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The map label for this gene is argJ [H]

Identifier: 150397714

GI number: 150397714

Start: 2611277

End: 2612518

Strand: Reverse

Name: argJ [H]

Synonym: Smed_2516

Alternate gene names: 150397714

Gene position: 2612518-2611277 (Counterclockwise)

Preceding gene: 150397715

Following gene: 150397713

Centisome position: 69.08

GC content: 65.06

Gene sequence:

>1242_bases
ATGTCCGGTTCCGTCTCTCCGCTTGCTCCGAAGACCTTCGCCGAAATGCCTGCCCTGCGCGGCGTACGCATGGCAACCGC
TGCCGCAGGGATCAAGTACAAGAACCGTACGGACGTATTGATGATGCTCTTCGACCGGCCGGCATCCGTCGCCGGCGTGT
TCACGCGGTCGAAGTGCCCCTCCGCACCGGTCGACCACTGCCGCCAGAACCTGCCGGGCGGCGTTGCGCGCGCCGTCGTC
GTCAATTCGGGCAATGCCAACGCATTCACCGGCAAGAAGGGCAGGGAGGCCACCAAGCTGACCGCCGAGGCCGCGGCCAG
GGCGGTCGGCTGCAGCGAGGCGGAGGTATTTCTGGCGTCGACGGGCGTTATCGGCGAGCCGCTCGACGCCACCAAGTTCG
CCGGTGTCCTCGATAAGCTTGCCGCGTCGGCCACCGAAGACCTGTGGTTCGAAGCGGCCAAAGCGATCATGACGACCGAT
ACCTATCCCAAGGTCGCCACCCGCAGCGCCGACATCGGCGGCATCAGTGTCGTGCTCAACGGGATTGCCAAAGGCGCCGG
GATGATCGCGCCGGACATGGCGACCATGCTGTCCTTCGTCGTCACCGACGCCGATATCGCTCCGGCGGCGCTTCAGGCGC
TGCTTTCGGCCGGAGTCGGACCGACCTTCAATTCGGTGACTGTCGACAGCGACACATCCACCTCGGACACGCTGATGCTG
TTTGCAACCGGTGCGGCGGCAGACGATGGCCAGGTAAGGGTAGAAGATGCGGCCGACGCGCGTCTCGACGCCTTCCGCAT
CGCGCTCAACGATCTGCTGCGCGATCTCGCGCTGCAGGTGGTGCGCGACGGCGAGGGGGCACGCAAGATGGTCGAGGTGA
CCGTCGAGGGCGCAGAGAACGATTCCGCGGCGAAACGCATTGCCCTTTCGATAGCCAATTCGCCGCTCGTCAAAACGGCG
GTTGCCGGCGAGGATGCCAATTGGGGCCGCGTCGTCATGGCGGTCGGCAAGGCCGGCGAAATGGCCGAGCGTGACCGGCT
GGCGATCTGGTTCGGCGATATCCGCGTAGCGGTCGAGGGCGAGCGCGATCCGGCCTATTCCGAAGCGGCCGCGAGTGCGG
TGATGCAGGGCGAGACCATTCCGATCCGTGTCGATATCGGTATCGGCTCGGGCCGTGCCACGGTCTACACCTGCGATCTG
ACCAAGGAATATGTGGAAATCAACGGCGACTACAGAAGCTGA

Upstream 100 bases:

>100_bases
TTGCTCCGCTCGCCTTTAAAAGACCAGGATGCCCGACGGCTGAACGCCGTTCGGGCATTTCGCGCAACATTCGAGACTTC
TGAAAAACAGGTTTGATTCA

Downstream 100 bases:

>100_bases
GCCGGTCGGGGAGATGAGATCGGAACGTGGCTGGAGAGCTGCGGACGCTTTCCCGACGGCACGGCAGTCAAGGCTACGAA
CATGACATCTGATGACAGAG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCPSAPVDHCRQNLPGGVARAVV
VNSGNANAFTGKKGREATKLTAEAAARAVGCSEAEVFLASTGVIGEPLDATKFAGVLDKLAASATEDLWFEAAKAIMTTD
TYPKVATRSADIGGISVVLNGIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLSAGVGPTFNSVTVDSDTSTSDTLML
FATGAAADDGQVRVEDAADARLDAFRIALNDLLRDLALQVVRDGEGARKMVEVTVEGAENDSAAKRIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEMAERDRLAIWFGDIRVAVEGERDPAYSEAAASAVMQGETIPIRVDIGIGSGRATVYTCDL
TKEYVEINGDYRS

Sequences:

>Translated_413_residues
MSGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCPSAPVDHCRQNLPGGVARAVV
VNSGNANAFTGKKGREATKLTAEAAARAVGCSEAEVFLASTGVIGEPLDATKFAGVLDKLAASATEDLWFEAAKAIMTTD
TYPKVATRSADIGGISVVLNGIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLSAGVGPTFNSVTVDSDTSTSDTLML
FATGAAADDGQVRVEDAADARLDAFRIALNDLLRDLALQVVRDGEGARKMVEVTVEGAENDSAAKRIALSIANSPLVKTA
VAGEDANWGRVVMAVGKAGEMAERDRLAIWFGDIRVAVEGERDPAYSEAAASAVMQGETIPIRVDIGIGSGRATVYTCDL
TKEYVEINGDYRS
>Mature_412_residues
SGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCPSAPVDHCRQNLPGGVARAVVV
NSGNANAFTGKKGREATKLTAEAAARAVGCSEAEVFLASTGVIGEPLDATKFAGVLDKLAASATEDLWFEAAKAIMTTDT
YPKVATRSADIGGISVVLNGIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLSAGVGPTFNSVTVDSDTSTSDTLMLF
ATGAAADDGQVRVEDAADARLDAFRIALNDLLRDLALQVVRDGEGARKMVEVTVEGAENDSAAKRIALSIANSPLVKTAV
AGEDANWGRVVMAVGKAGEMAERDRLAIWFGDIRVAVEGERDPAYSEAAASAVMQGETIPIRVDIGIGSGRATVYTCDLT
KEYVEINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=427, Percent_Identity=36.5339578454333, Blast_Score=237, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42902; Mature: 42771

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCP
CCCCCCCCCCHHHHHCHHHCCCHHHHHHHCCEECCCCCEEEEEECCCCCHHEEEECCCCC
SAPVDHCRQNLPGGVARAVVVNSGNANAFTGKKGREATKLTAEAAARAVGCSEAEVFLAS
CCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
TGVIGEPLDATKFAGVLDKLAASATEDLWFEAAKAIMTTDTYPKVATRSADIGGISVVLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHH
GIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLSAGVGPTFNSVTVDSDTSTSDTLML
HHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGAAADDGQVRVEDAADARLDAFRIALNDLLRDLALQVVRDGEGARKMVEVTVEGAEN
EEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
DSAAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEMAERDRLAIWFGDIRVAVEG
CHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEEEC
ERDPAYSEAAASAVMQGETIPIRVDIGIGSGRATVYTCDLTKEYVEINGDYRS
CCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCC
>Mature Secondary Structure 
SGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCP
CCCCCCCCCHHHHHCHHHCCCHHHHHHHCCEECCCCCEEEEEECCCCCHHEEEECCCCC
SAPVDHCRQNLPGGVARAVVVNSGNANAFTGKKGREATKLTAEAAARAVGCSEAEVFLAS
CCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
TGVIGEPLDATKFAGVLDKLAASATEDLWFEAAKAIMTTDTYPKVATRSADIGGISVVLN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHHHH
GIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLSAGVGPTFNSVTVDSDTSTSDTLML
HHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGAAADDGQVRVEDAADARLDAFRIALNDLLRDLALQVVRDGEGARKMVEVTVEGAEN
EEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
DSAAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEMAERDRLAIWFGDIRVAVEG
CHHHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEEEEC
ERDPAYSEAAASAVMQGETIPIRVDIGIGSGRATVYTCDLTKEYVEINGDYRS
CCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]