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The map label for this gene is yuxG [H]

Identifier: 150397891

GI number: 150397891

Start: 2798446

End: 2800494

Strand: Reverse

Name: yuxG [H]

Synonym: Smed_2693

Alternate gene names: 150397891

Gene position: 2800494-2798446 (Counterclockwise)

Preceding gene: 150397892

Following gene: 150397890

Centisome position: 74.05

GC content: 62.08

Gene sequence:

>2049_bases
ATGAAATCGCGCTGGTCGGACTCCGAGTTCACCTCCATCATCGATGCCTATGTCGCCAAAGGCGTCAATCGGGACCTCGC
CATTCGCACCTATACGACCCGTCTGCTCGGCTCCGATCCGGAACTGGTATTGCACGGCGGCGGAAACACTTCGGTCAAGA
CCACCTTTACGGAGATGGACGGCAGCGAGGTGGACGTGCTCTGCGTCAAGGGCAGCGGATGGGATATGGGCACGATCGAG
CCGCAGGGCCTGCCGGCCGTCCGCCTGCAGCCGCTGCAGGCCATGATCGATTTCGAGACGCTCTCCGACGACGACATGGT
GATGCTTCAACGCCGCCTGCTTGTCGATCCAGCGGCGCCCAATCCGTCGGTCGAGGCCATTCTGCATGCGATCCTGCCCT
TCAAGCACATCGATCATACCCATGCGAACGCCATCGTCTCGCTCACCAATCAGCCGCACGGCGAGGATCTGATCCGAGAA
CTATTCCCCGATGCGATCATCGTTCCCTATGTGATGCCGGGCTTCGATCTGGCAAAGGCTTGCGACACTGCCTTCAAGGC
TGATCCGAAAGGCGACGGCATGATCCTGCTGAAGCACGGCATCTTCACCTGGTCGGAGGATCCGCGCGAAGCCTACGAGG
ATATGATCGCCAAAATCGACAAGGCCGAGCGGCGCCTGTCCCAAGGCCGGGCGAAGCCGTTCAGGAGCATTGCCGTTCCC
GCAGGCCTGGCCGCTGCCGCGGATATCGCGCCGATTCTGCGTGGTGCGCTGGCGATCGACACCGGTATCGAAGGAGCGCC
GAAACGCTTCGTTCTCGAACATCGTACCAGCGAAAAGATACTCGACTTCTGCAACGCCGAAAATATCGAAAGCCTCGTCC
GCCGCGGCAATGCGACGCCGGAACATGTGATCCATATCAAGCGCTTCGGCGTTGCTCTGCCCGCTCCGGAGAAGAACAGA
CTTGGAGAATGGGCGGTGCGTGCAAGGGAAGCGGTTGCCGCTTATCAGGCCGACTACCAGGCCTATTTCGAACGGAACAA
TGCCCGCGTCGGGGGTGGCAAGCGCATGCTCGATCCGAAGCCGCGCGTCTTCTACGTCGCCGGCATCGGCCTCTTCGCCG
CCGGGGCAGCGCGAAAAAACGCGACGGTCGGCGCCGACGTTGCGGAAGCAACGATAGATGTCATCACGAAGGCGGAAGGC
ATCGAGGCCTTCGAGGCGCTCTCGGAGCGCGATCTTTTCGACATCGAATACTGGTCGCTCGAGCAGGTGAAGCTGACAAA
GGTGCAGGAAAAGCCGCTGACGCGGCAGGTTGCAATCGTCACCGGCGCGGCAAGCGGACTCGGCTTTGCTGTCGCGGAAG
CCTTGAAGGCGGAAGGTGCCGAACTCGCGCTCTTCGACATTTCAGAAGATGCGCTGAACGCGGCGGCGAAAAAACTCGGC
GCGCTGCCGGTGCTCTGCGACGTGACGAGTTCCGAGGCGGTCGACGCGGCGGTCGCCAGGGTCGCGCAGCACTATGGTGG
TGTGGATATTCTGATCTCGAATGCGGGCGCAGCCTTCCAGGGCAAACTGCTCAGCGTCGATGAGGCGACCTTCCGAAAGG
CCTTCGATCTCAATTTCTGGAGCCATCACTACGTCGCGCGCGCGGTGGTACGCGTCATGGAACAGCAGAAGTCAGGCGGC
TCGCTGGTCTTCAACGTCTCCAAGCAAGCCGTGAATCCCGGCGCCGACTTCGGCCCCTATGGAACCTCGAAGGCGGCACT
GATGGCGCTGATGCGGCAATATGCCATTGAGCACGGCGGCTCCGGCATCACGTCGAACGCCGTCAATGCGGACCGGATTC
GCACCGGCCTGATGACCGACAAGATGGTCGAGGAACGCTCGATGGCGCGTGGCCTGACGCCGGAGGATTACATGCGGGGC
AACATGCTTCGCCGCGAGGTGACCGGCGCCGATGTGGCAGCGGCCTTCGTGCATCTCGCCAAGGCCCGGACCTCCACCGG
AGCAGTCGTTACCGTCGACGGCGGCAACGTTGCCGCGATGATGCGTTGA

Upstream 100 bases:

>100_bases
CGAAACAGAGATCCGCATTTGACGCTGCGGACCGGACATCACCCACCCGATCGACTGTATCCGGGCGCTGCAAACGGTGC
CGGCAAGGAAAGGAACTGCC

Downstream 100 bases:

>100_bases
GGGCGCGCGGGAACAGGTAAGCGGAGAAACCGAAAGATGGCAACCATCCTCATTCTCGGGGCGGGCGTGATGGGTACCGC
CCTGGCGGTACCGGCAAGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MKSRWSDSEFTSIIDAYVAKGVNRDLAIRTYTTRLLGSDPELVLHGGGNTSVKTTFTEMDGSEVDVLCVKGSGWDMGTIE
PQGLPAVRLQPLQAMIDFETLSDDDMVMLQRRLLVDPAAPNPSVEAILHAILPFKHIDHTHANAIVSLTNQPHGEDLIRE
LFPDAIIVPYVMPGFDLAKACDTAFKADPKGDGMILLKHGIFTWSEDPREAYEDMIAKIDKAERRLSQGRAKPFRSIAVP
AGLAAAADIAPILRGALAIDTGIEGAPKRFVLEHRTSEKILDFCNAENIESLVRRGNATPEHVIHIKRFGVALPAPEKNR
LGEWAVRAREAVAAYQADYQAYFERNNARVGGGKRMLDPKPRVFYVAGIGLFAAGAARKNATVGADVAEATIDVITKAEG
IEAFEALSERDLFDIEYWSLEQVKLTKVQEKPLTRQVAIVTGAASGLGFAVAEALKAEGAELALFDISEDALNAAAKKLG
ALPVLCDVTSSEAVDAAVARVAQHYGGVDILISNAGAAFQGKLLSVDEATFRKAFDLNFWSHHYVARAVVRVMEQQKSGG
SLVFNVSKQAVNPGADFGPYGTSKAALMALMRQYAIEHGGSGITSNAVNADRIRTGLMTDKMVEERSMARGLTPEDYMRG
NMLRREVTGADVAAAFVHLAKARTSTGAVVTVDGGNVAAMMR

Sequences:

>Translated_682_residues
MKSRWSDSEFTSIIDAYVAKGVNRDLAIRTYTTRLLGSDPELVLHGGGNTSVKTTFTEMDGSEVDVLCVKGSGWDMGTIE
PQGLPAVRLQPLQAMIDFETLSDDDMVMLQRRLLVDPAAPNPSVEAILHAILPFKHIDHTHANAIVSLTNQPHGEDLIRE
LFPDAIIVPYVMPGFDLAKACDTAFKADPKGDGMILLKHGIFTWSEDPREAYEDMIAKIDKAERRLSQGRAKPFRSIAVP
AGLAAAADIAPILRGALAIDTGIEGAPKRFVLEHRTSEKILDFCNAENIESLVRRGNATPEHVIHIKRFGVALPAPEKNR
LGEWAVRAREAVAAYQADYQAYFERNNARVGGGKRMLDPKPRVFYVAGIGLFAAGAARKNATVGADVAEATIDVITKAEG
IEAFEALSERDLFDIEYWSLEQVKLTKVQEKPLTRQVAIVTGAASGLGFAVAEALKAEGAELALFDISEDALNAAAKKLG
ALPVLCDVTSSEAVDAAVARVAQHYGGVDILISNAGAAFQGKLLSVDEATFRKAFDLNFWSHHYVARAVVRVMEQQKSGG
SLVFNVSKQAVNPGADFGPYGTSKAALMALMRQYAIEHGGSGITSNAVNADRIRTGLMTDKMVEERSMARGLTPEDYMRG
NMLRREVTGADVAAAFVHLAKARTSTGAVVTVDGGNVAAMMR
>Mature_682_residues
MKSRWSDSEFTSIIDAYVAKGVNRDLAIRTYTTRLLGSDPELVLHGGGNTSVKTTFTEMDGSEVDVLCVKGSGWDMGTIE
PQGLPAVRLQPLQAMIDFETLSDDDMVMLQRRLLVDPAAPNPSVEAILHAILPFKHIDHTHANAIVSLTNQPHGEDLIRE
LFPDAIIVPYVMPGFDLAKACDTAFKADPKGDGMILLKHGIFTWSEDPREAYEDMIAKIDKAERRLSQGRAKPFRSIAVP
AGLAAAADIAPILRGALAIDTGIEGAPKRFVLEHRTSEKILDFCNAENIESLVRRGNATPEHVIHIKRFGVALPAPEKNR
LGEWAVRAREAVAAYQADYQAYFERNNARVGGGKRMLDPKPRVFYVAGIGLFAAGAARKNATVGADVAEATIDVITKAEG
IEAFEALSERDLFDIEYWSLEQVKLTKVQEKPLTRQVAIVTGAASGLGFAVAEALKAEGAELALFDISEDALNAAAKKLG
ALPVLCDVTSSEAVDAAVARVAQHYGGVDILISNAGAAFQGKLLSVDEATFRKAFDLNFWSHHYVARAVVRVMEQQKSGG
SLVFNVSKQAVNPGADFGPYGTSKAALMALMRQYAIEHGGSGITSNAVNADRIRTGLMTDKMVEERSMARGLTPEDYMRG
NMLRREVTGADVAAAFVHLAKARTSTGAVVTVDGGNVAAMMR

Specific function: Unknown

COG id: COG3347

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=32.295719844358, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI126723191, Length=212, Percent_Identity=31.6037735849057, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=31.2169312169312, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=226, Percent_Identity=31.4159292035398, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=30.3643724696356, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI31542939, Length=215, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI302344755, Length=111, Percent_Identity=38.7387387387387, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=28.0487804878049, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI20149619, Length=250, Percent_Identity=28.4, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=27.9835390946502, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI40807363, Length=233, Percent_Identity=27.8969957081545, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI4758504, Length=129, Percent_Identity=35.6589147286822, Blast_Score=66, Evalue=1e-10,
Organism=Homo sapiens, GI83715985, Length=129, Percent_Identity=35.6589147286822, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=29.6442687747036, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=27.4193548387097, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=26.8595041322314, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787545, Length=266, Percent_Identity=30.0751879699248, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=24.8062015503876, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI87082160, Length=266, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=31.9047619047619, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=29.3040293040293, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=27.843137254902, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=217, Percent_Identity=29.9539170506912, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=208, Percent_Identity=29.8076923076923, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=29.296875, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=220, Percent_Identity=24.0909090909091, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355319, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644337, Length=249, Percent_Identity=32.5301204819277, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571387, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=29.0196078431373, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641232, Length=223, Percent_Identity=27.3542600896861, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR013454
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short; PF00596 Aldolase_II [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 73587; Mature: 73587

