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The map label for this gene is grx [H]

Identifier: 150397707

GI number: 150397707

Start: 2606815

End: 2607072

Strand: Reverse

Name: grx [H]

Synonym: Smed_2509

Alternate gene names: 150397707

Gene position: 2607072-2606815 (Counterclockwise)

Preceding gene: 150397708

Following gene: 150397706

Centisome position: 68.94

GC content: 57.75

Gene sequence:

>258_bases
ATGGCCTCGGTCGTCATTTATACGCGTCAGTTCTGCGGCTATTGCACGAGAGCGAAGAGGCTTCTGGAGAGCAAAGGCGT
CGACTTCATCGAGTATGACGCCACCTATGCGCCGGAACTGCGTCAGGAAATGATCGAAAAATCCAAGGGTGGCAGGACCT
TCCCGCAGATCATCATCAATGACGTCCCTGTCGGCGGCTGCGATGATCTGCATGCGCTCGACCGCGCCGGCAAGCTTGAC
GATCTGCTCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGACGTTACGGTTTTGACCTTTGCAATGGCGGTGTCCGGTCCTATATGACAGGCAAAAGACATCCGGCGATCGATGCCGG
CAAAGGAGCGGTTGGAGACT

Downstream 100 bases:

>100_bases
CGCAAAGGTGGCGGCGTGGGCCCGCCCCCCATCAGAAGAGCATTGAATAGCAATGCGGGATCGTTCCGATCCAGGAAGTT
CGCTTGGGAGAAAGAATGCG

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MASVVIYTRQFCGYCTRAKRLLESKGVDFIEYDATYAPELRQEMIEKSKGGRTFPQIIINDVPVGGCDDLHALDRAGKLD
DLLAA

Sequences:

>Translated_85_residues
MASVVIYTRQFCGYCTRAKRLLESKGVDFIEYDATYAPELRQEMIEKSKGGRTFPQIIINDVPVGGCDDLHALDRAGKLD
DLLAA
>Mature_84_residues
ASVVIYTRQFCGYCTRAKRLLESKGVDFIEYDATYAPELRQEMIEKSKGGRTFPQIIINDVPVGGCDDLHALDRAGKLDD
LLAA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=81, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9469; Mature: 9338

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVVIYTRQFCGYCTRAKRLLESKGVDFIEYDATYAPELRQEMIEKSKGGRTFPQIIIN
CCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHC
DVPVGGCDDLHALDRAGKLDDLLAA
CCCCCCCCHHHHHHHCCCHHHHHCC
>Mature Secondary Structure 
ASVVIYTRQFCGYCTRAKRLLESKGVDFIEYDATYAPELRQEMIEKSKGGRTFPQIIIN
CCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHC
DVPVGGCDDLHALDRAGKLDDLLAA
CCCCCCCCHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]