGTTTCGGAAATCCT
GAAGATCGGCGCCCGCGCCGCCGCCATGAAGCGCGAAGGCAAGCCGGTGATCATTCTCGGCGCCGGCGAGCCGGATTTCG
ACACGCCGGACCACGTGAAGCAAGCCGCCTCGGACGCGATCCATCGCGGCGAGACGAAATATACCGCACTCGACGGCACG
CCGGAATTGAAGAAGGCGATACGCGAAAAATTCCAGCGTGAGAACGGGCTAGCCTACGAGCTCGACGAAATCACGGTTGC
CACCGGCGCCAAACAGATCCTGTTCAATGCCATGATGGCGTCGCTCGATCCCGGCGACGAGGTGGTCATTCCGACGCCCT
ATTGGACCTCCTATTCGGATATCGTCCAGATCTGCGAGGGCAAGCCGATCCTGATTGCATGCGACGCATCTTCCGGCTTC
CGCCTGACGGCGCAAAAGCTGGAAGCGGCGATCACGCCTCGGACGAGGTGGGTGCTCCTGAACTCGCCCTCGAACCCCTC
CGGCGCCGCCTACAGCGCGGCCGACTACCGGCCTCTGCTCGACGTGCTGCTCAAGCACCCGCATGTCTGGCTGCTCGTCG
ATGATATGTACGAGCACATCGTCTATGACGCTTTCCGCTTCGTCACGCCGGCTCGGCTCGAGCCGGGCCTCAAGGATCGG
ACGCTCACCGTCAACGGCGTCTCGAAGGCCTATGCGATGACGGGCTGGCGGATCGGCTATGCCGGGGGCCCGCGCGCGCT
CATCAAGGCGATGGCCGTCGTCCAGAGCCAGGCGACCTCCTGTCCCTCTTCGGTAAGCCAGGCGGCTTCGGTCGCGGCGC
TCAACGGACCGCAGGACTTTCTGAAAGAACGGACCGAAAGCTTCCAACGCCGCCGCAATCTCGTGGTCAACGGGCTGAAT
GCGATCGAAGGGCTCGACTGCCGCGTTCCCGAAGGCGCCTTCTACACCTTCTCCGGCTGTGCCGGCGTGCTCGGCAGGGT
GACGCCATCAGGCAAAAGGATCGAGTCGGACACGGACTTCTGCGCCTACCTTCTGGAAGACTCCCACGTCGCCGTCGTCC
CGGGCTCGGCCTTCGGCCTCTCCCCTTATTTCCGCATCTCCTATGCGACCTCGGAGGCGGAACTGAAGGAAGCGCTTGAA
CGCATTTCGGCAGCATGCAAGCGGCTGTCATAA

Upstream 100 bases:

>100_bases
GCCTATATGCGACGCGCCACAAATACGGTGAACTATTCCAAGGCTCTGCCGCTGGCGCAGGGCGTCTCTTTCGACATCGA
ATAATCGAACAGGATCGGCC

Downstream 100 bases:

>100_bases
GTCTACACCGCGTTTAAGAGGACTCGGGCGGCGCGGCTCCTATCCGATGCCCGGTGACTTGAAACGACCCCTCATCCGGC
CCGCCGGCCGGTTGAGGGGC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTINATVKEAGFRPASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVKQAASDAIHRGETKYTALDGT
PELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVVIPTPYWTSYSDIVQICEGKPILIACDASSGF
RLTAQKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDR
TLTVNGVSKAYAMTGWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDFLKERTESFQRRRNLVVNGLN
AIEGLDCRVPEGAFYTFSGCAGVLGRVTPSGKRIESDTDFCAYLLEDSHVAVVPGSAFGLSPYFRISYATSEAELKEALE
RISAACKRLS

Sequences:

>Translated_410_residues
MTINATVKEAGFRPASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVKQAASDAIHRGETKYTALDGT
PELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVVIPTPYWTSYSDIVQICEGKPILIACDASSGF
RLTAQKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDR
TLTVNGVSKAYAMTGWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDFLKERTESFQRRRNLVVNGLN
AIEGLDCRVPEGAFYTFSGCAGVLGRVTPSGKRIESDTDFCAYLLEDSHVAVVPGSAFGLSPYFRISYATSEAELKEALE
RISAACKRLS
>Mature_409_residues
TINATVKEAGFRPASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVKQAASDAIHRGETKYTALDGTP
ELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVVIPTPYWTSYSDIVQICEGKPILIACDASSGFR
LTAQKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDRT
LTVNGVSKAYAMTGWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDFLKERTESFQRRRNLVVNGLNA
IEGLDCRVPEGAFYTFSGCAGVLGRVTPSGKRIESDTDFCAYLLEDSHVAVVPGSAFGLSPYFRISYATSEAELKEALER
ISAACKRLS

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=26.8542199488491, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=26.8542199488491, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=26.4631043256997, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=26.4631043256997, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=24.5033112582781, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=22.8346456692913, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI215599424, Length=357, Percent_Identity=22.96918767507, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI19263340, Length=357, Percent_Identity=22.96918767507, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786816, Length=396, Percent_Identity=27.7777777777778, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788627, Length=369, Percent_Identity=28.7262872628726, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788722, Length=420, Percent_Identity=27.1428571428571, Blast_Score=134, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=356, Percent_Identity=24.438202247191, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=389, Percent_Identity=24.4215938303342, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=389, Percent_Identity=24.4215938303342, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=411, Percent_Identity=25.3041362530414, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=366, Percent_Identity=22.4043715846995, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=24.4274809160305, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6323118, Length=348, Percent_Identity=23.5632183908046, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=345, Percent_Identity=22.3188405797101, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573069, Length=396, Percent_Identity=24.2424242424242, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646114, Length=396, Percent_Identity=24.2424242424242, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573067, Length=396, Percent_Identity=24.2424242424242, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573065, Length=396, Percent_Identity=24.2424242424242, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18859735, Length=381, Percent_Identity=23.0971128608924, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24641770, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641760, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641768, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641766, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641764, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45551451, Length=398, Percent_Identity=25.6281407035176, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44397; Mature: 44266

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINATVKEAGFRPASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVK
CCCCCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
QAASDAIHRGETKYTALDGTPELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMA
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHH
SLDPGDEVVIPTPYWTSYSDIVQICEGKPILIACDASSGFRLTAQKLEAAITPRTRWVLL
HCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCEEEEEE
NSPSNPSGAAYSAADYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDR
ECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHCCCCCCCC
TLTVNGVSKAYAMTGWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDF
EEEECCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
LKERTESFQRRRNLVVNGLNAIEGLDCRVPEGAFYTFSGCAGVLGRVTPSGKRIESDTDF
HHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCHH
CAYLLEDSHVAVVPGSAFGLSPYFRISYATSEAELKEALERISAACKRLS
HHHEECCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TINATVKEAGFRPASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPDHVK
CCCCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
QAASDAIHRGETKYTALDGTPELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMA
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHH
SLDPGDEVVIPTPYWTSYSDIVQICEGKPILIACDASSGFRLTAQKLEAAITPRTRWVLL
HCCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCEEEEEE
NSPSNPSGAAYSAADYRPLLDVLLKHPHVWLLVDDMYEHIVYDAFRFVTPARLEPGLKDR
ECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHCCCCCCCC
TLTVNGVSKAYAMTGWRIGYAGGPRALIKAMAVVQSQATSCPSSVSQAASVAALNGPQDF
EEEECCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
LKERTESFQRRRNLVVNGLNAIEGLDCRVPEGAFYTFSGCAGVLGRVTPSGKRIESDTDF
HHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCHH
CAYLLEDSHVAVVPGSAFGLSPYFRISYATSEAELKEALERISAACKRLS
HHHEECCCEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]