Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 150397592

GI number: 150397592

Start: 2468208

End: 2469326

Strand: Reverse

Name: livK [C]

Synonym: Smed_2392

Alternate gene names: 150397592

Gene position: 2469326-2468208 (Counterclockwise)

Preceding gene: 150397593

Following gene: 150397590

Centisome position: 65.29

GC content: 60.23

Gene sequence:

>1119_bases
ATGAGAAAGTCTCTTCTGTCGGCCGTTGCGCTGACAGCAATGCTCGCCTTCAGCGGCACCGCATGGGCTGAGATCCTGGT
CGGCGTCGGAGCTCCGCTAACCGGTCCGAACGCCGCATTCGGCGCGCAGATTCAGAAAGGTGCAGAGCAGGCCGCCGAAG
ACATCAATGCTGCAGGCGGCATCAATGGGGAACAGATCAGGATTGTGCTGGGCGATGACGTTTCGGACCCTAAACAGGGT
GTTTCCGTTGCCCAGAAATTCGTCGCCGACGGCGTGAAGTTTGTCGTTGGTCACTTCAACTCGGGTGTGTCGATCCCTGC
ATCGGAAATCTACGCCGAAAACGGCCTCCTGCAGGTCACGCCTGCCTCGACCAACCCGCAGTTCACCGAACGCGGCCTGT
GGAATACCTTCCGCACCTGCGGCCGGGACGACCAGCAGGGCGCTGTTGCCGGCGCCTATATCGCGGCCAATTTCAAGGAT
GCGAAGGTCGCCGTCATTCACGACAAGACGCCCTATGGTCAGGGCCTTGCCGACGAAACCAAGAAGTCGATGAACGAAGC
CGGCGTCACCGAGGCCCTCTATGAAGGCATCAACACCGGCGACAAGGACTTCTCCGCCCTTATTGCCAAGATGAAGCAGG
CTGGCGTTTCGATCGTCTATTACGGCGGTCTGCACACGGAAGCCGGCCTGATCATGCGTCAGATGAAGGACCAGGGCCTG
AAGGCGACGCTGATGTCGGGCGACGGCATCGTCTCGAACGAACTGGCCTCGATCGCCGGCGACGCCGTTGACGGTACGCT
GATGACCTTCGCACCGGATCCGCGCAAGAGCCCGGCTGCCAAGGATCTCGTCGAGAAGTTCCGCACTGCGGGCTTTGAGC
CGGAAGCCTACACGCTCTATGCTTATGCGGCCCTTCAGGTCATTGCAGAAGGTGCCAAGGCTGCCGGCAATAGCGATCCG
CAGGCCGTCGCCGAAGCGATCAAGGCCAAAGGCCCGTTTAAGACCGCGATCGGCGAACTCGGCTTCGACGAAAAGGGCGA
CATCACCCGTCCGGACTACGTCATGTACACCTGGAAGAAGGGTGACGACGGCAAGTTCAGCTACTTCCAGAACGAATAG

Upstream 100 bases:

>100_bases
CCGGCCCGCGCGGCCGGTGCGAAAAAACACCGGCGCTATGATGGTGGGCATTGCGCAGGCTTATGAAACGAGACCCGCTC
GGATAATTGGGAGTAACAAG

Downstream 100 bases:

>100_bases
TTCTTTTCGAAGGTAATCCAGAAGGCCCGGCGCCAAGCGCCGGGCCTTCCATCGTTTTGGGCGCGCCGGGAGGACATGTC
CTCCCGGCGCCTGGTTAAAC

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRKSLLSAVALTAMLAFSGTAWAEILVGVGAPLTGPNAAFGAQIQKGAEQAAEDINAAGGINGEQIRIVLGDDVSDPKQG
VSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGLLQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKD
AKVAVIHDKTPYGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL
KATLMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRTAGFEPEAYTLYAYAALQVIAEGAKAAGNSDP
QAVAEAIKAKGPFKTAIGELGFDEKGDITRPDYVMYTWKKGDDGKFSYFQNE

Sequences:

>Translated_372_residues
MRKSLLSAVALTAMLAFSGTAWAEILVGVGAPLTGPNAAFGAQIQKGAEQAAEDINAAGGINGEQIRIVLGDDVSDPKQG
VSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGLLQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKD
AKVAVIHDKTPYGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL
KATLMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRTAGFEPEAYTLYAYAALQVIAEGAKAAGNSDP
QAVAEAIKAKGPFKTAIGELGFDEKGDITRPDYVMYTWKKGDDGKFSYFQNE
>Mature_372_residues
MRKSLLSAVALTAMLAFSGTAWAEILVGVGAPLTGPNAAFGAQIQKGAEQAAEDINAAGGINGEQIRIVLGDDVSDPKQG
VSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGLLQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKD
AKVAVIHDKTPYGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL
KATLMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRTAGFEPEAYTLYAYAALQVIAEGAKAAGNSDP
QAVAEAIKAKGPFKTAIGELGFDEKGDITRPDYVMYTWKKGDDGKFSYFQNE

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=360, Percent_Identity=39.7222222222222, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI48994941, Length=346, Percent_Identity=40.7514450867052, Blast_Score=259, Evalue=3e-70,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 39158; Mature: 39158

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSLLSAVALTAMLAFSGTAWAEILVGVGAPLTGPNAAFGAQIQKGAEQAAEDINAAGG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
INGEQIRIVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGLLQVT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCCCEEEEE
PASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADET
CCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHH
KKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCC
KATLMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRTAGFEPEAYTLY
EEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEHH
AYAALQVIAEGAKAAGNSDPQAVAEAIKAKGPFKTAIGELGFDEKGDITRPDYVMYTWKK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEC
GDDGKFSYFQNE
CCCCCCCCCCCC
>Mature Secondary Structure
MRKSLLSAVALTAMLAFSGTAWAEILVGVGAPLTGPNAAFGAQIQKGAEQAAEDINAAGG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
INGEQIRIVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGLLQVT
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHCCCEEEEE
PASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADET
CCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCHHHH
KKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCC
KATLMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRTAGFEPEAYTLY
EEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEHH
AYAALQVIAEGAKAAGNSDPQAVAEAIKAKGPFKTAIGELGFDEKGDITRPDYVMYTWKK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEEC
GDDGKFSYFQNE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA