| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
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The map label for this gene is polS [H]
Identifier: 150397554
GI number: 150397554
Start: 2429994
End: 2430767
Strand: Reverse
Name: polS [H]
Synonym: Smed_2354
Alternate gene names: 150397554
Gene position: 2430767-2429994 (Counterclockwise)
Preceding gene: 150397555
Following gene: 150397553
Centisome position: 64.27
GC content: 63.7
Gene sequence:
>774_bases ATGAAACGTCTCGAAGGCAAGAGTGCGCTGATCACCGGATCGGCCCGGGGAATTGGCCGCGCTTTCGCAGAGGCCTATGT GCGCGAGGGTGCCATGGTCGCGATCGCCGATATCAATATCGAGCGTGCAAGGCAGGCTGCGGCGGAAATCGGAGCGGCGG CCTATGCGGTCGAAATGGACGTGACCCGGCAGGACGCCATCGATGCGGCGATCGCGCAGACTGTCGGACATGCCGGTGGG CTCGATATCCTCGTCAACAATGCGGCGCTCTTCGATCTGGCTCCCATCGCGGACATAACCCGCGAGAGCTATGACAAGCT GTTCTCGATCAATGTCGCCGGAACGCTCTTCACGCTGCAGGCTGCCGCCAGGCAGATGATCGCGCAGGGCAGGGGTGGAA AGATCATCAACATGGCGAGCCAGGCCGGCCGGCGCGGGGAGGCTCTGGTGGCTATCTACTGCGCTACCAAGGCGGCAGTC ATCAGCCTCACGCAGTCGGCCGGACTGGATCTCATCAGGCACCGCATCAACGTCAATGCCATCGCTCCGGGGGTCGTCGA CGGCGAGCACTGGGAGGGCGTCGACGCGCTGTTCGCAAGGTATGAAAACCGTCCGCGCGGCGAGAAGAAGCGGCTGGTCG GCGAGGCCGTGCCCTACGGGCGCATGGGAACGGCGGAGGACCTGACCGGCATGGCGATCTTTCTCGCCTCGTCCGAAAGC GACTACGTTGTCGCTCAGACCTACAACGTCGACGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases GCGTCGGCGGCGATTTCGCCGTCACCCATGGCGACCAGGTTTTCCTGACACCGGATCCGCAGCATCTGCACAGGTTCGAC GAGAAGGGAATGGCAATTCG
Downstream 100 bases:
>100_bases GACGCGGGTTCTCGAAAGGAACAACAGGATGACGACCAAACTCTCGCTTGCCACGCTCGATGCGGTCAGGGCCAAGGCTG GCATTCCGAATTATGGCCGG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 257; Mature: 257
Protein sequence:
>257_residues MKRLEGKSALITGSARGIGRAFAEAYVREGAMVAIADINIERARQAAAEIGAAAYAVEMDVTRQDAIDAAIAQTVGHAGG LDILVNNAALFDLAPIADITRESYDKLFSINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAV ISLTQSAGLDLIRHRINVNAIAPGVVDGEHWEGVDALFARYENRPRGEKKRLVGEAVPYGRMGTAEDLTGMAIFLASSES DYVVAQTYNVDGGNWMS
Sequences:
>Translated_257_residues MKRLEGKSALITGSARGIGRAFAEAYVREGAMVAIADINIERARQAAAEIGAAAYAVEMDVTRQDAIDAAIAQTVGHAGG LDILVNNAALFDLAPIADITRESYDKLFSINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAV ISLTQSAGLDLIRHRINVNAIAPGVVDGEHWEGVDALFARYENRPRGEKKRLVGEAVPYGRMGTAEDLTGMAIFLASSES DYVVAQTYNVDGGNWMS >Mature_257_residues MKRLEGKSALITGSARGIGRAFAEAYVREGAMVAIADINIERARQAAAEIGAAAYAVEMDVTRQDAIDAAIAQTVGHAGG LDILVNNAALFDLAPIADITRESYDKLFSINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAV ISLTQSAGLDLIRHRINVNAIAPGVVDGEHWEGVDALFARYENRPRGEKKRLVGEAVPYGRMGTAEDLTGMAIFLASSES DYVVAQTYNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=30.5882352941176, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=35.7843137254902, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=29.3233082706767, Blast_Score=108, Evalue=7e-24, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=34.2412451361868, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=30.6201550387597, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=27.9352226720648, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=25.7692307692308, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=36.7816091954023, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=31.304347826087, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=27.734375, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=24.8908296943231, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI40807363, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI210032110, Length=163, Percent_Identity=28.2208588957055, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.2553191489362, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4758504, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=25.3393665158371, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=28.6324786324786, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=26.8421052631579, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=25, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=34.1176470588235, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=33.7254901960784, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=31.3253012048193, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=32.5396825396825, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=33.5849056603774, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.496062992126, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=30.6818181818182, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=32.4324324324324, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=30.5019305019305, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=29.296875, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=27.4509803921569, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=29.5275590551181, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=27.1276595744681, Blast_Score=66, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560