| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
Click here to switch to the map view.
The map label for this gene is gno [H]
Identifier: 150397676
GI number: 150397676
Start: 2558462
End: 2559181
Strand: Reverse
Name: gno [H]
Synonym: Smed_2476
Alternate gene names: 150397676
Gene position: 2559181-2558462 (Counterclockwise)
Preceding gene: 150397678
Following gene: 150397675
Centisome position: 67.67
GC content: 64.31
Gene sequence:
>720_bases GTGTATCTCGAACGCTTCAAGCTTGACGGCGAACTGGCAGTCGTCACCGGAGGAGGGCGCGGCATCGGACTTGCAAGCGC CGATGCGCTCGGCGAAGCCGGTGCGCGTCTTGCCCTTATCGAGCGCGATCCGGACCTCCTCGAGGAGGCACGCGCCGTCC TTCAGGACAAGGGCTACGACGTCTCGGTGCACGAGGGCGACGTTACCGACGCCGCGCGGATGCAGGCAATTGCGGACGAA CTGGCGGCGAAAGGCGGCGCCTCCATCCTCGTCAACAATGCCGGCATCGCGCTCAGTGATATCCCTGCCGAGAACATGGA GGACGAACGCTGGCTCAAGGTCATCGACGTCAACCTGAACGGGGTCTACTGGTGCAGCCGTGCTTTCGGCCGGCACATGC TGTCGATGGGCCGAGGCTCCATCGTCAATGTCGGCTCCATGTCCGGTTTCATCGTCAATCGGCCGCAGCCGCAGGCTCAT TACAACGCCTCGAAGGCAGCGGTCCATCAACTGACCCGCTCGCTCGCCGCTGAATGGGCGTCGCGCGGCGTACGGGTCAA CGCGGTCGCGCCCACCTACATCGAAACACCGCTCAACGCGCTGGTCGAGAACGACAGGCCGATGCTCGACCGCTGGCTCG ATTCAACGCCGATGGCGCGCATGGGCAAGGACCACGAGGTCGCAAGCGTGATCCTCTTCCTGTCCTCTCAGGCGGCATGA
Upstream 100 bases:
>100_bases CCGTACAACATAATAAGCGCAGACGCTGATATAGCATATCGCGCTGAGCTCTCAAACCGGGCTCAGGGCTGGGCCGACTG CGGCATGAACAGGGGGCAGA
Downstream 100 bases:
>100_bases CCGGATCGGTCGTACTCGTGGATGGAGGATACACGCTCTGGTGACCGTATCCCGCACCGGGTGCGCACTTCGTCGTGTTT TCCGAACCTAAGAAAAGCAG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 239; Mature: 239
Protein sequence:
>239_residues MYLERFKLDGELAVVTGGGRGIGLASADALGEAGARLALIERDPDLLEEARAVLQDKGYDVSVHEGDVTDAARMQAIADE LAAKGGASILVNNAGIALSDIPAENMEDERWLKVIDVNLNGVYWCSRAFGRHMLSMGRGSIVNVGSMSGFIVNRPQPQAH YNASKAAVHQLTRSLAAEWASRGVRVNAVAPTYIETPLNALVENDRPMLDRWLDSTPMARMGKDHEVASVILFLSSQAA
Sequences:
>Translated_239_residues MYLERFKLDGELAVVTGGGRGIGLASADALGEAGARLALIERDPDLLEEARAVLQDKGYDVSVHEGDVTDAARMQAIADE LAAKGGASILVNNAGIALSDIPAENMEDERWLKVIDVNLNGVYWCSRAFGRHMLSMGRGSIVNVGSMSGFIVNRPQPQAH YNASKAAVHQLTRSLAAEWASRGVRVNAVAPTYIETPLNALVENDRPMLDRWLDSTPMARMGKDHEVASVILFLSSQAA >Mature_239_residues MYLERFKLDGELAVVTGGGRGIGLASADALGEAGARLALIERDPDLLEEARAVLQDKGYDVSVHEGDVTDAARMQAIADE LAAKGGASILVNNAGIALSDIPAENMEDERWLKVIDVNLNGVYWCSRAFGRHMLSMGRGSIVNVGSMSGFIVNRPQPQAH YNASKAAVHQLTRSLAAEWASRGVRVNAVAPTYIETPLNALVENDRPMLDRWLDSTPMARMGKDHEVASVILFLSSQAA
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=239, Percent_Identity=32.2175732217573, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=32.7800829875519, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=31.8548387096774, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI40254992, Length=225, Percent_Identity=33.7777777777778, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI5031737, Length=232, Percent_Identity=29.7413793103448, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI10190704, Length=236, Percent_Identity=30.5084745762712, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=31.0924369747899, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI126723750, Length=242, Percent_Identity=28.5123966942149, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=33.1578947368421, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=32.1608040201005, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=30.9644670050761, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI7705855, Length=212, Percent_Identity=30.188679245283, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI31542939, Length=211, Percent_Identity=30.3317535545024, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI226371731, Length=230, Percent_Identity=27.8260869565217, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4557649, Length=200, Percent_Identity=29.5, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI4758504, Length=238, Percent_Identity=30.672268907563, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI66933014, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=31.8407960199005, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=35.1694915254237, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=33.6134453781513, Blast_Score=107, Evalue=6e-25, Organism=Escherichia coli, GI2367175, Length=240, Percent_Identity=35.4166666666667, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082100, Length=237, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=32.0987654320988, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=29.3388429752066, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1788459, Length=236, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=29.5081967213115, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=31.1203319502075, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI1786812, Length=238, Percent_Identity=31.0924369747899, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=30.2197802197802, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=29.957805907173, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17555706, Length=231, Percent_Identity=35.9307359307359, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI25147288, Length=238, Percent_Identity=37.3949579831933, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17560676, Length=236, Percent_Identity=30.0847457627119, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562904, Length=246, Percent_Identity=30.8943089430894, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560150, Length=244, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=251, Percent_Identity=29.4820717131474, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI193204405, Length=245, Percent_Identity=31.0204081632653, Blast_Score=95, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994600, Length=238, Percent_Identity=32.3529411764706, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=29.0983606557377, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562990, Length=244, Percent_Identity=29.9180327868852, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17562906, Length=246, Percent_Identity=28.4552845528455, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17559104, Length=240, Percent_Identity=29.5833333333333, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560332, Length=249, Percent_Identity=28.9156626506024, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560220, Length=243, Percent_Identity=27.5720164609054, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994604, Length=235, Percent_Identity=32.7659574468085, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562908, Length=249, Percent_Identity=30.1204819277108, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561402, Length=237, Percent_Identity=27.4261603375527, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17565030, Length=249, Percent_Identity=29.718875502008, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17538480, Length=247, Percent_Identity=29.1497975708502, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI72000259, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17538182, Length=241, Percent_Identity=29.8755186721992, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538486, Length=243, Percent_Identity=27.9835390946502, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536651, Length=243, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17551412, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17536025, Length=241, Percent_Identity=31.5352697095436, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=28.9855072463768, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI115534694, Length=231, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=29.7979797979798, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=241, Percent_Identity=33.195020746888, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17563726, Length=250, Percent_Identity=27.6, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17564282, Length=221, Percent_Identity=28.9592760180996, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17567345, Length=209, Percent_Identity=29.1866028708134, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=28.9099526066351, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=30.8510638297872, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=30.8943089430894, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=238, Percent_Identity=24.7899159663866, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI23397609, Length=238, Percent_Identity=37.8151260504202, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24639444, Length=238, Percent_Identity=33.1932773109244, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI21357041, Length=237, Percent_Identity=33.7552742616034, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644339, Length=240, Percent_Identity=34.1666666666667, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI28571526, Length=236, Percent_Identity=33.4745762711864, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI21355319, Length=235, Percent_Identity=31.063829787234, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=239, Percent_Identity=32.2175732217573, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=229, Percent_Identity=31.0043668122271, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI116007236, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24584752, Length=202, Percent_Identity=33.1683168316832, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=30.6532663316583, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=32.0388349514563, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007238, Length=206, Percent_Identity=29.6116504854369, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI17737361, Length=244, Percent_Identity=31.5573770491803, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28574402, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24584744, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24641388, Length=213, Percent_Identity=30.9859154929577, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24648693, Length=206, Percent_Identity=29.126213592233, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI21355889, Length=206, Percent_Identity=29.126213592233, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI24581726, Length=202, Percent_Identity=27.2277227722772, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 25698; Mature: 25698
Theoretical pI: Translated: 4.96; Mature: 4.96
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLERFKLDGELAVVTGGGRGIGLASADALGEAGARLALIERDPDLLEEARAVLQDKGYD CCCHHEECCCCEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCE VSVHEGDVTDAARMQAIADELAAKGGASILVNNAGIALSDIPAENMEDERWLKVIDVNLN EEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCEEEEEEECCC GVYWCSRAFGRHMLSMGRGSIVNVGSMSGFIVNRPQPQAHYNASKAAVHQLTRSLAAEWA CEEEHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHCCHHHHHHHHHHHHHHHHHH SRGVRVNAVAPTYIETPLNALVENDRPMLDRWLDSTPMARMGKDHEVASVILFLSSQAA HCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCC >Mature Secondary Structure MYLERFKLDGELAVVTGGGRGIGLASADALGEAGARLALIERDPDLLEEARAVLQDKGYD CCCHHEECCCCEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCE VSVHEGDVTDAARMQAIADELAAKGGASILVNNAGIALSDIPAENMEDERWLKVIDVNLN EEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCEEEEEEECCC GVYWCSRAFGRHMLSMGRGSIVNVGSMSGFIVNRPQPQAHYNASKAAVHQLTRSLAAEWA CEEEHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHCCHHHHHHHHHHHHHHHHHH SRGVRVNAVAPTYIETPLNALVENDRPMLDRWLDSTPMARMGKDHEVASVILFLSSQAA HCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]