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The map label for this gene is lig [H]

Identifier: 150398001

GI number: 150398001

Start: 2925710

End: 2926726

Strand: Direct

Name: lig [H]

Synonym: Smed_2803

Alternate gene names: 150398001

Gene position: 2925710-2926726 (Clockwise)

Preceding gene: 150398000

Following gene: 150398002

Centisome position: 77.36

GC content: 63.91

Gene sequence:

>1017_bases
ATGCCTATGAAGCCGGACGCCTTGCTCTACCCCGCCCCGAAAGGTCTCTACTGCGAACGCGGAGACTTCTACATCGACCC
GGTGCAGCCGGTCGAACGGGCACTTATCACCCACGGACATTCCGACCATGCTCGCGCCGGGCATGGCCATGTACTTGCGA
CACGCGAGACACTCGACATCATGCGCCTGCGCTATGGCGAGGAGTTCTGCGGCGGGAGCCAAATCGCGCGCTTTGGCGAA
ACGATTGCGATCGGTGACGTGCGCGTCCGGTTTCACCCGGCCGGCCATGTGCTCGGATCGGCACAGATAGCGGTCGAGGC
AAACGGTACACGCATCGTCGTTTCCGGCGATTACAAGCGACGGCCCGATCCGACCTGCCCGCCCTTCGAGCCGGTCGCCT
GCGACGTCTTCATCACTGAAGCGACATTCGGCCTGCCTGTCTTCCACCACCCCGACGACAAGGGAGAGGTCGCCCGGTTG
CTCCTGTCCCTCAGACAGTTCCCCGAGCGCGCGCATGTGGTCGGCGCCTATGCGCTTGGGAAGGCACAACGCCTCATCGC
ACTCATACGCCAGCAGGGCTATACCGAACCGATCCACATCCACGGCGCACTCGCCAAACTCTGCGAATATTATCAGAGCC
AGGGCATCGAGCTTGGCGACATCCGTCCGGCGACGCTCGGCCCGGAAAATCGCCAGGATCTCGCAGGCAGCATCGTTGTC
GGACCACCGGCAGCTTTCGCCGAGCGCTGGTCGCGCCGCTTCGCCGATCCGCTCGCCATCTTCGCGTCCGGCTGGATGCT
CATCCGCCAGCGTGCCAAGCAGCGTGGCGTCGAACTGCCGCTCGTCATCTCCGACCATTGCGATTGGGCGGAACTCACCG
CCACGATCAAGGAAATCGCCCCTTCGGAGCTCTGGGTGACACATGGACGCGAGGAAGCGCTGGTTCGCTGGTGCCAGTTG
CAGGGAATCCCGGCACGCCCGCTGCACCTTGTCGGCTACGATGACGAGGGGGAGTGA

Upstream 100 bases:

>100_bases
CCGCTCCCTTACCCGATGGCCAAATCGCCACGGCGCAGCCCCCCTTGCGGCGAAAATCTTTCGCAAATGGCTGGCAGACG
CGCTGCCGCCGGCTATCTTT

Downstream 100 bases:

>100_bases
GCGATGAAAGCCTTCGCCGAATTGCTCGACCGGCTGGTGCTGACGCCGCAGCGAAACGCCAAGATCCGGCTGCTCGTCGA
TTACTTCCACAGCGCGCCCG

Product: putative mRNA 3-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPMKPDALLYPAPKGLYCERGDFYIDPVQPVERALITHGHSDHARAGHGHVLATRETLDIMRLRYGEEFCGGSQIARFGE
TIAIGDVRVRFHPAGHVLGSAQIAVEANGTRIVVSGDYKRRPDPTCPPFEPVACDVFITEATFGLPVFHHPDDKGEVARL
LLSLRQFPERAHVVGAYALGKAQRLIALIRQQGYTEPIHIHGALAKLCEYYQSQGIELGDIRPATLGPENRQDLAGSIVV
GPPAAFAERWSRRFADPLAIFASGWMLIRQRAKQRGVELPLVISDHCDWAELTATIKEIAPSELWVTHGREEALVRWCQL
QGIPARPLHLVGYDDEGE

Sequences:

>Translated_338_residues
MPMKPDALLYPAPKGLYCERGDFYIDPVQPVERALITHGHSDHARAGHGHVLATRETLDIMRLRYGEEFCGGSQIARFGE
TIAIGDVRVRFHPAGHVLGSAQIAVEANGTRIVVSGDYKRRPDPTCPPFEPVACDVFITEATFGLPVFHHPDDKGEVARL
LLSLRQFPERAHVVGAYALGKAQRLIALIRQQGYTEPIHIHGALAKLCEYYQSQGIELGDIRPATLGPENRQDLAGSIVV
GPPAAFAERWSRRFADPLAIFASGWMLIRQRAKQRGVELPLVISDHCDWAELTATIKEIAPSELWVTHGREEALVRWCQL
QGIPARPLHLVGYDDEGE
>Mature_337_residues
PMKPDALLYPAPKGLYCERGDFYIDPVQPVERALITHGHSDHARAGHGHVLATRETLDIMRLRYGEEFCGGSQIARFGET
IAIGDVRVRFHPAGHVLGSAQIAVEANGTRIVVSGDYKRRPDPTCPPFEPVACDVFITEATFGLPVFHHPDDKGEVARLL
LSLRQFPERAHVVGAYALGKAQRLIALIRQQGYTEPIHIHGALAKLCEYYQSQGIELGDIRPATLGPENRQDLAGSIVVG
PPAAFAERWSRRFADPLAIFASGWMLIRQRAKQRGVELPLVISDHCDWAELTATIKEIAPSELWVTHGREEALVRWCQLQ
GIPARPLHLVGYDDEGE

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37448; Mature: 37317

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00436 PEROXIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKPDALLYPAPKGLYCERGDFYIDPVQPVERALITHGHSDHARAGHGHVLATRETLDI
CCCCCCCEEECCCCCCEECCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHH
MRLRYGEEFCGGSQIARFGETIAIGDVRVRFHPAGHVLGSAQIAVEANGTRIVVSGDYKR
HHHHHCHHHCCCHHHHHCCCEEEEEEEEEEEECCCCEECCEEEEEEECCCEEEEECCCCC
RPDPTCPPFEPVACDVFITEATFGLPVFHHPDDKGEVARLLLSLRQFPERAHVVGAYALG
CCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCHHHEEEHHHHH
KAQRLIALIRQQGYTEPIHIHGALAKLCEYYQSQGIELGDIRPATLGPENRQDLAGSIVV
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHCCEEEE
GPPAAFAERWSRRFADPLAIFASGWMLIRQRAKQRGVELPLVISDHCDWAELTATIKEIA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC
PSELWVTHGREEALVRWCQLQGIPARPLHLVGYDDEGE
CCCEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PMKPDALLYPAPKGLYCERGDFYIDPVQPVERALITHGHSDHARAGHGHVLATRETLDI
CCCCCCEEECCCCCCEECCCCEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHH
MRLRYGEEFCGGSQIARFGETIAIGDVRVRFHPAGHVLGSAQIAVEANGTRIVVSGDYKR
HHHHHCHHHCCCHHHHHCCCEEEEEEEEEEEECCCCEECCEEEEEEECCCEEEEECCCCC
RPDPTCPPFEPVACDVFITEATFGLPVFHHPDDKGEVARLLLSLRQFPERAHVVGAYALG
CCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHCCCHHHEEEHHHHH
KAQRLIALIRQQGYTEPIHIHGALAKLCEYYQSQGIELGDIRPATLGPENRQDLAGSIVV
HHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHCCEEEE
GPPAAFAERWSRRFADPLAIFASGWMLIRQRAKQRGVELPLVISDHCDWAELTATIKEIA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHC
PSELWVTHGREEALVRWCQLQGIPARPLHLVGYDDEGE
CCCEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA