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The map label for this gene is ffh [H]

Identifier: 150398289

GI number: 150398289

Start: 3242073

End: 3243617

Strand: Direct

Name: ffh [H]

Synonym: Smed_3095

Alternate gene names: 150398289

Gene position: 3242073-3243617 (Clockwise)

Preceding gene: 150398282

Following gene: 150398290

Centisome position: 85.73

GC content: 64.92

Gene sequence:

>1545_bases
ATGTTCGAGAGCCTCCAGGACCGTCTTGGTTCCATACTGAATGGACTGACCGGCCGCGGCGCCCTGTCGGAAGCCGATGT
TTCCGCAGCGCTTCGGGAGGTTCGCCGTGCGCTGCTCGAAGCGGACGTCGCACTCGACGTCGTGCGGTCCTTCACGGAAA
AGGTTCGTGAGAAGGCGGTCGGCGCCGAAATCGTCAAGTCGATCAAGCCCGGCCAGATGGTCGTCAAGATCGTTCATGAC
GAGCTCGTGGCGATGCTCGGATCCGAGGGCGTCACGATCGATCTCAACGCTCCGGCTCCCGTCGTTATCATGATGGTGGG
CCTGCAGGGCTCGGGCAAGACCACGACGACCGGCAAAATCGCCAAGCGGCTGACCGCGCGGGACAAGAAGAAGGTCCTGA
TGGCCTCGCTCGATACCCGCCGCCCGGCCGCGCAGGAGCAGTTGCGCCAGCTCGGCGTGCAGACGGGGGTCGACACGCTG
CCGATCATTGCCGGCCAGTCGCCGACCGATATCGCCGCGCGCGCGGTACAGGCGGCCAAGCTCGGCGGCCACGATATCGT
CATCCTCGACACAGCCGGACGCACCCATATCGACGAGCCGTTGATGATGGAGATGGCGGAGATCAAGCGGAAATCCAGCC
CGCACGAAATCCTGCTCGTCGCCGATGCGCTGACGGGCCAGGACGCCGTCAATCTCGCCCGCAGCTTCGATGAACGCGTC
GGCATCACCGGCCTGGTCCTGACCCGTATGGACGGCGACGGCCGCGGCGGTGCGGCGCTCTCCATGCGTGCCATCACCGG
CAAGCCGATCAAGCTCATCGGCGTCGGCGAAAAGATGGACGAACTCGAGGAGTTCCACCCCCGCCGCGTCGCCGACCGGA
TACTCGGCATGGGCGACATCGTCTCGCTGGTCGAAAAGGCGGCGGAGAACATCGACGCCGAAAAGGCGGCGGCCATGGCC
GCCAAGATGGCCAAAGGCAAGTTCGACCTCAACGACCTCGCCGATCAGCTGCAGCAGATGCAGAAGATGGGCGGCATGGG
CGGCATCATGGGGCTGATGCCCGGCATGGCCGGCATGAAGGACAAGATGTCCGCCGCCGGCCTGGATGACAAGCTCTTCA
AGCGCCAGATCGCGATCATATCGTCCATGACCAGGACCGAGCGCGCCAATCCGGACATCCTCAAGCATTCGCGCAAGAAG
CGCATCGCCAGCGGCTCCGGCACCGATGCCTCCGACATCAACAAGCTTCTGAAGATGCACCGCCAGATGGCGGACATGAT
GAAGATGATGGGCGGCAAGGGCAAGGGCGGCATGATGAAGCAGATGATGGGTGGCCTTGCCGGCAAGATGGGGCTTGGCG
GCCTCGGTGGCGGCATGCCGGATCTGTCGAAGCTCGACCCGAAGCAACTCGAGGCCCTGCAGAAGCAGGCCGAAGCCGCC
GGCCTCGGCAAGCCCGGCGGTGGCTTGCCTGGCCTTGGTGGCGGTGGATTGCCGGGCCTGGGAGGCGGTTTCCCCGGTCT
CCCCGGCCTGCCGAAAAAGAAGTGA

Upstream 100 bases:

>100_bases
TCGGGTGGTTTTTGGCTTTGCGCCTTGTTTTCCGCGCGAAGGGACCCACGTTTTCGGACGAGCCGTGCTATGGCAATCCG
GAGACAAGAAGGAAGAGAAT

Downstream 100 bases:

>100_bases
GGATCGCGACGAATGCTTGATCCCGGGATCAAAGAGGAATTGGCGAGCTACCGGCAATCGATCGACAATATCGATGCCGC
GCTCGTCCACATGCTGGCCG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MFESLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTEKVREKAVGAEIVKSIKPGQMVVKIVHD
ELVAMLGSEGVTIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTARDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDIVILDTAGRTHIDEPLMMEMAEIKRKSSPHEILLVADALTGQDAVNLARSFDERV
GITGLVLTRMDGDGRGGAALSMRAITGKPIKLIGVGEKMDELEEFHPRRVADRILGMGDIVSLVEKAAENIDAEKAAAMA
AKMAKGKFDLNDLADQLQQMQKMGGMGGIMGLMPGMAGMKDKMSAAGLDDKLFKRQIAIISSMTRTERANPDILKHSRKK
RIASGSGTDASDINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGGMPDLSKLDPKQLEALQKQAEAA
GLGKPGGGLPGLGGGGLPGLGGGFPGLPGLPKKK

Sequences:

>Translated_514_residues
MFESLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTEKVREKAVGAEIVKSIKPGQMVVKIVHD
ELVAMLGSEGVTIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTARDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDIVILDTAGRTHIDEPLMMEMAEIKRKSSPHEILLVADALTGQDAVNLARSFDERV
GITGLVLTRMDGDGRGGAALSMRAITGKPIKLIGVGEKMDELEEFHPRRVADRILGMGDIVSLVEKAAENIDAEKAAAMA
AKMAKGKFDLNDLADQLQQMQKMGGMGGIMGLMPGMAGMKDKMSAAGLDDKLFKRQIAIISSMTRTERANPDILKHSRKK
RIASGSGTDASDINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGGMPDLSKLDPKQLEALQKQAEAA
GLGKPGGGLPGLGGGGLPGLGGGFPGLPGLPKKK
>Mature_514_residues
MFESLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTEKVREKAVGAEIVKSIKPGQMVVKIVHD
ELVAMLGSEGVTIDLNAPAPVVIMMVGLQGSGKTTTTGKIAKRLTARDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTL
PIIAGQSPTDIAARAVQAAKLGGHDIVILDTAGRTHIDEPLMMEMAEIKRKSSPHEILLVADALTGQDAVNLARSFDERV
GITGLVLTRMDGDGRGGAALSMRAITGKPIKLIGVGEKMDELEEFHPRRVADRILGMGDIVSLVEKAAENIDAEKAAAMA
AKMAKGKFDLNDLADQLQQMQKMGGMGGIMGLMPGMAGMKDKMSAAGLDDKLFKRQIAIISSMTRTERANPDILKHSRKK
RIASGSGTDASDINKLLKMHRQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGGMPDLSKLDPKQLEALQKQAEAA
GLGKPGGGLPGLGGGGLPGLGGGFPGLPGLPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=447, Percent_Identity=33.5570469798658, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI226371618, Length=392, Percent_Identity=33.6734693877551, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI23308697, Length=311, Percent_Identity=29.903536977492, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI295424842, Length=311, Percent_Identity=29.903536977492, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI89061728, Length=142, Percent_Identity=36.6197183098592, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=52.9137529137529, Blast_Score=440, Evalue=1e-124,
Organism=Escherichia coli, GI1789874, Length=254, Percent_Identity=37.007874015748, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=423, Percent_Identity=30.7328605200946, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=31.8791946308725, Blast_Score=115, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=490, Percent_Identity=31.0204081632653, Blast_Score=216, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6320498, Length=318, Percent_Identity=26.7295597484277, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647949, Length=446, Percent_Identity=31.390134529148, Blast_Score=198, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24641198, Length=319, Percent_Identity=28.8401253918495, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53996; Mature: 53996

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTEKVREKAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEIVKSIKPGQMVVKIVHDELVAMLGSEGVTIDLNAPAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHH
AKRLTARDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTLPIIAGQSPTDIAARAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
LGGHDIVILDTAGRTHIDEPLMMEMAEIKRKSSPHEILLVADALTGQDAVNLARSFDERV
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAITGKPIKLIGVGEKMDELEEFHPRRVADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCHHHHHHHHHCHHHH
VSLVEKAAENIDAEKAAAMAAKMAKGKFDLNDLADQLQQMQKMGGMGGIMGLMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCH
DKMSAAGLDDKLFKRQIAIISSMTRTERANPDILKHSRKKRIASGSGTDASDINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGGMPDLSKLDPKQLEALQKQAEAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHC
GLGKPGGGLPGLGGGGLPGLGGGFPGLPGLPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFESLQDRLGSILNGLTGRGALSEADVSAALREVRRALLEADVALDVVRSFTEKVREKAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEIVKSIKPGQMVVKIVHDELVAMLGSEGVTIDLNAPAPVVIMMVGLQGSGKTTTTGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCHHHHH
AKRLTARDKKKVLMASLDTRRPAAQEQLRQLGVQTGVDTLPIIAGQSPTDIAARAVQAAK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
LGGHDIVILDTAGRTHIDEPLMMEMAEIKRKSSPHEILLVADALTGQDAVNLARSFDERV
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAITGKPIKLIGVGEKMDELEEFHPRRVADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCHHHHHHHHHCHHHH
VSLVEKAAENIDAEKAAAMAAKMAKGKFDLNDLADQLQQMQKMGGMGGIMGLMPGMAGMK
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCH
DKMSAAGLDDKLFKRQIAIISSMTRTERANPDILKHSRKKRIASGSGTDASDINKLLKMH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKMMGGKGKGGMMKQMMGGLAGKMGLGGLGGGMPDLSKLDPKQLEALQKQAEAA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHC
GLGKPGGGLPGLGGGGLPGLGGGFPGLPGLPKKK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA