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The map label for this gene is idhA [H]

Identifier: 150397239

GI number: 150397239

Start: 2089642

End: 2090751

Strand: Reverse

Name: idhA [H]

Synonym: Smed_2038

Alternate gene names: 150397239

Gene position: 2090751-2089642 (Counterclockwise)

Preceding gene: 150397245

Following gene: 150397235

Centisome position: 55.28

GC content: 60.72

Gene sequence:

>1110_bases
ATGAGCAAACCGGACGAGAGCGACTATGCGCTCGAAACGGCGGAAGTGCCCCTCGTCGACGCACCCGTCCTGAATTACCG
ACCGCCGAGAACCAGGTCCTACGCGCCGGGCATTGCCGTCGTAGGTGCCGGGGGCATCTCCTTCGCCCATCTGGACGCCT
ATCGGAGCGCCGGATACGACGTGAGGGTGATCTGCAACCGCACGCTCTCCAAGGCGATCGAGCGTCGCGACGCGTTTTTC
CCGTCTGCCGATATTTCGGATGACTTTGACAGCGTCATCAGACGCGACGATATCGATGTCGTCGATATCACGACGCACCC
CATCGCGCGGGCGCCCATGATCGAAAGCGCGCTTCGCGCAGGCAAGCACGTGCTGTCCCAGAAACCATTCGTCCTCGACC
TCGATGCAGGGCTGCGGCTAGTGGAGATCGCCGAGCAGCAGGGGTTAAAGCTCGCCGTCAATCAGAATGGGCGCTGGGCA
CCGCATCTCGGCTACATGCGCGAAGCCGTCACAAGCGGTGTGATCGGGGACCTCATGTCCTGCCATATCGGCGTACATTG
GAACCATGGCTGGATCAGGGGCACGCCTTTCGAGAATATCGATGACCTCGTGTTTCAGGACTTCGCCATTCATTGGTTCG
ATTTCCTCGCAAGCGTGATTGGAAACCGCGCCACGTCAGTGATCGCTACCCGCACGCGTGCGTCGGGCCAGAGCGTCGCC
CCGCCGCTTCTGGCACAAGCCCTCGTGCAATTCGAAGGAGGGCAGGCCTCGCTCGTTTTCGACGGATCCGTTCCATATGG
TCCCTTGGACCGAACTTATATAGCGGGGACGAAGGGTAGCCTGTCCAGCTGGGGACCAAATCTCGGCCGGCAGAGTGTCG
AACTTTCAACCGAGAACGGCATTGCTCGGCCCGTTCTTTCCGGAACCTGGTTCAACGACGGATTCCGGGGTGCAATGGGC
GAATTATTGTGCGCGATCGAGGATGGTCGGGAGCCCCTTCACAATGCCCGAGCCAATCTCGATGGCCTTGCTTTGACGTT
TGCCGCAATTGCATCATGCCGTCGCCTGCAACCGGTAACCCCGTGGGGCGCCCGCACGGTGACGATCTGA

Upstream 100 bases:

>100_bases
GGACGTGCGCGATGGCAAAATGGCCTATCGCCGGAGGCCAGCAGATCATCGACAGCGCCGTTCTCTCCGCCCGGGAAAGG
CGCACCGTGGAGCTCCTACC

Downstream 100 bases:

>100_bases
TCGAGATCCGTTTCGTTTAGTGGGATTACGCCATCGAGGGGGTGCGGAGCCCATCCGAAGCACAAACTTCGTTCACCAGC
GCTCCGGCAGGAAGGCTCCA

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI-dehydrogenase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSKPDESDYALETAEVPLVDAPVLNYRPPRTRSYAPGIAVVGAGGISFAHLDAYRSAGYDVRVICNRTLSKAIERRDAFF
PSADISDDFDSVIRRDDIDVVDITTHPIARAPMIESALRAGKHVLSQKPFVLDLDAGLRLVEIAEQQGLKLAVNQNGRWA
PHLGYMREAVTSGVIGDLMSCHIGVHWNHGWIRGTPFENIDDLVFQDFAIHWFDFLASVIGNRATSVIATRTRASGQSVA
PPLLAQALVQFEGGQASLVFDGSVPYGPLDRTYIAGTKGSLSSWGPNLGRQSVELSTENGIARPVLSGTWFNDGFRGAMG
ELLCAIEDGREPLHNARANLDGLALTFAAIASCRRLQPVTPWGARTVTI

Sequences:

>Translated_369_residues
MSKPDESDYALETAEVPLVDAPVLNYRPPRTRSYAPGIAVVGAGGISFAHLDAYRSAGYDVRVICNRTLSKAIERRDAFF
PSADISDDFDSVIRRDDIDVVDITTHPIARAPMIESALRAGKHVLSQKPFVLDLDAGLRLVEIAEQQGLKLAVNQNGRWA
PHLGYMREAVTSGVIGDLMSCHIGVHWNHGWIRGTPFENIDDLVFQDFAIHWFDFLASVIGNRATSVIATRTRASGQSVA
PPLLAQALVQFEGGQASLVFDGSVPYGPLDRTYIAGTKGSLSSWGPNLGRQSVELSTENGIARPVLSGTWFNDGFRGAMG
ELLCAIEDGREPLHNARANLDGLALTFAAIASCRRLQPVTPWGARTVTI
>Mature_368_residues
SKPDESDYALETAEVPLVDAPVLNYRPPRTRSYAPGIAVVGAGGISFAHLDAYRSAGYDVRVICNRTLSKAIERRDAFFP
SADISDDFDSVIRRDDIDVVDITTHPIARAPMIESALRAGKHVLSQKPFVLDLDAGLRLVEIAEQQGLKLAVNQNGRWAP
HLGYMREAVTSGVIGDLMSCHIGVHWNHGWIRGTPFENIDDLVFQDFAIHWFDFLASVIGNRATSVIATRTRASGQSVAP
PLLAQALVQFEGGQASLVFDGSVPYGPLDRTYIAGTKGSLSSWGPNLGRQSVELSTENGIARPVLSGTWFNDGFRGAMGE
LLCAIEDGREPLHNARANLDGLALTFAAIASCRRLQPVTPWGARTVTI

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 40021; Mature: 39889

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPDESDYALETAEVPLVDAPVLNYRPPRTRSYAPGIAVVGAGGISFAHLDAYRSAGYD
CCCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCE
VRVICNRTLSKAIERRDAFFPSADISDDFDSVIRRDDIDVVDITTHPIARAPMIESALRA
EEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
GKHVLSQKPFVLDLDAGLRLVEIAEQQGLKLAVNQNGRWAPHLGYMREAVTSGVIGDLMS
HHHHHCCCCEEEECCCCCEEEHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
CHIGVHWNHGWIRGTPFENIDDLVFQDFAIHWFDFLASVIGNRATSVIATRTRASGQSVA
HEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCC
PPLLAQALVQFEGGQASLVFDGSVPYGPLDRTYIAGTKGSLSSWGPNLGRQSVELSTENG
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHCCCCCCCCEEEEECCCC
IARPVLSGTWFNDGFRGAMGELLCAIEDGREPLHNARANLDGLALTFAAIASCRRLQPVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
PWGARTVTI
CCCCEEECC
>Mature Secondary Structure 
SKPDESDYALETAEVPLVDAPVLNYRPPRTRSYAPGIAVVGAGGISFAHLDAYRSAGYD
CCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCE
VRVICNRTLSKAIERRDAFFPSADISDDFDSVIRRDDIDVVDITTHPIARAPMIESALRA
EEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
GKHVLSQKPFVLDLDAGLRLVEIAEQQGLKLAVNQNGRWAPHLGYMREAVTSGVIGDLMS
HHHHHCCCCEEEECCCCCEEEHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
CHIGVHWNHGWIRGTPFENIDDLVFQDFAIHWFDFLASVIGNRATSVIATRTRASGQSVA
HEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCC
PPLLAQALVQFEGGQASLVFDGSVPYGPLDRTYIAGTKGSLSSWGPNLGRQSVELSTENG
CHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCCCCHHCCCCCCCCEEEEECCCC
IARPVLSGTWFNDGFRGAMGELLCAIEDGREPLHNARANLDGLALTFAAIASCRRLQPVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
PWGARTVTI
CCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9802033; 11481431 [H]