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The map label for this gene is soxB [H]

Identifier: 150398023

GI number: 150398023

Start: 2948831

End: 2950162

Strand: Direct

Name: soxB [H]

Synonym: Smed_2825

Alternate gene names: 150398023

Gene position: 2948831-2950162 (Clockwise)

Preceding gene: 150398021

Following gene: 150398024

Centisome position: 77.97

GC content: 66.82

Gene sequence:

>1332_bases
ATGCCCGGCCCCGCTCTCGACCCTGTTGGAACAGATCCTTCGCTTCCCGCGAGAGCCGACGTCGTGATCATCGGCGGCGG
CATCATCGGAGTAACCACCGCGCTTTTTCTTGCAGAGCGAGGCGTGACAGTCGTCCTTTGCGAAAAGGGCGTGCTGGCCG
GCGAGCAATCGAGCCGCAACTGGGGCTGGGTGCGGGTCATGGGCCGCGATCGGCGTGAAATTCCGCTCGCGATGGCGGCG
CTGAACATCTGGGATACGCTCGACGCGCGCGTCTGCGGCGAAACCGGGTTCCGCCGCAGCGGCATCCTCTACATTTCCGA
GACGGAGCAGGACGTCGCAAATCGGGACGCCTGGCTCGCGCTTGCGCGGCCGCATGGCGTCGACAGTCGCCAGCTTACCG
CCGACGAGACCCGGGAACGAATGGGCGGGGCGGCGATACGATACAAGGGCTCGCTCTATACGCCGGGCGACGGCAGGGCC
GAGCCGCAAAAGGCCGTTCCCGCCATCGCCGCCGGAGCGCGTCGCGCCGGCGCGCGCATCGTGACCGGCTGTGCCGTGCG
GGGAATCGAGAAGAGCACGGGCCGAATAAGCGCCGTCATCACCGAAAAGGGCCGCATCGAAACATCTACCGTGGTGCTTG
CCGGCGGCGCTTGGTCCAGGCTCTTCTGCAAGGGGCTCGGAGTCCGGCTGCCGCAATTGAAAGTGCGTAACACCGTGCTC
CGGACGGCACCGGTCGAGGGCGGGCCGGATGGTGCCGGTGCGACGGCGACCTACGCCTATCGCAAGCGCCTCGACGGCGG
CTATACGATCGCCACCGCAGGCGCAAACCTGCACCCGCTCGTGCCCGACACCTTTGCGTTTTTTCAGGATTTTCGGGAGG
CTCGGAAGGCCGAAGGCGAGTCCGTGCAGGCGGGCCTGAGCGCCCAGAGCTGGCGTGAGCTCTTCGAGATCCTGCCGCAA
CCGCTCGATCGGCCAGGCGCCTTCGAGCGGCACCGCATCCTCGACCCGCGTCCCGATCCTAAGTCCGTGCTCAGGGCTTT
CGAAGAGGCAAGAAAGGCTCTTCCGAAGCTTCGGACCGTCGCGCCGGTGCAGATCTGGGCCGGACTGATCGACGTGACAC
CGGACGTCGTGCCGGTCATTTCCCTGGCGCAAGAGCTGCCGGGGCTCGTTATCGCTACCGGCTTTTCCGGTCACGGCTTC
GGCATCGGCCCCGGGGCCGGACATCTCGTCGCCGATCTCGTGACCGGAGACCCGCCCATCGTCGATCCCTCCGAGTTCCG
CCTTTCGCGCTTTTCCGACGGCAGCCCGATTGAGATCGCTCCGCCGGTCTGA

Upstream 100 bases:

>100_bases
GGAACTGTGCATCGCTGCCGGAAACCGGCTCTGAAGGCTTGATCGGTGCGTTCATTGGATGCAGCGATAGGGAATAAATG
CACGGAACCCAGAGATCATC

Downstream 100 bases:

>100_bases
GGGTGGGTCAAGCACTTGCTGCGTGTTCGCGGCAGCCTCACGAAAGAAAATTGCCCGCCATCAGCATCGGCATGATCACG
CCGACGCATGCCGGATGCGT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPGPALDPVGTDPSLPARADVVIIGGGIIGVTTALFLAERGVTVVLCEKGVLAGEQSSRNWGWVRVMGRDRREIPLAMAA
LNIWDTLDARVCGETGFRRSGILYISETEQDVANRDAWLALARPHGVDSRQLTADETRERMGGAAIRYKGSLYTPGDGRA
EPQKAVPAIAAGARRAGARIVTGCAVRGIEKSTGRISAVITEKGRIETSTVVLAGGAWSRLFCKGLGVRLPQLKVRNTVL
RTAPVEGGPDGAGATATYAYRKRLDGGYTIATAGANLHPLVPDTFAFFQDFREARKAEGESVQAGLSAQSWRELFEILPQ
PLDRPGAFERHRILDPRPDPKSVLRAFEEARKALPKLRTVAPVQIWAGLIDVTPDVVPVISLAQELPGLVIATGFSGHGF
GIGPGAGHLVADLVTGDPPIVDPSEFRLSRFSDGSPIEIAPPV

Sequences:

>Translated_443_residues
MPGPALDPVGTDPSLPARADVVIIGGGIIGVTTALFLAERGVTVVLCEKGVLAGEQSSRNWGWVRVMGRDRREIPLAMAA
LNIWDTLDARVCGETGFRRSGILYISETEQDVANRDAWLALARPHGVDSRQLTADETRERMGGAAIRYKGSLYTPGDGRA
EPQKAVPAIAAGARRAGARIVTGCAVRGIEKSTGRISAVITEKGRIETSTVVLAGGAWSRLFCKGLGVRLPQLKVRNTVL
RTAPVEGGPDGAGATATYAYRKRLDGGYTIATAGANLHPLVPDTFAFFQDFREARKAEGESVQAGLSAQSWRELFEILPQ
PLDRPGAFERHRILDPRPDPKSVLRAFEEARKALPKLRTVAPVQIWAGLIDVTPDVVPVISLAQELPGLVIATGFSGHGF
GIGPGAGHLVADLVTGDPPIVDPSEFRLSRFSDGSPIEIAPPV
>Mature_442_residues
PGPALDPVGTDPSLPARADVVIIGGGIIGVTTALFLAERGVTVVLCEKGVLAGEQSSRNWGWVRVMGRDRREIPLAMAAL
NIWDTLDARVCGETGFRRSGILYISETEQDVANRDAWLALARPHGVDSRQLTADETRERMGGAAIRYKGSLYTPGDGRAE
PQKAVPAIAAGARRAGARIVTGCAVRGIEKSTGRISAVITEKGRIETSTVVLAGGAWSRLFCKGLGVRLPQLKVRNTVLR
TAPVEGGPDGAGATATYAYRKRLDGGYTIATAGANLHPLVPDTFAFFQDFREARKAEGESVQAGLSAQSWRELFEILPQP
LDRPGAFERHRILDPRPDPKSVLRAFEEARKALPKLRTVAPVQIWAGLIDVTPDVVPVISLAQELPGLVIATGFSGHGFG
IGPGAGHLVADLVTGDPPIVDPSEFRLSRFSDGSPIEIAPPV

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=433, Percent_Identity=25.1732101616628, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI21361378, Length=433, Percent_Identity=25.1732101616628, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI24797151, Length=426, Percent_Identity=22.7699530516432, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI194306651, Length=424, Percent_Identity=22.1698113207547, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130091, Length=432, Percent_Identity=24.0740740740741, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28571104, Length=436, Percent_Identity=24.7706422018349, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 47145; Mature: 47014

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPALDPVGTDPSLPARADVVIIGGGIIGVTTALFLAERGVTVVLCEKGVLAGEQSSRN
CCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC
WGWVRVMGRDRREIPLAMAALNIWDTLDARVCGETGFRRSGILYISETEQDVANRDAWLA
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCEEEE
LARPHGVDSRQLTADETRERMGGAAIRYKGSLYTPGDGRAEPQKAVPAIAAGARRAGARI
EECCCCCCCCCCCHHHHHHHHCCEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHCCCEE
VTGCAVRGIEKSTGRISAVITEKGRIETSTVVLAGGAWSRLFCKGLGVRLPQLKVRNTVL
EEHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHH
RTAPVEGGPDGAGATATYAYRKRLDGGYTIATAGANLHPLVPDTFAFFQDFREARKAEGE
EECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
SVQAGLSAQSWRELFEILPQPLDRPGAFERHRILDPRPDPKSVLRAFEEARKALPKLRTV
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
APVQIWAGLIDVTPDVVPVISLAQELPGLVIATGFSGHGFGIGPGAGHLVADLVTGDPPI
CHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
VDPSEFRLSRFSDGSPIEIAPPV
CCCHHHHHHHCCCCCCEEECCCC
>Mature Secondary Structure 
PGPALDPVGTDPSLPARADVVIIGGGIIGVTTALFLAERGVTVVLCEKGVLAGEQSSRN
CCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCC
WGWVRVMGRDRREIPLAMAALNIWDTLDARVCGETGFRRSGILYISETEQDVANRDAWLA
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHCCCEEEE
LARPHGVDSRQLTADETRERMGGAAIRYKGSLYTPGDGRAEPQKAVPAIAAGARRAGARI
EECCCCCCCCCCCHHHHHHHHCCEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHCCCEE
VTGCAVRGIEKSTGRISAVITEKGRIETSTVVLAGGAWSRLFCKGLGVRLPQLKVRNTVL
EEHHHHCCCCCCCCEEEEEEECCCCEEEEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHH
RTAPVEGGPDGAGATATYAYRKRLDGGYTIATAGANLHPLVPDTFAFFQDFREARKAEGE
EECCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
SVQAGLSAQSWRELFEILPQPLDRPGAFERHRILDPRPDPKSVLRAFEEARKALPKLRTV
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
APVQIWAGLIDVTPDVVPVISLAQELPGLVIATGFSGHGFGIGPGAGHLVADLVTGDPPI
CHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCC
VDPSEFRLSRFSDGSPIEIAPPV
CCCHHHHHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]