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The map label for this gene is ruvB [H]

Identifier: 150397835

GI number: 150397835

Start: 2738799

End: 2739839

Strand: Reverse

Name: ruvB [H]

Synonym: Smed_2637

Alternate gene names: 150397835

Gene position: 2739839-2738799 (Counterclockwise)

Preceding gene: 150397836

Following gene: 150397834

Centisome position: 72.45

GC content: 64.94

Gene sequence:

>1041_bases
ATGAGTGAAGCCGCACGCCTGATTGCGCCGGAAAAGCGAGGGGAAGACGTCGATGCGACCTTGCGCCCGCAGACGCTCGA
CGAGTTCACCGGTCAGGCAGAAGCACGCGCCAATCTCAAGATCTTCATCGAAGCGGCGCGCAATCGCGGCGAAGCGCTCG
ACCACGTGCTGTTCGTCGGCCCCCCCGGGCTAGGCAAGACGACGCTGGCGCAGATCATGGCGAAGGAGCTCGGCGTTAAT
TTTCGCTCGACCTCCGGCCCGGTGATCGCAAAGGCCGGCGATCTTGCCGCGTTGCTGACCAACCTCGAAGAGCGCGACGT
GCTCTTCATCGATGAAATTCATCGTCTCAACCCGGCCGTCGAGGAGATACTCTATCCGGCCATGGAGGATTTTCAGCTCG
ACCTCATCATCGGCGAGGGCCCGTCGGCCCGTTCGGTGAAAATCGACCTGGCCAAGTTCACGCTGGTTGCCGCGACGACG
CGCCTCGGTCTTCTCACGACGCCGCTGCGCGACCGGTTCGGCATCCCCGTACGGCTCAATTTCTATACCGTCGAGGAGCT
GGAGCTGATCGTGCGCCGTGGCGCGCGGCTGATGGGCCTCGGCATGACCGACGAAGGTGCGCGCGAAATCGCCCGCCGTG
CGCGCGGCACGCCCCGAATCGCCGGCCGTCTTCTGCGCCGTGTGCGCGACTTCGCCGAGGTCGCGCGGGCGGAGGCCGTA
ACGCGCCAGATTGCCGACGAGGCGCTGACCCGGCTCCTCGTGGACAGCATGGGCCTCGACCAGCTCGACCGGCGCTATCT
GACGATGATCGCCCAGAATTTCGGCGGCGGGCCGGTCGGAATCGAGACCATCGCCGCAGGCTTGTCCGAGCCGCGCGACG
CGATCGAAGATATCATCGAGCCCTATCTGATCCAGCAGGGATTCATCCAGCGCACCCCCCGCGGCCGGGTTTTGACGGCG
AATGCCTGGAAGCATCTCGGCCTCAACCCTCCAAAGGATGTCGAGGCGAGCCAATTCCGCCTAACGCTCGAGGACGACTG
A

Upstream 100 bases:

>100_bases
TTGATTGGGGCGACCCTACTATGGTTGGGCGCAGAAGAGGTGGTGTTCGGCTTCAACGACCCGCATCATGACGCCGACAG
CCTGAAACGGAAGCTTTGAC

Downstream 100 bases:

>100_bases
CATGTTCACCCGGCGGGGCTTCGTGAAACTTCTGGGCGGTGGATTTTTCGGCGCCATGGCGCTTGGCGGCTATGCCTTTG
GCGTTGAGCCGTTGGCGCGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSEAARLIAPEKRGEDVDATLRPQTLDEFTGQAEARANLKIFIEAARNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPSARSVKIDLAKFTLVAATT
RLGLLTTPLRDRFGIPVRLNFYTVEELELIVRRGARLMGLGMTDEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
TRQIADEALTRLLVDSMGLDQLDRRYLTMIAQNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLTA
NAWKHLGLNPPKDVEASQFRLTLEDD

Sequences:

>Translated_346_residues
MSEAARLIAPEKRGEDVDATLRPQTLDEFTGQAEARANLKIFIEAARNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPSARSVKIDLAKFTLVAATT
RLGLLTTPLRDRFGIPVRLNFYTVEELELIVRRGARLMGLGMTDEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
TRQIADEALTRLLVDSMGLDQLDRRYLTMIAQNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLTA
NAWKHLGLNPPKDVEASQFRLTLEDD
>Mature_345_residues
SEAARLIAPEKRGEDVDATLRPQTLDEFTGQAEARANLKIFIEAARNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPSARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPVRLNFYTVEELELIVRRGARLMGLGMTDEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAVT
RQIADEALTRLLVDSMGLDQLDRRYLTMIAQNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLTAN
AWKHLGLNPPKDVEASQFRLTLEDD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=62.874251497006, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38180; Mature: 38049

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAARLIAPEKRGEDVDATLRPQTLDEFTGQAEARANLKIFIEAARNRGEALDHVLFVG
CCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEEEEHHCCCHHHCEEEEEC
PPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPSARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLN
HHHHHHHHHCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHEECCHHHHCCCCEEEE
FYTVEELELIVRRGARLMGLGMTDEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
EEEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TRQIADEALTRLLVDSMGLDQLDRRYLTMIAQNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
PYLIQQGFIQRTPRGRVLTANAWKHLGLNPPKDVEASQFRLTLEDD
HHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
SEAARLIAPEKRGEDVDATLRPQTLDEFTGQAEARANLKIFIEAARNRGEALDHVLFVG
CCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEEEEHHCCCHHHCEEEEEC
PPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDFQLDLIIGEGPSARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLN
HHHHHHHHHCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHEECCHHHHCCCCEEEE
FYTVEELELIVRRGARLMGLGMTDEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAV
EEEHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TRQIADEALTRLLVDSMGLDQLDRRYLTMIAQNFGGGPVGIETIAAGLSEPRDAIEDIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHH
PYLIQQGFIQRTPRGRVLTANAWKHLGLNPPKDVEASQFRLTLEDD
HHHHHHHHHHCCCCCCEEECCCHHHCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA