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The map label for this gene is engD [H]

Identifier: 150397466

GI number: 150397466

Start: 2343331

End: 2344434

Strand: Direct

Name: engD [H]

Synonym: Smed_2266

Alternate gene names: 150397466

Gene position: 2343331-2344434 (Clockwise)

Preceding gene: 150397464

Following gene: 150397468

Centisome position: 61.96

GC content: 61.87

Gene sequence:

>1104_bases
ATGGGCTTCAAATGCGGTATCGTCGGGCTGCCGAATGTCGGCAAGTCCACCCTCTTCAACGCGCTGACCAAGACGGCGGC
GGCGCAGGCGGCCAATTATCCTTTCTGCACGATCGAGCCGAACACCGGCGAAGTCGCCGTGCCCGACCCGCGCATGCGCA
GGCTCGCAGACATTGCCAAATCGAAAGAGATCATTCCAACCCGCATCTCCTTCGTCGATATTGCCGGGCTGGTGCGCGGC
GCGTCCAAGGGTGAGGGCCTCGGCAACCAGTTCCTCGCCAACATACGCGAGGTGGATGCAGTCGTGCACGTATTGCGCTG
CTTCGAGGACGAAGACATCACCCATGTCGAGGGCCGTATCCATCCGGTCGAAGACGCCGACACGATTGAGACCGAGCTGA
TGCTCGCCGATCTGGAAAGCCTCGAACGGCGTGCAGACCAGACGCGCAAGCGCGCGACCGGCAAGGACAAGGAATCGATG
GCGCAGCTTCCGATCATGGAAGCTTCCCTGAAGCTGCTGCAGGAAGGCAAGCCCGTCCGCACCCTGCTCTCCAGGCTCGA
CGCCGATGAGCTGCGTATTCTGCAGAGTCTCAACCTGCTCACTTCGCACCCGGTTCTTTACGTCTGCAACGTCGCAGAAA
GCGACGCCGCGACCGGAAACGAGCACACCCGCGCCGTCGAAAAGATGGCCCAAGAGCAAGGCGCCGAGACGGTGATCATA
TCGGCTGCGATCGAGTCCGAAGTGGCGCAGCTGCCGGAAGAGGAAGCTCACGAATTTCTCGCGGCGCTCGGCCTCGAAGA
AGCGGGCCTCGATAGGCTGATCCGCGCCGGCTACAAGCTCCTCGATCTCATCACCTATTTCACCGTCGGTCCGAAGGAGA
CTCGCGCCTGGACCATCCCGCGCGGCACCAAGGCCCCGCAGGCCGCCGGTGTCATCCACTCGGACTTCGAGCGTGGTTTC
ATTCGCGCCAACACGATCGCCTATGACGATTACATCGCCTATGGCGGCGAAAACGGCGCGAAGGAAGCCGGCAAGGCGCG
GGATGAAGGCAAGGAATACGTCGTCCAGGACGGCGACGTCATCCATTTCCGGTTCAACACGTAA

Upstream 100 bases:

>100_bases
ACTCGCCATAAGGGGCAAGCGGAATACGCGAAAAGCTTGACCGCCCCTTTCCTTTATCCCATAGCCACGCCCAAGCAATC
AGGAACGACGGATTATAGCC

Downstream 100 bases:

>100_bases
GCGACAATCCGGATTCCAGACCGGCGGCGCTCACCGCACGGCATGCAGCCGCGCTGTGACCGCTTCCGGCAGCAGGCTCA
TTGCCGCCCGGCGCAGCGGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRRLADIAKSKEIIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAVVHVLRCFEDEDITHVEGRIHPVEDADTIETELMLADLESLERRADQTRKRATGKDKESM
AQLPIMEASLKLLQEGKPVRTLLSRLDADELRILQSLNLLTSHPVLYVCNVAESDAATGNEHTRAVEKMAQEQGAETVII
SAAIESEVAQLPEEEAHEFLAALGLEEAGLDRLIRAGYKLLDLITYFTVGPKETRAWTIPRGTKAPQAAGVIHSDFERGF
IRANTIAYDDYIAYGGENGAKEAGKARDEGKEYVVQDGDVIHFRFNT

