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The map label for this gene is cobK [H]

Identifier: 150398012

GI number: 150398012

Start: 2939412

End: 2940212

Strand: Direct

Name: cobK [H]

Synonym: Smed_2814

Alternate gene names: 150398012

Gene position: 2939412-2940212 (Clockwise)

Preceding gene: 150398009

Following gene: 150398019

Centisome position: 77.72

GC content: 67.67

Gene sequence:

>801_bases
ATGGTGGAACCGTTGTTCGACATGTCAGCCACGGGCAAGCCTCGCATTCTGATCCTCGGCGGAACGACCGAGGCGCGGCA
GCTCGCGGAGCACCTTGCCTCCGATCCGCGCTACGACGCTGCGGTCTCCCTTGCCGGCCGCACGGCCGAACCCCGCCCGC
AGCCGCTTCCGACACGCATAGGCGGCTTCGGGGGGGCGGAGGGACTCGCCGCATTCCTGCTGGACGAGGGCATCGCCCTC
CTCGTAGACGCGACGCACCCCTTCGCTGCGCGGATCTCGCAAAACGCCGCCGCTGCGGCTCGAATAACGGGTACGCCAAT
CCTCGCGCTCCGCCGCCCCGCCTGGGAGGCCGGCCCCGGTGATCGCTGGACTCGCGTCGACAGTGTCTCCGAGGCGGTCT
CCGCCCTTGGAGAGGCGCCGCGCCGTGTCTTCCTCGCGATCGGCCGGCAAGAGGCCTTCCATTTCAAGAAAGCGCCGCAG
CACAGCTACGTCATACGCAGCGTCGACCCGATAACGCCGCCGCTCGACCTGCCCGATGCTACCGCCATTCTCGCCTCCGG
CCCTTTTGCCGAGCGGGATGAAACGGAACTGCTCGAACGCAACCGGATCGACGCCATCATTGCCAAGAACAGCGGCGGCG
CGGCCACCTTTGGCAAGATAGCGGCGGCGCGAAAGCTCGGGATCGAGGTGGTGATGGTCGAGCGCCGAAAGCCTGCCGAC
GTTCCGTCGGTCGGCGACTGTAGCGAGGCGCTCGAACGCATCCGTCAACGCTTTGCTCCGGTAAAGGACCGCGGCGTGTA
G

Upstream 100 bases:

>100_bases
GAAGACGACGGGTGCCGCCTGGATGAGGCGCTTGGCCTCTTCGCCGAGACCGGCTACACCGTCCTCTCCGATGCCGATTA
TGATGAGCCAGGGAGCGACG

Downstream 100 bases:

>100_bases
ACGAGATCATGCTTCCCGTCGCGCAGGATGGTACGTGTCTCCGGCGAGCCGATGATCACGCAGGTCGCCATGTCAGCGCG
ACCCGGCTCGGCCTCGCCGA

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MVEPLFDMSATGKPRILILGGTTEARQLAEHLASDPRYDAAVSLAGRTAEPRPQPLPTRIGGFGGAEGLAAFLLDEGIAL
LVDATHPFAARISQNAAAAARITGTPILALRRPAWEAGPGDRWTRVDSVSEAVSALGEAPRRVFLAIGRQEAFHFKKAPQ
HSYVIRSVDPITPPLDLPDATAILASGPFAERDETELLERNRIDAIIAKNSGGAATFGKIAAARKLGIEVVMVERRKPAD
VPSVGDCSEALERIRQRFAPVKDRGV

Sequences:

>Translated_266_residues
MVEPLFDMSATGKPRILILGGTTEARQLAEHLASDPRYDAAVSLAGRTAEPRPQPLPTRIGGFGGAEGLAAFLLDEGIAL
LVDATHPFAARISQNAAAAARITGTPILALRRPAWEAGPGDRWTRVDSVSEAVSALGEAPRRVFLAIGRQEAFHFKKAPQ
HSYVIRSVDPITPPLDLPDATAILASGPFAERDETELLERNRIDAIIAKNSGGAATFGKIAAARKLGIEVVMVERRKPAD
VPSVGDCSEALERIRQRFAPVKDRGV
>Mature_266_residues
MVEPLFDMSATGKPRILILGGTTEARQLAEHLASDPRYDAAVSLAGRTAEPRPQPLPTRIGGFGGAEGLAAFLLDEGIAL
LVDATHPFAARISQNAAAAARITGTPILALRRPAWEAGPGDRWTRVDSVSEAVSALGEAPRRVFLAIGRQEAFHFKKAPQ
HSYVIRSVDPITPPLDLPDATAILASGPFAERDETELLERNRIDAIIAKNSGGAATFGKIAAARKLGIEVVMVERRKPAD
VPSVGDCSEALERIRQRFAPVKDRGV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 28392; Mature: 28392

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPLFDMSATGKPRILILGGTTEARQLAEHLASDPRYDAAVSLAGRTAEPRPQPLPTRI
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHH
GGFGGAEGLAAFLLDEGIALLVDATHPFAARISQNAAAAARITGTPILALRRPAWEAGPG
CCCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHEEEECCCEEEEEECCCCCCCCC
DRWTRVDSVSEAVSALGEAPRRVFLAIGRQEAFHFKKAPQHSYVIRSVDPITPPLDLPDA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
TAILASGPFAERDETELLERNRIDAIIAKNSGGAATFGKIAAARKLGIEVVMVERRKPAD
CEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
VPSVGDCSEALERIRQRFAPVKDRGV
CCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVEPLFDMSATGKPRILILGGTTEARQLAEHLASDPRYDAAVSLAGRTAEPRPQPLPTRI
CCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHH
GGFGGAEGLAAFLLDEGIALLVDATHPFAARISQNAAAAARITGTPILALRRPAWEAGPG
CCCCCHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCHHEEEECCCEEEEEECCCCCCCCC
DRWTRVDSVSEAVSALGEAPRRVFLAIGRQEAFHFKKAPQHSYVIRSVDPITPPLDLPDA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
TAILASGPFAERDETELLERNRIDAIIAKNSGGAATFGKIAAARKLGIEVVMVERRKPAD
CEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
VPSVGDCSEALERIRQRFAPVKDRGV
CCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]