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRWSDSEFTSIIDAYVAKGVNRDLAIRTYTTRLLGSDPELVLHGGGNTSVKTTFTEMD
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCEEEECCCCCCEEEEEEECC
GSEVDVLCVKGSGWDMGTIEPQGLPAVRLQPLQAMIDFETLSDDDMVMLQRRLLVDPAAP
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
NPSVEAILHAILPFKHIDHTHANAIVSLTNQPHGEDLIRELFPDAIIVPYVMPGFDLAKA
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEECCCCCCCHHHHH
CDTAFKADPKGDGMILLKHGIFTWSEDPREAYEDMIAKIDKAERRLSQGRAKPFRSIAVP
HHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
AGLAAAADIAPILRGALAIDTGIEGAPKRFVLEHRTSEKILDFCNAENIESLVRRGNATP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCH
EHVIHIKRFGVALPAPEKNRLGEWAVRAREAVAAYQADYQAYFERNNARVGGGKRMLDPK
HHEEEEHHHCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCC
PRVFYVAGIGLFAAGAARKNATVGADVAEATIDVITKAEGIEAFEALSERDLFDIEYWSL
CCEEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCC
EQVKLTKVQEKPLTRQVAIVTGAASGLGFAVAEALKAEGAELALFDISEDALNAAAKKLG
CCEEEHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHC
ALPVLCDVTSSEAVDAAVARVAQHYGGVDILISNAGAAFQGKLLSVDEATFRKAFDLNFW
CCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCHHHHHHHHCCCCH
SHHYVARAVVRVMEQQKSGGSLVFNVSKQAVNPGADFGPYGTSKAALMALMRQYAIEHGG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SGITSNAVNADRIRTGLMTDKMVEERSMARGLTPEDYMRGNMLRREVTGADVAAAFVHLA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
KARTSTGAVVTVDGGNVAAMMR
HHCCCCCCEEEECCCCEEEEEC
>Mature Secondary Structure
MKSRWSDSEFTSIIDAYVAKGVNRDLAIRTYTTRLLGSDPELVLHGGGNTSVKTTFTEMD
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCEEEECCCCCCEEEEEEECC
GSEVDVLCVKGSGWDMGTIEPQGLPAVRLQPLQAMIDFETLSDDDMVMLQRRLLVDPAAP
CCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
NPSVEAILHAILPFKHIDHTHANAIVSLTNQPHGEDLIRELFPDAIIVPYVMPGFDLAKA
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEECCCCCCCHHHHH
CDTAFKADPKGDGMILLKHGIFTWSEDPREAYEDMIAKIDKAERRLSQGRAKPFRSIAVP
HHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
AGLAAAADIAPILRGALAIDTGIEGAPKRFVLEHRTSEKILDFCNAENIESLVRRGNATP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCH
EHVIHIKRFGVALPAPEKNRLGEWAVRAREAVAAYQADYQAYFERNNARVGGGKRMLDPK
HHEEEEHHHCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCC
PRVFYVAGIGLFAAGAARKNATVGADVAEATIDVITKAEGIEAFEALSERDLFDIEYWSL
CCEEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCC
EQVKLTKVQEKPLTRQVAIVTGAASGLGFAVAEALKAEGAELALFDISEDALNAAAKKLG
CCEEEHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHC
ALPVLCDVTSSEAVDAAVARVAQHYGGVDILISNAGAAFQGKLLSVDEATFRKAFDLNFW
CCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECCHHHHHHHHCCCCH
SHHYVARAVVRVMEQQKSGGSLVFNVSKQAVNPGADFGPYGTSKAALMALMRQYAIEHGG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SGITSNAVNADRIRTGLMTDKMVEERSMARGLTPEDYMRGNMLRREVTGADVAAAFVHLA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
KARTSTGAVVTVDGGNVAAMMR
HHCCCCCCEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 8188684 [H]