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The map label for this gene is 150397728

Identifier: 150397728

GI number: 150397728

Start: 2628334

End: 2628912

Strand: Direct

Name: 150397728

Synonym: Smed_2530

Alternate gene names: NA

Gene position: 2628334-2628912 (Clockwise)

Preceding gene: 150397727

Following gene: 150397729

Centisome position: 69.5

GC content: 63.21

Gene sequence:

>579_bases
ATGGTGAAATTGAACAAGATCTACACCCGGACCGGCGACAACGGCACGACTGGCCTCGTCTCCGGTCCACGCCGCCTGAA
AAGCGATCTCCGGGTGGAAGCCTATGGTGCCATAGACGAGGCGAATGCCTTTGTGGGACTCGCCCGCCAGCACACCCATG
CGATGCCTGACCTCGACGCAACGCTCATGCGCGTTCAGAACGACCTTTTCGATCTTGGAGCCGATCTCGCGACGCCGGAC
ACGGGTGAAAAACCCGAATACGAACCGCTGCGCATCGTCGCCGCCCAGGTCGCGCGCCTGGAAGAGGAGATCGACAGGCT
GAATGCCGACCTCGAACCGTTGCGCTCGTTCGTGCTTCCCGCCGGCAGCGCCGCTTCCGCCGCACTCCATGTGGCCCGTA
CGGTAGCGCGCCGCGCCGAGCGGCAAATGGTCGCGCTCTCCCGCGTGGAGGGCGAAGTCGTCAGCGCCGAGGCGGTTGCC
TATGTCAACCGTCTTTCAGATTTCCTGTTCGTCGCGGCCCGCTGGACGAATGACAAGGGACATGCCGACGTTCTCTGGGT
TCCCGGCAAGAACAGATGA

Upstream 100 bases:

>100_bases
TCTGGGTAACCGGCGGCGGTCGTCCGGGCTAGCAGGAAAGTGGGCGGTCATGGATCAACCACGCACATAAGAACAATGAC
CCGGGGATAGCGACAGCGCC

Downstream 100 bases:

>100_bases
TGGACTTTCGAAAGTTTGCGCTCTTTCCTCCGGCATGATTCCAGTTCACCCGGTCTAAAATCATCGTGATCTGATCGGAT
ACGCCTACAAAGACACGTTG

Product: ATP--cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MVKLNKIYTRTGDNGTTGLVSGPRRLKSDLRVEAYGAIDEANAFVGLARQHTHAMPDLDATLMRVQNDLFDLGADLATPD
TGEKPEYEPLRIVAAQVARLEEEIDRLNADLEPLRSFVLPAGSAASAALHVARTVARRAERQMVALSRVEGEVVSAEAVA
YVNRLSDFLFVAARWTNDKGHADVLWVPGKNR

Sequences:

>Translated_192_residues
MVKLNKIYTRTGDNGTTGLVSGPRRLKSDLRVEAYGAIDEANAFVGLARQHTHAMPDLDATLMRVQNDLFDLGADLATPD
TGEKPEYEPLRIVAAQVARLEEEIDRLNADLEPLRSFVLPAGSAASAALHVARTVARRAERQMVALSRVEGEVVSAEAVA
YVNRLSDFLFVAARWTNDKGHADVLWVPGKNR
>Mature_192_residues
MVKLNKIYTRTGDNGTTGLVSGPRRLKSDLRVEAYGAIDEANAFVGLARQHTHAMPDLDATLMRVQNDLFDLGADLATPD
TGEKPEYEPLRIVAAQVARLEEEIDRLNADLEPLRSFVLPAGSAASAALHVARTVARRAERQMVALSRVEGEVVSAEAVA
YVNRLSDFLFVAARWTNDKGHADVLWVPGKNR

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=195, Percent_Identity=36.9230769230769, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115534154, Length=169, Percent_Identity=39.0532544378698, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21020; Mature: 21020

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLNKIYTRTGDNGTTGLVSGPRRLKSDLRVEAYGAIDEANAFVGLARQHTHAMPDLDA
CCCCCCEEEECCCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCCHHH
TLMRVQNDLFDLGADLATPDTGEKPEYEPLRIVAAQVARLEEEIDRLNADLEPLRSFVLP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
AGSAASAALHVARTVARRAERQMVALSRVEGEVVSAEAVAYVNRLSDFLFVAARWTNDKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCC
HADVLWVPGKNR
CEEEEECCCCCC
>Mature Secondary Structure
MVKLNKIYTRTGDNGTTGLVSGPRRLKSDLRVEAYGAIDEANAFVGLARQHTHAMPDLDA
CCCCCCEEEECCCCCCCCCCCCHHHHHHHCCEEEECCHHHHHHHHHHHHHHHCCCCCHHH
TLMRVQNDLFDLGADLATPDTGEKPEYEPLRIVAAQVARLEEEIDRLNADLEPLRSFVLP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
AGSAASAALHVARTVARRAERQMVALSRVEGEVVSAEAVAYVNRLSDFLFVAARWTNDKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCC
HADVLWVPGKNR
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]