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The map label for this gene is cycY [H]

Identifier: 150398282

GI number: 150398282

Start: 3234967

End: 3235566

Strand: Direct

Name: cycY [H]

Synonym: Smed_3088

Alternate gene names: 150398282

Gene position: 3234967-3235566 (Clockwise)

Preceding gene: 150398281

Following gene: 150398289

Centisome position: 85.54

GC content: 63.17

Gene sequence:

>600_bases
ATGACGAACGCGCGGGACGAACGTGCGCCAGGCGCTATTCGCTATCTCGTGGCGGCGCTTCCGCTCCTGATCTTTGCGGT
TCTCGCACTCATCTTCTGGAGCCAATTGAACTCCGGCAGGGACGTCAGCGAAATACCCTCGGCCTTGATCGGGACCAAGG
CGCCGACGCTCGACATGCCGCGGCTTGAAGGCGCGGTGGCTCCGTCCGGCCGACCGATGCCGGCGCTTACCGATACGGCC
GTCAAGGGCAAGCTTACGCTCGTCAATGTCTGGGCCTCCTGGTGCGTGCCCTGCCGGCAGGAACATCCCGTCATTCTTGC
ATTGTCGAAAGACCCGCGCCTGACCGTCGTCGGCATCAACTACAAGGACCGGAACGAGAACGCGCTGAGGTTCCTCGGCG
AACTCGGCAACCCCTTCTCGGCGATCGGCGTCGATCCGAACGGTAAGGCAGCGATAGACTGGGGCGTTTACGGCATCCCG
GAATCATTCCTAGTCGCCGCCGATGGGACGATCCTCTACAAGCGTGCCGGGCCCTTCGACGAGAAGAGCCTCAGGGAAGG
GCTGCTGCCGGCGATCGAAAAAGCGCTTGCCGGGTCGTAG

Upstream 100 bases:

>100_bases
GGGTCCTAACCGATGGCCGTGCCCGTAAGCGCGAGCTGGAGCAGCTCGAAGCGGCCGGCATCCGCCGCCGTTCGGCGGAA
GCTTCGACCGGGGGGGGCAG

Downstream 100 bases:

>100_bases
CCCTCATCCGGCCTGCCACGCCTTCACCGCATCCATCGGCCACACCAGCATCAGCACGTTGAGCGTCAGATTGTCGCGCA
CCATAAAGCCGGTGAAGAGT

Product: periplasmic protein thiol--disulfide oxidoreductase DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTNARDERAPGAIRYLVAALPLLIFAVLALIFWSQLNSGRDVSEIPSALIGTKAPTLDMPRLEGAVAPSGRPMPALTDTA
VKGKLTLVNVWASWCVPCRQEHPVILALSKDPRLTVVGINYKDRNENALRFLGELGNPFSAIGVDPNGKAAIDWGVYGIP
ESFLVAADGTILYKRAGPFDEKSLREGLLPAIEKALAGS

Sequences:

>Translated_199_residues
MTNARDERAPGAIRYLVAALPLLIFAVLALIFWSQLNSGRDVSEIPSALIGTKAPTLDMPRLEGAVAPSGRPMPALTDTA
VKGKLTLVNVWASWCVPCRQEHPVILALSKDPRLTVVGINYKDRNENALRFLGELGNPFSAIGVDPNGKAAIDWGVYGIP
ESFLVAADGTILYKRAGPFDEKSLREGLLPAIEKALAGS
>Mature_198_residues
TNARDERAPGAIRYLVAALPLLIFAVLALIFWSQLNSGRDVSEIPSALIGTKAPTLDMPRLEGAVAPSGRPMPALTDTAV
KGKLTLVNVWASWCVPCRQEHPVILALSKDPRLTVVGINYKDRNENALRFLGELGNPFSAIGVDPNGKAAIDWGVYGIPE
SFLVAADGTILYKRAGPFDEKSLREGLLPAIEKALAGS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=181, Percent_Identity=39.7790055248619, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21317; Mature: 21186

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNARDERAPGAIRYLVAALPLLIFAVLALIFWSQLNSGRDVSEIPSALIGTKAPTLDMP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
RLEGAVAPSGRPMPALTDTAVKGKLTLVNVWASWCVPCRQEHPVILALSKDPRLTVVGIN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCEEEEECC
YKDRNENALRFLGELGNPFSAIGVDPNGKAAIDWGVYGIPESFLVAADGTILYKRAGPFD
CCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCEECCCCCEEEECCCEEEEECCCCCC
EKSLREGLLPAIEKALAGS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNARDERAPGAIRYLVAALPLLIFAVLALIFWSQLNSGRDVSEIPSALIGTKAPTLDMP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
RLEGAVAPSGRPMPALTDTAVKGKLTLVNVWASWCVPCRQEHPVILALSKDPRLTVVGIN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCEEEEECC
YKDRNENALRFLGELGNPFSAIGVDPNGKAAIDWGVYGIPESFLVAADGTILYKRAGPFD
CCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCEECCCCCEEEECCCEEEEECCCCCC
EKSLREGLLPAIEKALAGS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8021193 [H]