150, Length=273, Percent_Identity=32.2344322344322, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=31.7164179104478, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=31.4814814814815, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=278, Percent_Identity=32.7338129496403, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=32, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=30.9701492537313, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=30.9090909090909, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=32.4817518248175, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=29.1828793774319, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=32.5925925925926, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=29.0441176470588, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=29.1187739463602, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=27.6752767527675, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=29.0196078431373, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=29.4776119402985, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=29.0909090909091, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=27.1739130434783, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=29.4776119402985, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=30.8823529411765, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.0588235294118, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17564282, Length=211, Percent_Identity=28.436018957346, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=29.2418772563177, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=30.5147058823529, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=25.968992248062, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=30.6201550387597, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=31.3131313131313, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=26.3959390862944, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17567345, Length=174, Percent_Identity=29.8850574712644, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=168, Percent_Identity=29.7619047619048, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=25.6, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71982365, Length=148, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=255, Percent_Identity=28.6274509803922, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=25.8687258687259, Blast_Score=76, Evalue=7e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=9e-14, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.4110671936759, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=29.9610894941634, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=26.9230769230769, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=28.740157480315, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI281364892, Length=190, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=32.1052631578947, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24640492, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=25.2475247524752, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI116007234, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24663911, Length=202, Percent_Identity=27.2277227722772, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=28.1368821292776, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24665243, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI221331218, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357673, Length=148, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27217; Mature: 27217
Theoretical pI: Translated: 5.78; Mature: 5.78
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRLEGKSALITGSARGIGRAFAEAYVREGAMVAIADINIERARQAAAEIGAAAYAVEMD CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCHHEEEEEEC VTRQDAIDAAIAQTVGHAGGLDILVNNAALFDLAPIADITRESYDKLFSINVAGTLFTLQ CCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHEEEEEEHHHHHHHH AAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIRHRINVNA HHHHHHHHCCCCCEEEEEHHHCCCCCCEEEEEEEECHHHEEEEHHHCCHHHHHHHHCCCE IAPGVVDGEHWEGVDALFARYENRPRGEKKRLVGEAVPYGRMGTAEDLTGMAIFLASSES ECCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC DYVVAQTYNVDGGNWMS CEEEEEEEECCCCCCCC >Mature Secondary Structure MKRLEGKSALITGSARGIGRAFAEAYVREGAMVAIADINIERARQAAAEIGAAAYAVEMD CCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCHHEEEEEEC VTRQDAIDAAIAQTVGHAGGLDILVNNAALFDLAPIADITRESYDKLFSINVAGTLFTLQ CCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHEEEEEEHHHHHHHH AAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIRHRINVNA HHHHHHHHCCCCCEEEEEHHHCCCCCCEEEEEEEECHHHEEEEHHHCCHHHHHHHHCCCE IAPGVVDGEHWEGVDALFARYENRPRGEKKRLVGEAVPYGRMGTAEDLTGMAIFLASSES ECCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCC DYVVAQTYNVDGGNWMS CEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]