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The map label for this gene is frpC [H]

Identifier: 150396999

GI number: 150396999

Start: 1878987

End: 1880600

Strand: Reverse

Name: frpC [H]

Synonym: Smed_1796

Alternate gene names: 150396999

Gene position: 1880600-1878987 (Counterclockwise)

Preceding gene: 150397001

Following gene: 150396998

Centisome position: 49.73

GC content: 59.98

Gene sequence:

>1614_bases
ATGACCACAGTAGTGGGCACGGCCGGAGTCGATATACTGGTTGGAACAGAGGAGAAGGACCGCATTTGGGGCCTTGCAGG
CGCGGATGATATCGAGGCCGGTGGCGGCGACGATCTCGTCGACGGTGGCGCCGGGGACGATCGTCTGGCAAGTACGAGCG
GATACGACCGCCTCGACGGCGGCGAGGGGGATGATCAAATAACCCTGATCGGTACCGGCGGCGCGGTTACGGGCGGGGCC
GGTACCGATACGTTGGTGATCGACCTTGCGAACGTCAGCACTTCCGTCCGGTTCAGCGGCGAGCACGGTCACGGCATCAT
CGGCTACAACACGTCAGACTGGGAGCATATATTCTTCAACCGCATCGAAAGGCTAGTGCTGACCACCGGCAGCGGCAATG
ACCGAATATTCGGCGCCTCGACTGATGATATCATCTCGACCGGTGGTGGTAACGACATTGTCGGGCCGTATGGCACCGAC
GGCGATGACGGCACAAGCATGCAGGGCGACGACACGATCAACACTGGCACCGGGGGCGACATCATCAATGACACTGTTGG
CTCGAACCGGATTTTTGCCGGTGACCATGACGACATCATCTTTACGACGCTTTCTTCCACGGTGATCGACGGCGGGACCG
GCTGGGACAGACTCACCCTGCTCGATGAAGAAAGAACCGGGGACGTGACCCTCGATTTTGCGCGGGGATTCGCCTCGACG
GGTACTCTGATCAACGGCATCGAGGTCGCCAACATCAATCTCGGTAATGGCAGCGACACGCTGATCGCCGGCAATCTCCT
TTCGCTCAGCGCTCATCTGGGCGAAGGTGACAATTACGCAGCCGGCAGCAGCGGCAGGGATTACATCGCTTCCGGGAGCG
GAGACGATGCCCTCTATGGCGACAGTGGCGACGACATCCTGATCAGCAACGGCGGTAATGACGTGCTCGTCGGGGGCGAT
GGGAACGACGAGATTCATGACTCGGGATCGCGCTTCGATGACGGTGACACGTATATTGACGGCGGCTCCGGCGACGATCT
CATCCAGATGGTTGCGCCCTCCGGCTTCATCGATGGCGGCGCCGGCAGCGATACATTGCGCGTCGTCGGCCCTCTGACGG
GCACACATTTCGATGCCTCGACGGGCATGCTGGGCACATCTCTTGTCTTTACCAATATCGAGAGGTTCGAACTTTCCGGC
GACTCAGGGGACGATACAATCCGCACGCTTGGAGGCGACGATCAGCTCGCCGGCAATGAGGGTAACGACCGGCTCGACGG
AGGAGCCGGCAAGGATGTGCTCTGGGGCGGGGGCGGTGACGATGTGATGACGGGCGGCGCCGGTGCCGATACCTACCTCT
GGTCTTCGGACACGTTTTCGTTCTCGGGTGTCGACCGCATTACCGATTTCGATTTCGACGGCGGGGATGTGCTGCGCTTT
ATCGGCAATGCATCGGATTCGACACGAATCGAGAGCTTCGCCGATCTGGTTGCTGCTGCGACCGAGACGGACGACGGGCT
CTATATCGCCTTCAACGGGTCCGACAATTTCGGACTGTTCCTGGACAACGTTGCGCTTCAAGACCTTTCCGCGGACGATA
TCGTTTTTGTCTGA

Upstream 100 bases:

>100_bases
TAATGTATATTATCACCAGTATTTATTTTTGATTGCATCTCGATTTTTTCTTTAAGCAATAATATTAATCTCATGCTTCG
CATTCAGGGGGAAGAGCGAC

Downstream 100 bases:

>100_bases
GAGCCCGAGCAGCTTCTTGAATCGCTGATTGGTACACAACGGCCGCTTTTCGGCGGCCGGGGTGTGCAATCCATCCGCGG
TTTGTGTCGATATCGGCGCT

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTTVVGTAGVDILVGTEEKDRIWGLAGADDIEAGGGDDLVDGGAGDDRLASTSGYDRLDGGEGDDQITLIGTGGAVTGGA
GTDTLVIDLANVSTSVRFSGEHGHGIIGYNTSDWEHIFFNRIERLVLTTGSGNDRIFGASTDDIISTGGGNDIVGPYGTD
GDDGTSMQGDDTINTGTGGDIINDTVGSNRIFAGDHDDIIFTTLSSTVIDGGTGWDRLTLLDEERTGDVTLDFARGFAST
GTLINGIEVANINLGNGSDTLIAGNLLSLSAHLGEGDNYAAGSSGRDYIASGSGDDALYGDSGDDILISNGGNDVLVGGD
GNDEIHDSGSRFDDGDTYIDGGSGDDLIQMVAPSGFIDGGAGSDTLRVVGPLTGTHFDASTGMLGTSLVFTNIERFELSG
DSGDDTIRTLGGDDQLAGNEGNDRLDGGAGKDVLWGGGGDDVMTGGAGADTYLWSSDTFSFSGVDRITDFDFDGGDVLRF
IGNASDSTRIESFADLVAAATETDDGLYIAFNGSDNFGLFLDNVALQDLSADDIVFV

Sequences:

>Translated_537_residues
MTTVVGTAGVDILVGTEEKDRIWGLAGADDIEAGGGDDLVDGGAGDDRLASTSGYDRLDGGEGDDQITLIGTGGAVTGGA
GTDTLVIDLANVSTSVRFSGEHGHGIIGYNTSDWEHIFFNRIERLVLTTGSGNDRIFGASTDDIISTGGGNDIVGPYGTD
GDDGTSMQGDDTINTGTGGDIINDTVGSNRIFAGDHDDIIFTTLSSTVIDGGTGWDRLTLLDEERTGDVTLDFARGFAST
GTLINGIEVANINLGNGSDTLIAGNLLSLSAHLGEGDNYAAGSSGRDYIASGSGDDALYGDSGDDILISNGGNDVLVGGD
GNDEIHDSGSRFDDGDTYIDGGSGDDLIQMVAPSGFIDGGAGSDTLRVVGPLTGTHFDASTGMLGTSLVFTNIERFELSG
DSGDDTIRTLGGDDQLAGNEGNDRLDGGAGKDVLWGGGGDDVMTGGAGADTYLWSSDTFSFSGVDRITDFDFDGGDVLRF
IGNASDSTRIESFADLVAAATETDDGLYIAFNGSDNFGLFLDNVALQDLSADDIVFV
>Mature_536_residues
TTVVGTAGVDILVGTEEKDRIWGLAGADDIEAGGGDDLVDGGAGDDRLASTSGYDRLDGGEGDDQITLIGTGGAVTGGAG
TDTLVIDLANVSTSVRFSGEHGHGIIGYNTSDWEHIFFNRIERLVLTTGSGNDRIFGASTDDIISTGGGNDIVGPYGTDG
DDGTSMQGDDTINTGTGGDIINDTVGSNRIFAGDHDDIIFTTLSSTVIDGGTGWDRLTLLDEERTGDVTLDFARGFASTG
TLINGIEVANINLGNGSDTLIAGNLLSLSAHLGEGDNYAAGSSGRDYIASGSGDDALYGDSGDDILISNGGNDVLVGGDG
NDEIHDSGSRFDDGDTYIDGGSGDDLIQMVAPSGFIDGGAGSDTLRVVGPLTGTHFDASTGMLGTSLVFTNIERFELSGD
SGDDTIRTLGGDDQLAGNEGNDRLDGGAGKDVLWGGGGDDVMTGGAGADTYLWSSDTFSFSGVDRITDFDFDGGDVLRFI
GNASDSTRIESFADLVAAATETDDGLYIAFNGSDNFGLFLDNVALQDLSADDIVFV

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 54872; Mature: 54741

Theoretical pI: Translated: 3.56; Mature: 3.56

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVVGTAGVDILVGTEEKDRIWGLAGADDIEAGGGDDLVDGGAGDDRLASTSGYDRLDG
CCEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEGDDQITLIGTGGAVTGGAGTDTLVIDLANVSTSVRFSGEHGHGIIGYNTSDWEHIFFN
CCCCCEEEEEECCCEEECCCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCHHHHHHH
RIERLVLTTGSGNDRIFGASTDDIISTGGGNDIVGPYGTDGDDGTSMQGDDTINTGTGGD
HEEEEEEEECCCCCEEEECCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IINDTVGSNRIFAGDHDDIIFTTLSSTVIDGGTGWDRLTLLDEERTGDVTLDFARGFAST
CCCCCCCCCEEEECCCCCEEEEEECCEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCC
GTLINGIEVANINLGNGSDTLIAGNLLSLSAHLGEGDNYAAGSSGRDYIASGSGDDALYG
CCEECCEEEEEEECCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEC
DSGDDILISNGGNDVLVGGDGNDEIHDSGSRFDDGDTYIDGGSGDDLIQMVAPSGFIDGG
CCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCC
AGSDTLRVVGPLTGTHFDASTGMLGTSLVFTNIERFELSGDSGDDTIRTLGGDDQLAGNE
CCCCEEEEEECCCCCCCCCCCCCCEEEEEEECEEEEEECCCCCCCEEEECCCCCCCCCCC
GNDRLDGGAGKDVLWGGGGDDVMTGGAGADTYLWSSDTFSFSGVDRITDFDFDGGDVLRF
CCCCCCCCCCCCEEECCCCCCEEECCCCCCCEEECCCCEEECCCCCCEECCCCCCHHHHE
IGNASDSTRIESFADLVAAATETDDGLYIAFNGSDNFGLFLDNVALQDLSADDIVFV
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECEEECCCCCCCEEEC
>Mature Secondary Structure 
TTVVGTAGVDILVGTEEKDRIWGLAGADDIEAGGGDDLVDGGAGDDRLASTSGYDRLDG
CEEEECCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GEGDDQITLIGTGGAVTGGAGTDTLVIDLANVSTSVRFSGEHGHGIIGYNTSDWEHIFFN
CCCCCEEEEEECCCEEECCCCCCEEEEEEECCCEEEEECCCCCCEEEECCCCCHHHHHHH
RIERLVLTTGSGNDRIFGASTDDIISTGGGNDIVGPYGTDGDDGTSMQGDDTINTGTGGD
HEEEEEEEECCCCCEEEECCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IINDTVGSNRIFAGDHDDIIFTTLSSTVIDGGTGWDRLTLLDEERTGDVTLDFARGFAST
CCCCCCCCCEEEECCCCCEEEEEECCEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCC
GTLINGIEVANINLGNGSDTLIAGNLLSLSAHLGEGDNYAAGSSGRDYIASGSGDDALYG
CCEECCEEEEEEECCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEC
DSGDDILISNGGNDVLVGGDGNDEIHDSGSRFDDGDTYIDGGSGDDLIQMVAPSGFIDGG
CCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCC
AGSDTLRVVGPLTGTHFDASTGMLGTSLVFTNIERFELSGDSGDDTIRTLGGDDQLAGNE
CCCCEEEEEECCCCCCCCCCCCCCEEEEEEECEEEEEECCCCCCCEEEECCCCCCCCCCC
GNDRLDGGAGKDVLWGGGGDDVMTGGAGADTYLWSSDTFSFSGVDRITDFDFDGGDVLRF
CCCCCCCCCCCCEEECCCCCCEEECCCCCCCEEECCCCEEECCCCCCEECCCCCCHHHHE
IGNASDSTRIESFADLVAAATETDDGLYIAFNGSDNFGLFLDNVALQDLSADDIVFV
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEECEEECCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]