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The map label for this gene is aatA [H]

Identifier: 150397433

GI number: 150397433

Start: 2313662

End: 2314864

Strand: Reverse

Name: aatA [H]

Synonym: Smed_2233

Alternate gene names: 150397433

Gene position: 2314864-2313662 (Counterclockwise)

Preceding gene: 150397440

Following gene: 150397430

Centisome position: 61.21

GC content: 62.76

Gene sequence:

>1203_bases
ATGGCCTTCCTTGCCGATGCCCTTTCCCGTGTAAAGCCTTCCGCCACTATCGCCGTTTCGCAGAAAGCCCGCGAGTTGAA
AGCGAAAGGCCGCGACGTCATCGGCCTCGGCGCGGGAGAGCCGGATTTCGACACGCCTGATAATATCAAGGCGGCTGCGA
TCGATGCGATCAATCGCGGCGAGACGAAATACACGCCGGTCTCCGGCATTCCCGAACTGCGCGAAGCCATCGCCAGGAAG
TTCAAGCGCGAGAACAATCTCGAATACACGGCGGCGCAGACGATCGTCGGCACCGGCGGAAAGCAGATTCTCTTCAACGC
CTTCATGGCCACGCTCAATCCGGGCGATGAAGTCGTGATCCCCGCACCCTACTGGGTGTCCTATCCGGAAATGGTGGCGC
TATGCGGCGGTACGCCGGTTTTCGTCTCGACCGAGCAGGAGAACAACTTCAAGCTCAAGGCCGAGGATCTCGACCGGGCG
ATCACGCCGAAGACCAAGTGGTTCGTCTTCAACTCGCCGTCCAACCCCTCGGGCGCGGCCTATTCGCATGAGGAGCTCAA
GGCTCTGACGGACGTGCTCATGAAGCATCCGCATGTCTGGGTGCTGACCGACGACATGTACGAGCACCTGACCTATGGCG
ACTTCAAATTCGCGACCCCCGTCGAAGTCGAGCCCGGTCTATACGAGCGCACGCTGACGATGAACGGCGTCTCCAAGGCC
TATGCCATGACCGGCTGGCGCATCGGTTATGCGGCCGGTCCGCTTCAGCTCATCAAGGCGATGGACATGATCCAGGGCCA
GCAGACCTCGGGCGCGGCCTCGATCGCGCAGTGGGCTGCCGTCGAGGCGTTGAACGGTCCGCAGGACTTCATCGGGCGCA
ACAAGGAGATCTTTCAGGGCCGCCGCGACCTCGTGGTGTCGATGCTGAACCAGGCCAGGGGCATTTCCTGCCCGACTCCG
GAAGGCGCCTTCTACGTCTATCCGTCCTGCGCCGGGCTGATCGGCAAGACCGCGCCCTCGGGCAAGGTCCTTGAGACGGA
CGAGGACTTCGTCTCCGAGCTCCTCGAGACGGAAGGCGTCGCGGTGGTCCACGGCTCTGCCTTCGGCCTCGGCCCGAATT
TCCGCATCTCCTACGCGACCTCCGAGGCGCTGCTGGAGGAGGCCTGCCGCCGTATCCAGCGTTTCTGCGCCGCCTGCAGA
TAG

Upstream 100 bases:

>100_bases
AAGGACTGGCGTCTTTCGACATAGACCTAACCGCTATGGAGCCTCGTTTTTCCGTTCCGTAGCGTCTCACGCCGTTATCG
AAACGATCAGGAAACACACC

Downstream 100 bases:

>100_bases
CCTCCTCACGACTTCTGAACATGAAAAAGCCCGCCATCGGCGGGCTTTTTCATGTTCAGAACTTGATTCAGCGATCTCCG
GATACGGTTCAATCAGCAAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKAAAIDAINRGETKYTPVSGIPELREAIARK
FKRENNLEYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVSTEQENNFKLKAEDLDRA
ITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFKFATPVEVEPGLYERTLTMNGVSKA
YAMTGWRIGYAAGPLQLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQGRRDLVVSMLNQARGISCPTP
EGAFYVYPSCAGLIGKTAPSGKVLETDEDFVSELLETEGVAVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR

Sequences:

>Translated_400_residues
MAFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKAAAIDAINRGETKYTPVSGIPELREAIARK
FKRENNLEYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVSTEQENNFKLKAEDLDRA
ITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFKFATPVEVEPGLYERTLTMNGVSKA
YAMTGWRIGYAAGPLQLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQGRRDLVVSMLNQARGISCPTP
EGAFYVYPSCAGLIGKTAPSGKVLETDEDFVSELLETEGVAVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR
>Mature_399_residues
AFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKAAAIDAINRGETKYTPVSGIPELREAIARKF
KRENNLEYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVSTEQENNFKLKAEDLDRAI
TPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFKFATPVEVEPGLYERTLTMNGVSKAY
AMTGWRIGYAAGPLQLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQGRRDLVVSMLNQARGISCPTPE
GAFYVYPSCAGLIGKTAPSGKVLETDEDFVSELLETEGVAVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=358, Percent_Identity=26.8156424581006, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI56713256, Length=358, Percent_Identity=26.8156424581006, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=26.8844221105528, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=26.8844221105528, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=23.3502538071066, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=25.1295336787565, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=27.6139410187668, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=27.2264631043257, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=28.4210526315789, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=365, Percent_Identity=27.6712328767123, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=365, Percent_Identity=27.6712328767123, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=27.7777777777778, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=24.0837696335079, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=369, Percent_Identity=21.9512195121951, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=26.9035532994924, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320317, Length=363, Percent_Identity=22.5895316804408, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=22.1917808219178, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573069, Length=364, Percent_Identity=25.2747252747253, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=364, Percent_Identity=25.2747252747253, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=364, Percent_Identity=25.2747252747253, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=364, Percent_Identity=25.2747252747253, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=23.1382978723404, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24641770, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641760, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641768, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641766, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641764, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45551451, Length=370, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43521; Mature: 43390

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKAAAIDAINRG
CCHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCC
ETKYTPVSGIPELREAIARKFKRENNLEYTAAQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPEMVALCGGTPVFVSTEQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHCCCCCCCEEEEEEECCCCCCCCC
YSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFKFATPVEVEPGLYERTLTMNGVSKA
CCHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCCHHH
YAMTGWRIGYAAGPLQLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQG
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
RRDLVVSMLNQARGISCPTPEGAFYVYPSCAGLIGKTAPSGKVLETDEDFVSELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR
EEEECCEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFLADALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKAAAIDAINRG
CHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHCCC
ETKYTPVSGIPELREAIARKFKRENNLEYTAAQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPEMVALCGGTPVFVSTEQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAA
CCCCCCCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHCCCCCCCEEEEEEECCCCCCCCC
YSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFKFATPVEVEPGLYERTLTMNGVSKA
CCHHHHHHHHHHHHHCCCEEEEECHHHHHCCCCCEEECCCCCCCCCCCEEEEECCCCHHH
YAMTGWRIGYAAGPLQLIKAMDMIQGQQTSGAASIAQWAAVEALNGPQDFIGRNKEIFQG
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHH
RRDLVVSMLNQARGISCPTPEGAFYVYPSCAGLIGKTAPSGKVLETDEDFVSELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHCCCCCCCCEEECCHHHHHHHHHCCCE
AVVHGSAFGLGPNFRISYATSEALLEEACRRIQRFCAACR
EEEECCEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]