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The map label for this gene is cycZ [H]

Identifier: 150398280

GI number: 150398280

Start: 3234027

End: 3234797

Strand: Direct

Name: cycZ [H]

Synonym: Smed_3086

Alternate gene names: 150398280

Gene position: 3234027-3234797 (Clockwise)

Preceding gene: 150398279

Following gene: 150398281

Centisome position: 85.51

GC content: 64.07

Gene sequence:

>771_bases
ATGAGCGAAAACAGCCTGGCCATACGCAAGTTCAGCGATCTCGCCAACCCGACCCGGTTCCTGGCGCTGGCGGCGCGTGC
CCTGCCGTGGCTTGCCGCTCTTACCGCTCTTTTCTTTGCCGCCGGGCTCTGGCTCTCCTTCACCACCGAGGGCGACTATC
AGCAGGGAGAGACCGTGCGCATCATGTATGTGCATGTGCCTTCGGCCTGGCTGTCCATGATGTGCTATACGGTCATGGCG
ATCTCGGCGCTCGGCACCCTCGTCTGGCGCCATCCGCTCGCAGACGTCTCGGCAAAGGCCGCAGCGCCGATCGGCGCCTG
CTTCACCTTTCTGGCGCTCGTCACCGGCTCGCTCTGGGGAAAGCCGATGTGGGGCACCTGGTGGGTATGGGATGCGCGGC
TGACCTCGGTCTTCGTGCTCTTCCTCATGTATCTCGGCCTGATCGCGCTGAATCGCGCCATGGATGATCCGAGCCGTTCG
GCGCGCGTCTCGGCCGTGCTCGTTCTCGTCGGTTTCGTCAACATCCCGATCATCAAGTTCTCGGTCGATTGGTGGAACAC
GCTGCATCAGCCGGCGAGCGTCATACGCCTGGACGGTCCGACGATCGATCCGGAATTCCTGCGGCCGCTCATCGTCATGG
CAATTGCCTTCACGCTGCTGTTCTTCACGCTGCACATCGGCGCGATGCGCAACGAGATCTGGCGCCGCCGGGTGGCCTCG
CTCAGGCGGCAGGCGGCTCGAAACGCGGGCCGGGAGCAGCTTGCACCATGA

Upstream 100 bases:

>100_bases
GACCCGTGGCGGCCGCCTCAGCCCTCAGGCATTCGGCCGACTGAGACACGGCACTTTAGGATCGATTGCGGAAGGGGTGC
TTCCGCGTTAAAGAGCCAAT

Downstream 100 bases:

>100_bases
TGAGCCATGCGACCTATGTCATTGCCTGCTACGCGGTCTCCGCCGCGACGGTGGCGGGGCTCATCTTCTGGGTCCTAACC
GATGGCCGTGCCCGTAAGCG

Product: heme exporter protein CcmC

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSENSLAIRKFSDLANPTRFLALAARALPWLAALTALFFAAGLWLSFTTEGDYQQGETVRIMYVHVPSAWLSMMCYTVMA
ISALGTLVWRHPLADVSAKAAAPIGACFTFLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRS
ARVSAVLVLVGFVNIPIIKFSVDWWNTLHQPASVIRLDGPTIDPEFLRPLIVMAIAFTLLFFTLHIGAMRNEIWRRRVAS
LRRQAARNAGREQLAP

Sequences:

>Translated_256_residues
MSENSLAIRKFSDLANPTRFLALAARALPWLAALTALFFAAGLWLSFTTEGDYQQGETVRIMYVHVPSAWLSMMCYTVMA
ISALGTLVWRHPLADVSAKAAAPIGACFTFLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRS
ARVSAVLVLVGFVNIPIIKFSVDWWNTLHQPASVIRLDGPTIDPEFLRPLIVMAIAFTLLFFTLHIGAMRNEIWRRRVAS
LRRQAARNAGREQLAP
>Mature_255_residues
SENSLAIRKFSDLANPTRFLALAARALPWLAALTALFFAAGLWLSFTTEGDYQQGETVRIMYVHVPSAWLSMMCYTVMAI
SALGTLVWRHPLADVSAKAAAPIGACFTFLALVTGSLWGKPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRSA
RVSAVLVLVGFVNIPIIKFSVDWWNTLHQPASVIRLDGPTIDPEFLRPLIVMAIAFTLLFFTLHIGAMRNEIWRRRVASL
RRQAARNAGREQLAP

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=226, Percent_Identity=47.787610619469, Blast_Score=200, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28627; Mature: 28496

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSLAIRKFSDLANPTRFLALAARALPWLAALTALFFAAGLWLSFTTEGDYQQGETVR
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEE
IMYVHVPSAWLSMMCYTVMAISALGTLVWRHPLADVSAKAAAPIGACFTFLALVTGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRSARVSAVLVLVGFVNIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEE
SVDWWNTLHQPASVIRLDGPTIDPEFLRPLIVMAIAFTLLFFTLHIGAMRNEIWRRRVAS
EHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRQAARNAGREQLAP
HHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SENSLAIRKFSDLANPTRFLALAARALPWLAALTALFFAAGLWLSFTTEGDYQQGETVR
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEE
IMYVHVPSAWLSMMCYTVMAISALGTLVWRHPLADVSAKAAAPIGACFTFLALVTGSLWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC
KPMWGTWWVWDARLTSVFVLFLMYLGLIALNRAMDDPSRSARVSAVLVLVGFVNIPIIKF
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEE
SVDWWNTLHQPASVIRLDGPTIDPEFLRPLIVMAIAFTLLFFTLHIGAMRNEIWRRRVAS
EHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRQAARNAGREQLAP
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]