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The map label for this gene is yfjP [H]

Identifier: 150397723

GI number: 150397723

Start: 2624555

End: 2625202

Strand: Reverse

Name: yfjP [H]

Synonym: Smed_2525

Alternate gene names: 150397723

Gene position: 2625202-2624555 (Counterclockwise)

Preceding gene: 150397725

Following gene: 150397722

Centisome position: 69.41

GC content: 66.2

Gene sequence:

>648_bases
ATGCGAATCATCCGGACGCACGAGGACATAGAGGCCGGAATCGCCGGTCTGGTGCTGCTCGATGCCCGGCTCGAACATGT
CGTCGGGAAGGCGGGGCCGGTGCCGTTGAGGCGCACCGACCCCGGTTACCGGGGACTTGCCAACATAATCGTGTCGCAGA
TGGTCTCGAAAGCGAGTGCGGCGGCGATCTGGAAGCGGATGGAGTCCTTGCTTGGGGAGATCACTGCAGACGCGGTGCTT
GCGCTCGACGATGACGATTGCCGGCGCTTGGGCCTGTCCCGTGCCAAGGCCGATACGCTCAGGCGCACCGCGGCCGCCGC
GGTAGCCGGCGAAATCGACCTGCATGCCATCTGCGACGTCCAAGCGCCCGCGGCGATCCACGAATTGACTGCGATCAAGG
GCATCGGCCGGTGGACTGCCGAAGTCTATCTGCTTTTCTGCGCCGGTCATCCGGACGTCTTCCCCGCCGGCGACGTCGCC
CTGCAGAATGCCATCGGCCACGCGCTGGGGTTCGAACTGCGCCCCACGGCAAGCGAGGTCGATTCGCTCGCTGCCGCATG
GTCGCCGTGGCGCAGCGTCGCCGCGCGGCTTTTTTGGGCCTATTATGCGCAGGAAATGCGCCGCGATGCGCTCCCCGTGG
TGCCCTGA

Upstream 100 bases:

>100_bases
TCGGCGCAAAGCGAAAAACCGGTTGCTCTGGTCGTGAAATCGGCATCGTTTTGCTTTGCCATGGAAGCGATATAAATATC
ACTTTTTTTTTGGAGGACGC

Downstream 100 bases:

>100_bases
AGAAAAAAGGCGGATGCTTTACTCCCTTTTCTTTGTGGCTTCACAATCCTGTCGCAACGCGCCTAATATAGAAGATGCAG
ATGCCGAATCGCTCAGGAGA

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRIIRTHEDIEAGIAGLVLLDARLEHVVGKAGPVPLRRTDPGYRGLANIIVSQMVSKASAAAIWKRMESLLGEITADAVL
ALDDDDCRRLGLSRAKADTLRRTAAAAVAGEIDLHAICDVQAPAAIHELTAIKGIGRWTAEVYLLFCAGHPDVFPAGDVA
LQNAIGHALGFELRPTASEVDSLAAAWSPWRSVAARLFWAYYAQEMRRDALPVVP

Sequences:

>Translated_215_residues
MRIIRTHEDIEAGIAGLVLLDARLEHVVGKAGPVPLRRTDPGYRGLANIIVSQMVSKASAAAIWKRMESLLGEITADAVL
ALDDDDCRRLGLSRAKADTLRRTAAAAVAGEIDLHAICDVQAPAAIHELTAIKGIGRWTAEVYLLFCAGHPDVFPAGDVA
LQNAIGHALGFELRPTASEVDSLAAAWSPWRSVAARLFWAYYAQEMRRDALPVVP
>Mature_215_residues
MRIIRTHEDIEAGIAGLVLLDARLEHVVGKAGPVPLRRTDPGYRGLANIIVSQMVSKASAAAIWKRMESLLGEITADAVL
ALDDDDCRRLGLSRAKADTLRRTAAAAVAGEIDLHAICDVQAPAAIHELTAIKGIGRWTAEVYLLFCAGHPDVFPAGDVA
LQNAIGHALGFELRPTASEVDSLAAAWSPWRSVAARLFWAYYAQEMRRDALPVVP

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23152; Mature: 23152

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIRTHEDIEAGIAGLVLLDARLEHVVGKAGPVPLRRTDPGYRGLANIIVSQMVSKASA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAIWKRMESLLGEITADAVLALDDDDCRRLGLSRAKADTLRRTAAAAVAGEIDLHAICDV
HHHHHHHHHHHHHHHHCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
QAPAAIHELTAIKGIGRWTAEVYLLFCAGHPDVFPAGDVALQNAIGHALGFELRPTASEV
CCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
DSLAAAWSPWRSVAARLFWAYYAQEMRRDALPVVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRIIRTHEDIEAGIAGLVLLDARLEHVVGKAGPVPLRRTDPGYRGLANIIVSQMVSKASA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAIWKRMESLLGEITADAVLALDDDDCRRLGLSRAKADTLRRTAAAAVAGEIDLHAICDV
HHHHHHHHHHHHHHHHCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
QAPAAIHELTAIKGIGRWTAEVYLLFCAGHPDVFPAGDVALQNAIGHALGFELRPTASEV
CCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
DSLAAAWSPWRSVAARLFWAYYAQEMRRDALPVVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]