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The map label for this gene is yafV [C]

Identifier: 150397706

GI number: 150397706

Start: 2605857

End: 2606714

Strand: Reverse

Name: yafV [C]

Synonym: Smed_2508

Alternate gene names: 150397706

Gene position: 2606714-2605857 (Counterclockwise)

Preceding gene: 150397707

Following gene: 150397705

Centisome position: 68.93

GC content: 63.64

Gene sequence:

>858_bases
ATGATGTTCAAGGCCGCCGCCGTCCAGATGTGCTCGGGGGTCGACCCCGCAAGGAATGCCGAGACGATGGCGGAGCTGGT
GCGCGAAGCGGCATTGCGAGGGGCAGGCTATGTCCAGACGCCGGAGATGACCGGAGCGATCCAGCGCGACCGGTCAGGCC
TGCGGAGCATATTGCGGGACGAGGCGAACGATATCGTCGTTCGGAAGGCTGCCCGCCTTGCCGGCGAACTCGCCATCTAT
CTGCATGTGGGCTCGACGCCGATCGCGCTCGCCGACGGCAAGATTGCCAATCGCGGCTTCCTGTTCGGGCCCGATGGCGC
TAAGATCTGTGAATACGACAAGATCCACATGTTCGACGTGGACCTTGAGAATGGCGAGAGCTGGCGCGAAAGCGCCGCCT
ATCATCCCGGTGCGACCGCCCGTATCGCAGATCTGCCGTTCGGCAAGCTGGGTTTTTCGATCTGCTACGATGTCCGCTTC
CCCGAACTTTTCCGACAGCAGGCGGTGGCCGGGGCCGAGATCATGTCGGTGCCCGCGGCGTTTACACGCCAGACCGGCGA
GGCGCATTGGGAGATACTCCTGCGGGCTCGCGCAATTGAAAACGGGCTCTTCGTCGTTGCCGCGGCTCAGGGAGGCACGC
ATGAGGACGGGCGGGAGACCTTCGGCCACTCGATGATCATCGATCCGTGGGGCAGGGTGCTTGCTCAAGCCGGTCGGACC
GGCGAGGAGATCATCATCGCAGAGATCGATCCATTGGCGGTGCACACGGCCCGCGCTAAGATCCCCAACCTCAAGAACGC
GCGCAGCTTCGTTCTGGATGAGGTGGTCCCGGCCGGAAAAGGAGGCGCTGCAGCTTGA

Upstream 100 bases:

>100_bases
CGCAAAGGTGGCGGCGTGGGCCCGCCCCCCATCAGAAGAGCATTGAATAGCAATGCGGGATCGTTCCGATCCAGGAAGTT
CGCTTGGGAGAAAGAATGCG

Downstream 100 bases:

>100_bases
TCCACTACACTCTTGCCTGTGACAAGGGCCACGACTTCGAGGGCTGGTTCTCGTCGAGCGATGATTTCGACCGGCAAGTC
GCGGCGCGCCTGGTCACGTG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MMFKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEANDIVVRKAARLAGELAIY
LHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDVDLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRF
PELFRQQAVAGAEIMSVPAAFTRQTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT
GEEIIIAEIDPLAVHTARAKIPNLKNARSFVLDEVVPAGKGGAAA

Sequences:

>Translated_285_residues
MMFKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEANDIVVRKAARLAGELAIY
LHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDVDLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRF
PELFRQQAVAGAEIMSVPAAFTRQTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT
GEEIIIAEIDPLAVHTARAKIPNLKNARSFVLDEVVPAGKGGAAA
>Mature_285_residues
MMFKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEANDIVVRKAARLAGELAIY
LHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDVDLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRF
PELFRQQAVAGAEIMSVPAAFTRQTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT
GEEIIIAEIDPLAVHTARAKIPNLKNARSFVLDEVVPAGKGGAAA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=38.8059701492537, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=38.8059701492537, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=38.8059701492537, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=34.8148148148148, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI297632346, Length=191, Percent_Identity=36.6492146596859, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786412, Length=241, Percent_Identity=26.5560165975104, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=271, Percent_Identity=38.0073800738007, Blast_Score=157, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6322335, Length=296, Percent_Identity=32.7702702702703, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323383, Length=210, Percent_Identity=38.5714285714286, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17933642, Length=266, Percent_Identity=37.593984962406, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355835, Length=195, Percent_Identity=35.3846153846154, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30655; Mature: 30655

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRD
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHC
EANDIVVRKAARLAGELAIYLHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDV
CCHHHHHHHHHHHHCEEEEEEEECCCCEEEECCCCCCCCEEECCCCCCEECCCCEEEEEE
DLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRFPELFRQQAVAGAEIMSVPAA
ECCCCCHHHHHCCCCCCCCEEEECCCCCHHCCEEEEECCCHHHHHHHHHCCHHHHHCCHH
FTRQTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT
HHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCCEEECHHHHHHHHCCCC
GEEIIIAEIDPLAVHTARAKIPNLKNARSFVLDEVVPAGKGGAAA
CCEEEEEECCCHHEEHHHHCCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMFKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRD
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHC
EANDIVVRKAARLAGELAIYLHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDV
CCHHHHHHHHHHHHCEEEEEEEECCCCEEEECCCCCCCCEEECCCCCCEECCCCEEEEEE
DLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRFPELFRQQAVAGAEIMSVPAA
ECCCCCHHHHHCCCCCCCCEEEECCCCCHHCCEEEEECCCHHHHHHHHHCCHHHHHCCHH
FTRQTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT
HHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCCEEECHHHHHHHHCCCC
GEEIIIAEIDPLAVHTARAKIPNLKNARSFVLDEVVPAGKGGAAA
CCEEEEEECCCHHEEHHHHCCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]