Sequences:

>Translated_367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRRLADIAKSKEIIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAVVHVLRCFEDEDITHVEGRIHPVEDADTIETELMLADLESLERRADQTRKRATGKDKESM
AQLPIMEASLKLLQEGKPVRTLLSRLDADELRILQSLNLLTSHPVLYVCNVAESDAATGNEHTRAVEKMAQEQGAETVII
SAAIESEVAQLPEEEAHEFLAALGLEEAGLDRLIRAGYKLLDLITYFTVGPKETRAWTIPRGTKAPQAAGVIHSDFERGF
IRANTIAYDDYIAYGGENGAKEAGKARDEGKEYVVQDGDVIHFRFNT
>Mature_366_residues
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRRLADIAKSKEIIPTRISFVDIAGLVRGA
SKGEGLGNQFLANIREVDAVVHVLRCFEDEDITHVEGRIHPVEDADTIETELMLADLESLERRADQTRKRATGKDKESMA
QLPIMEASLKLLQEGKPVRTLLSRLDADELRILQSLNLLTSHPVLYVCNVAESDAATGNEHTRAVEKMAQEQGAETVIIS
AAIESEVAQLPEEEAHEFLAALGLEEAGLDRLIRAGYKLLDLITYFTVGPKETRAWTIPRGTKAPQAAGVIHSDFERGFI
RANTIAYDDYIAYGGENGAKEAGKARDEGKEYVVQDGDVIHFRFNT

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=43.7837837837838, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=38.9908256880734, Blast_Score=158, Evalue=7e-39,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=56.9482288828338, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=33.8461538461538, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=43.2065217391304, Blast_Score=293, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=40.8602150537634, Blast_Score=274, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=37.2031662269129, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6321649, Length=318, Percent_Identity=27.9874213836478, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.9354838709677, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.9354838709677, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.9354838709677, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24640879, Length=333, Percent_Identity=39.3393393393393, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI20129375, Length=171, Percent_Identity=28.6549707602339, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40159; Mature: 40028

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRRLADIAK
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKEIIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAVVHVLRCFEDEDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCE
HPVEDADTIETELMLADLESLERRADQTRKRATGKDKESMAQLPIMEASLKLLQEGKPVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCHHH
TLLSRLDADELRILQSLNLLTSHPVLYVCNVAESDAATGNEHTRAVEKMAQEQGAETVII
HHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIESEVAQLPEEEAHEFLAALGLEEAGLDRLIRAGYKLLDLITYFTVGPKETRAWTIP
EHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
RGTKAPQAAGVIHSDFERGFIRANTIAYDDYIAYGGENGAKEAGKARDEGKEYVVQDGDV
CCCCCCHHHCCHHHHHHCCCEEECEEEECCCEEECCCCCHHHHCCCHHCCCEEEEECCCE
IHFRFNT
EEEEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRMRRLADIAK
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKEIIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAVVHVLRCFEDEDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCE
HPVEDADTIETELMLADLESLERRADQTRKRATGKDKESMAQLPIMEASLKLLQEGKPVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCHHH
TLLSRLDADELRILQSLNLLTSHPVLYVCNVAESDAATGNEHTRAVEKMAQEQGAETVII
HHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIESEVAQLPEEEAHEFLAALGLEEAGLDRLIRAGYKLLDLITYFTVGPKETRAWTIP
EHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
RGTKAPQAAGVIHSDFERGFIRANTIAYDDYIAYGGENGAKEAGKARDEGKEYVVQDGDV
CCCCCCHHHCCHHHHHHCCCEEECEEEECCCEEECCCCCHHHHCCCHHCCCEEEEECCCE
IHFRFNT
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA