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The map label for this gene is ruvA [H]

Identifier: 150397836

GI number: 150397836

Start: 2740014

End: 2740631

Strand: Reverse

Name: ruvA [H]

Synonym: Smed_2638

Alternate gene names: 150397836

Gene position: 2740631-2740014 (Counterclockwise)

Preceding gene: 150397837

Following gene: 150397835

Centisome position: 72.47

GC content: 63.75

Gene sequence:

>618_bases
ATGATCGGCAAGCTGAAAGGCACCATAGACGAGATCGGCGAGGATCATGTGGTACTCGACGTGCATGGCGTCGGATATGT
CGCCCATTGTTCGGCGCGCACGCTCGCAAAGCTCGGAAGGGCGGGAGAGGCGGCCGTGCTCTTCATCGAGACCTATGTGC
GCGAGGATCAGCTGAAGCTGTTCGGCTTTCTGAGCGCATTGGAGCGTGAATGGTTCCGGCTGCTTCAGAGCGTTCAGGGT
GTGGGGTCCAAGGTCGCGCTGGCGGTTCTTTCCACGCTGACTCCGGGCGAACTCGCCAATGCCATCGCACTGCAGGACAA
GACGTCGATCTCGCGCGCGCCGGGTGTCGGCCCGAAAGTCGCCGTGCGCATCGTCACCGAACTCAAGAACAAGGCCCCCG
CTTTCGTCGGCGAGATGGCACCGTCGATCGGCCTAAAGCAGGAACTCGGGGAAGGCGTTGCCGCCGCGCCGGTCTCGGAT
GCGGTCTCGGCGCTCACCAATCTCGGCTATTCGCGCGACCAGGCTGCGAATGCCGTTGCAGCCGCGCTGAAAAACGGCGG
GGAGGGCGCCGACAGCGCCAGGCTGATCCGCCTTGGCCTCAAGGAACTGTCGCGGTGA

Upstream 100 bases:

>100_bases
GGCAGGCGATTACCAGCCGCCTCGCAGCGCTTGCAGGGTAGCCCGGCCATCGGTACTGCTTCAAAGGCGACGGATACCCA
ACCCCATCCAGAGAGACCAG

Downstream 100 bases:

>100_bases
GGGGGCGAGCCTTCCTGCGGCCACAAAGGCATTGGAGTACGGGTGCGCGGGCCGGCCCGGCCGATGCCGGTGGATTGATT
GGGGCGACCCTACTATGGTT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGKLKGTIDEIGEDHVVLDVHGVGYVAHCSARTLAKLGRAGEAAVLFIETYVREDQLKLFGFLSALEREWFRLLQSVQG
VGSKVALAVLSTLTPGELANAIALQDKTSISRAPGVGPKVAVRIVTELKNKAPAFVGEMAPSIGLKQELGEGVAAAPVSD
AVSALTNLGYSRDQAANAVAAALKNGGEGADSARLIRLGLKELSR

Sequences:

>Translated_205_residues
MIGKLKGTIDEIGEDHVVLDVHGVGYVAHCSARTLAKLGRAGEAAVLFIETYVREDQLKLFGFLSALEREWFRLLQSVQG
VGSKVALAVLSTLTPGELANAIALQDKTSISRAPGVGPKVAVRIVTELKNKAPAFVGEMAPSIGLKQELGEGVAAAPVSD
AVSALTNLGYSRDQAANAVAAALKNGGEGADSARLIRLGLKELSR
>Mature_205_residues
MIGKLKGTIDEIGEDHVVLDVHGVGYVAHCSARTLAKLGRAGEAAVLFIETYVREDQLKLFGFLSALEREWFRLLQSVQG
VGSKVALAVLSTLTPGELANAIALQDKTSISRAPGVGPKVAVRIVTELKNKAPAFVGEMAPSIGLKQELGEGVAAAPVSD
AVSALTNLGYSRDQAANAVAAALKNGGEGADSARLIRLGLKELSR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=207, Percent_Identity=34.2995169082126, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21385; Mature: 21385

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLKGTIDEIGEDHVVLDVHGVGYVAHCSARTLAKLGRAGEAAVLFIETYVREDQLKL
CCCCCCCCHHHCCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHH
FGFLSALEREWFRLLQSVQGVGSKVALAVLSTLTPGELANAIALQDKTSISRAPGVGPKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCHHH
AVRIVTELKNKAPAFVGEMAPSIGLKQELGEGVAAAPVSDAVSALTNLGYSRDQAANAVA
HHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
AALKNGGEGADSARLIRLGLKELSR
HHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLKGTIDEIGEDHVVLDVHGVGYVAHCSARTLAKLGRAGEAAVLFIETYVREDQLKL
CCCCCCCCHHHCCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHH
FGFLSALEREWFRLLQSVQGVGSKVALAVLSTLTPGELANAIALQDKTSISRAPGVGPKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCHHH
AVRIVTELKNKAPAFVGEMAPSIGLKQELGEGVAAAPVSDAVSALTNLGYSRDQAANAVA
HHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
AALKNGGEGADSARLIRLGLKELSR
HHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]