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The map label for this gene is galE [H]

Identifier: 150397833

GI number: 150397833

Start: 2736961

End: 2737866

Strand: Direct

Name: galE [H]

Synonym: Smed_2635

Alternate gene names: 150397833

Gene position: 2736961-2737866 (Clockwise)

Preceding gene: 150397832

Following gene: 150397838

Centisome position: 72.37

GC content: 65.01

Gene sequence:

>906_bases
ATGAGCAGCGCCGCCACGACGCGCGTTCTCATCTCCGGCGGAACCGGATTCGTCGGCCGCTTCATCGTCGAGCACCTGCT
GGCAAACGGCTATCACGTCACGGTCGGCGGCCGCTCTCCGCCTCCTGCCGGCTTCTATTCGCAACCGGTTTCCCATGTGC
CGCTCCGGCTCGACCCCGACGCGGACCAGGCCCGCGCATTCGACAATATCTGTTACTTTGTCCATGCCGCCTTCGAGCAT
GTCGAGGGCAGATATCGTGGAGGCGAGGGGCAGGACCCTGAGGGATTCCGCCGCGCCAATCTCGAGGGCTCGGTCCGCCT
CTTCGAGGAGGCGCGCACCGCCGGCGTGCGCCGCTGCGTTTTCCTGTCGAGCCGCGCCGCCTATGGCGACACGGCGCCGC
CGGTTGTCGCAGAAACGTCACCCGTCGCACCGGACACGCTCTACGGACAGGTGAAGCTCGCCGCCGAAAATGCCTTGAAG
TCGATGACCGGGCATCATTTCGTCACGGCGAACCTGCGGATAACAGGCGTTTACGGGCCTGCGGGTGAAGGGCGACAGCA
TAAATGGAGCGATCTCTTCGCCGACTATCTCGCCGGCCGAACCGTGCCGGACCGCATCGGCACCGAAGTGCATGGCGATG
ACGTCGCCAAGGCTGTCCGCCTCATGCTCGAAACCGAGCCCGCGAGACTATCCGGCCAGGTCTTCAACGTCTCCGACGTG
CTGACCGGCAACCGCGAGATCCTCTCCATTCTCCAGGCTGCAACGGGTTGTCCAAACCCCCTGCCCACAGCGGCAGCGGC
CGAATTCACGACGATGTCGACGGAGAAGCTGCGCGCTCTCGGCTGGGTGCCGGGCGGAAGGGAAAAACTCGCTGCGACAA
TCCGTGAACTTGCGGGGAGACGGTGA

Upstream 100 bases:

>100_bases
TGCGGCCTTTGATCGATCTCTGGCATGCATATCTGACGGGCGACCGGATTCCCGATATTGCCGCTCTCGCCAACCCGGCG
CACGCCGGCCCCACGTCCCC

Downstream 100 bases:

>100_bases
CCGGTAGGCGGAGACGGGGCGATTCCACTCACCCGATATCAACGACCACAATCTCCGGCGGCACGCCAAAACGGATCGGG
GCGATGGAGCAGCCAAGGCC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSAATTRVLISGGTGFVGRFIVEHLLANGYHVTVGGRSPPPAGFYSQPVSHVPLRLDPDADQARAFDNICYFVHAAFEH
VEGRYRGGEGQDPEGFRRANLEGSVRLFEEARTAGVRRCVFLSSRAAYGDTAPPVVAETSPVAPDTLYGQVKLAAENALK
SMTGHHFVTANLRITGVYGPAGEGRQHKWSDLFADYLAGRTVPDRIGTEVHGDDVAKAVRLMLETEPARLSGQVFNVSDV
LTGNREILSILQAATGCPNPLPTAAAAEFTTMSTEKLRALGWVPGGREKLAATIRELAGRR

Sequences:

>Translated_301_residues
MSSAATTRVLISGGTGFVGRFIVEHLLANGYHVTVGGRSPPPAGFYSQPVSHVPLRLDPDADQARAFDNICYFVHAAFEH
VEGRYRGGEGQDPEGFRRANLEGSVRLFEEARTAGVRRCVFLSSRAAYGDTAPPVVAETSPVAPDTLYGQVKLAAENALK
SMTGHHFVTANLRITGVYGPAGEGRQHKWSDLFADYLAGRTVPDRIGTEVHGDDVAKAVRLMLETEPARLSGQVFNVSDV
LTGNREILSILQAATGCPNPLPTAAAAEFTTMSTEKLRALGWVPGGREKLAATIRELAGRR
>Mature_300_residues
SSAATTRVLISGGTGFVGRFIVEHLLANGYHVTVGGRSPPPAGFYSQPVSHVPLRLDPDADQARAFDNICYFVHAAFEHV
EGRYRGGEGQDPEGFRRANLEGSVRLFEEARTAGVRRCVFLSSRAAYGDTAPPVVAETSPVAPDTLYGQVKLAAENALKS
MTGHHFVTANLRITGVYGPAGEGRQHKWSDLFADYLAGRTVPDRIGTEVHGDDVAKAVRLMLETEPARLSGQVFNVSDVL
TGNREILSILQAATGCPNPLPTAAAAEFTTMSTEKLRALGWVPGGREKLAATIRELAGRR

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 32299; Mature: 32168

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAATTRVLISGGTGFVGRFIVEHLLANGYHVTVGGRSPPPAGFYSQPVSHVPLRLDPD
CCCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEECCC
ADQARAFDNICYFVHAAFEHVEGRYRGGEGQDPEGFRRANLEGSVRLFEEARTAGVRRCV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
FLSSRAAYGDTAPPVVAETSPVAPDTLYGQVKLAAENALKSMTGHHFVTANLRITGVYGP
EEECCCCCCCCCCCCEECCCCCCCCHHHHEEEEHHHHHHHHHCCCEEEEEEEEEEEEECC
AGEGRQHKWSDLFADYLAGRTVPDRIGTEVHGDDVAKAVRLMLETEPARLSGQVFNVSDV
CCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHCCEEEEHHHH
LTGNREILSILQAATGCPNPLPTAAAAEFTTMSTEKLRALGWVPGGREKLAATIRELAGR
HCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHCC
R
C
>Mature Secondary Structure 
SSAATTRVLISGGTGFVGRFIVEHLLANGYHVTVGGRSPPPAGFYSQPVSHVPLRLDPD
CCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEECCC
ADQARAFDNICYFVHAAFEHVEGRYRGGEGQDPEGFRRANLEGSVRLFEEARTAGVRRCV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
FLSSRAAYGDTAPPVVAETSPVAPDTLYGQVKLAAENALKSMTGHHFVTANLRITGVYGP
EEECCCCCCCCCCCCEECCCCCCCCHHHHEEEEHHHHHHHHHCCCEEEEEEEEEEEEECC
AGEGRQHKWSDLFADYLAGRTVPDRIGTEVHGDDVAKAVRLMLETEPARLSGQVFNVSDV
CCCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCHHCCEEEEHHHH
LTGNREILSILQAATGCPNPLPTAAAAEFTTMSTEKLRALGWVPGGREKLAATIRELAGR
HCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3335481 [H]