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The map label for this gene is yajO [H]

Identifier: 150397933

GI number: 150397933

Start: 2845880

End: 2846914

Strand: Direct

Name: yajO [H]

Synonym: Smed_2735

Alternate gene names: 150397933

Gene position: 2845880-2846914 (Clockwise)

Preceding gene: 150397931

Following gene: 150397934

Centisome position: 75.25

GC content: 63.29

Gene sequence:

>1035_bases
ATGGAATATAGACGGCTTGGTTCCTCCGGACTGAAAGTACCGGCCCTCAGCTTTGGTGCGGGCACATTCGGAGGCAAGGG
GCCACTCTTTAGCGCCTGGGGCAGTACGGACACGGAAGAAGCCCGGCGCCTCATCGACATCTGTCTCGAGGCGGGCGTCA
ATCTTTTCGACACGGCGGATGTCTATTCCGACGGCGCTTCGGAGGATGTCCTCGGAGCGGCGATCCGGGGACGGCGCGAC
GACGTGATCCTGTCGACGAAACTGACGCTCCCCACGGGAGATGGGCCTAACGACGCCGGCTCGTCGCGCTCGCGCTTGAT
CCGCGGTGTGGATCACGCGCTGAAGCGGCTCGGAACCGACTATATCGACCTGCTTCAGCTCCACGCCTTTGATGCGGGGA
CGCCCGTCGAAGAAGTGCTGTCTACCCTCGACACGCTCGTGCGCTCCGGCAAACTGCGCTATGTCGGTGTTTCCAACTTT
TCCGGTTGGCAGCTGATGAAATCGCTCGCTGTCGCCGATCGGCATGGCTATCCTCGCTACGTCGCCAACCAGGTCTACTA
TTCGCTGGCCGGCCGCGACTATGAATGGGAACTGATGCCGCTCGGTCTCGATCAGGGCGTCGGCGCGCTCGTCTGGAGCC
CGCTCGGTTGGGGGCGGCTCACCGGTAAGATCCGCCGTGGCGAGCCCTGGCCGCAGGGCAGCCGCCTGCACGAAACCGCC
GCCTTCGGGCCGCCCGTCGATGAGGAAAAGCTATACGATATCGTTGACGTTCTCGATGCTATCGCGCAGGAAACCGGCAA
AACGGTCCCGCAAATCGCCATCAACTGGCTCCTCCGGCGTCCATCCGTTTCGAGCGTCATCATCGGCGCGCGCAATGAAG
AGCAGCTTCGGCAGAACCTCGGAGCGGTCGGCTGGTCGCTCTCGGCCGATGAGGTAGCCCGCCTCGACGCCGCGAGTGCG
ACGACTGCTCCCTACCCCTACTTCCCCTATTTCAGGCAGGAAGGCTTTGCCCGGATCAATCCTCCGGCCGTCTGA

Upstream 100 bases:

>100_bases
ATTCAGCTCACAGATAATATTCCTTTTAGCAGCCTATATCCAAAGTGCCAGAGGCTCCATCTTCGTGTAACCAGTTCATT
GTCAAGAATGGAGTTGCGAA

Downstream 100 bases:

>100_bases
CCGGCGGGAGATCGCCTTGGAACGCGGCCGGAACCGTCCAACGGTTTCGGCCGGCGCGGCCGCCAAGGAGCCACGCGGCA
TGGCGGGCACACCAGGTGAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MEYRRLGSSGLKVPALSFGAGTFGGKGPLFSAWGSTDTEEARRLIDICLEAGVNLFDTADVYSDGASEDVLGAAIRGRRD
DVILSTKLTLPTGDGPNDAGSSRSRLIRGVDHALKRLGTDYIDLLQLHAFDAGTPVEEVLSTLDTLVRSGKLRYVGVSNF
SGWQLMKSLAVADRHGYPRYVANQVYYSLAGRDYEWELMPLGLDQGVGALVWSPLGWGRLTGKIRRGEPWPQGSRLHETA
AFGPPVDEEKLYDIVDVLDAIAQETGKTVPQIAINWLLRRPSVSSVIIGARNEEQLRQNLGAVGWSLSADEVARLDAASA
TTAPYPYFPYFRQEGFARINPPAV

Sequences:

>Translated_344_residues
MEYRRLGSSGLKVPALSFGAGTFGGKGPLFSAWGSTDTEEARRLIDICLEAGVNLFDTADVYSDGASEDVLGAAIRGRRD
DVILSTKLTLPTGDGPNDAGSSRSRLIRGVDHALKRLGTDYIDLLQLHAFDAGTPVEEVLSTLDTLVRSGKLRYVGVSNF
SGWQLMKSLAVADRHGYPRYVANQVYYSLAGRDYEWELMPLGLDQGVGALVWSPLGWGRLTGKIRRGEPWPQGSRLHETA
AFGPPVDEEKLYDIVDVLDAIAQETGKTVPQIAINWLLRRPSVSSVIIGARNEEQLRQNLGAVGWSLSADEVARLDAASA
TTAPYPYFPYFRQEGFARINPPAV
>Mature_344_residues
MEYRRLGSSGLKVPALSFGAGTFGGKGPLFSAWGSTDTEEARRLIDICLEAGVNLFDTADVYSDGASEDVLGAAIRGRRD
DVILSTKLTLPTGDGPNDAGSSRSRLIRGVDHALKRLGTDYIDLLQLHAFDAGTPVEEVLSTLDTLVRSGKLRYVGVSNF
SGWQLMKSLAVADRHGYPRYVANQVYYSLAGRDYEWELMPLGLDQGVGALVWSPLGWGRLTGKIRRGEPWPQGSRLHETA
AFGPPVDEEKLYDIVDVLDAIAQETGKTVPQIAINWLLRRPSVSSVIIGARNEEQLRQNLGAVGWSLSADEVARLDAASA
TTAPYPYFPYFRQEGFARINPPAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=36.0128617363344, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=36.0128617363344, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=35.6913183279743, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI27436969, Length=319, Percent_Identity=35.1097178683386, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI4504825, Length=317, Percent_Identity=35.0157728706625, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=31.4102564102564, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223718702, Length=274, Percent_Identity=28.8321167883212, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=28.8321167883212, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41152114, Length=269, Percent_Identity=28.6245353159851, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718708, Length=145, Percent_Identity=32.4137931034483, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=37.3134328358209, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=31.0924369747899, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788070, Length=337, Percent_Identity=30.5637982195846, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788081, Length=276, Percent_Identity=29.3478260869565, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994888, Length=320, Percent_Identity=26.5625, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=327, Percent_Identity=22.6299694189602, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17550248, Length=327, Percent_Identity=22.9357798165138, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=332, Percent_Identity=27.710843373494, Blast_Score=160, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=29.7872340425532, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=29.5918367346939, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319951, Length=325, Percent_Identity=27.0769230769231, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=27.5862068965517, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=157, Percent_Identity=32.484076433121, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=29.7297297297297, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24640980, Length=325, Percent_Identity=26.4615384615385, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45549126, Length=325, Percent_Identity=26.4615384615385, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646159, Length=316, Percent_Identity=27.5316455696203, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644950, Length=338, Percent_Identity=24.8520710059172, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37471; Mature: 37471

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRLGSSGLKVPALSFGAGTFGGKGPLFSAWGSTDTEEARRLIDICLEAGVNLFDTAD
CCCHHCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHH
VYSDGASEDVLGAAIRGRRDDVILSTKLTLPTGDGPNDAGSSRSRLIRGVDHALKRLGTD
HHCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
YIDLLQLHAFDAGTPVEEVLSTLDTLVRSGKLRYVGVSNFSGWQLMKSLAVADRHGYPRY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHH
VANQVYYSLAGRDYEWELMPLGLDQGVGALVWSPLGWGRLTGKIRRGEPWPQGSRLHETA
HHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHCCEEECCCCCCCCCCHHHHH
AFGPPVDEEKLYDIVDVLDAIAQETGKTVPQIAINWLLRRPSVSSVIIGARNEEQLRQNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
GAVGWSLSADEVARLDAASATTAPYPYFPYFRQEGFARINPPAV
HHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEYRRLGSSGLKVPALSFGAGTFGGKGPLFSAWGSTDTEEARRLIDICLEAGVNLFDTAD
CCCHHCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHH
VYSDGASEDVLGAAIRGRRDDVILSTKLTLPTGDGPNDAGSSRSRLIRGVDHALKRLGTD
HHCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCH
YIDLLQLHAFDAGTPVEEVLSTLDTLVRSGKLRYVGVSNFSGWQLMKSLAVADRHGYPRY
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHH
VANQVYYSLAGRDYEWELMPLGLDQGVGALVWSPLGWGRLTGKIRRGEPWPQGSRLHETA
HHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHCCEEECCCCCCCCCCHHHHH
AFGPPVDEEKLYDIVDVLDAIAQETGKTVPQIAINWLLRRPSVSSVIIGARNEEQLRQNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
GAVGWSLSADEVARLDAASATTAPYPYFPYFRQEGFARINPPAV
HHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]