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The map label for this gene is appB [H]

Identifier: 150396955

GI number: 150396955

Start: 1833128

End: 1834048

Strand: Reverse

Name: appB [H]

Synonym: Smed_1752

Alternate gene names: 150396955

Gene position: 1834048-1833128 (Counterclockwise)

Preceding gene: 150396956

Following gene: 150396954

Centisome position: 48.5

GC content: 61.13

Gene sequence:

>921_bases
ATGATGGCCTATATTGCGCGGCGACTGCTTCAGACGGTCGTCATCCTGCTCGGCATCAGCTTTGTCACCTTCATTCTGCT
GTACCTGATCCCGGCCGATCCGGCGAGGCAGATCGCCGGCCGCAGTGCAACGGCCCAGACCGTGGAGAACATCCGCGAAC
AGCTCGGGCTCAATCTGCCCTTCTACGAACAGTATATGCGTTATGTCGGGGGCCTCGTGCAGGGCGATTTCGGCCGATCC
TATCTGCAGAAGACCGAAGTTTCGACTTTGATCGCATCGCGCCTTCCGGCAAGTCTCCTGCTGATGGCCGGAGCCATTAC
CTGTGAACTGATCTTCGGGCTGACGATGGGCATCGTTGCAGCACTTCGGCGCGGCTCACGCACCGACGATACGCTGATGA
TCGCGTCATTTGTCGGTGTATCGGCGCCGCAGTTCGTGGTCGGAATCCTGCTCCTCTACGTTTTCGCCGTGAAGCTCGGC
TGGTTTCCGATCGGCGGCTACGGCACCTTCGCCCATCTGGTCTTGCCCTCCCTCACGCTCGGTTTTCTGGGGGCCGGCTG
GTATTCGCGCATGATGCGTTCGTCGCTGATCGAAGTGATGCGTCAGGATTTCATCCGTACGGCGCGCGCAACCGGCAACG
GTCGCGCCAAGGTCCTGTTCCGGCACGCAATGCCCAACGCGATCCTTCCTGTCATCGCGATGATCGGCATCGATATCGGC
CTGTTCATGTCAGGTATCGTGGTGGTGGAAAGCGTCTTCGGCTGGCCCGGGATCGGCCAGCTGGCCTGGCAGGCGATCCA
GCGGGTGGACATCCCGATCATCATGGGCGTCACGCTCGTCTCGGCGTTCGCGATCGTGCTCGGCAATCTGCTCGCCGACC
TCATCACGCCGCTTATCGACCCGCGCATCAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
TCATACCGGGTGCCGCGATCCTCGCGCTTGCGCTCGCCTTCAATCTGGTCGGTGATGCGCTGCGCGATGTTCTCGATCCG
ACGCAGCAGGGGAGGCATTG

Downstream 100 bases:

>100_bases
CGCGGGAAGAACAAACTGCAGCAACAGAAAGGAACTTCAGATGAGGAACTTGTTACTGGCCGGCGTCTGCGCCGCCGCAC
TGATGGGAAATCCCGCATTC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MMAYIARRLLQTVVILLGISFVTFILLYLIPADPARQIAGRSATAQTVENIREQLGLNLPFYEQYMRYVGGLVQGDFGRS
YLQKTEVSTLIASRLPASLLLMAGAITCELIFGLTMGIVAALRRGSRTDDTLMIASFVGVSAPQFVVGILLLYVFAVKLG
WFPIGGYGTFAHLVLPSLTLGFLGAGWYSRMMRSSLIEVMRQDFIRTARATGNGRAKVLFRHAMPNAILPVIAMIGIDIG
LFMSGIVVVESVFGWPGIGQLAWQAIQRVDIPIIMGVTLVSAFAIVLGNLLADLITPLIDPRIKLR

Sequences:

>Translated_306_residues
MMAYIARRLLQTVVILLGISFVTFILLYLIPADPARQIAGRSATAQTVENIREQLGLNLPFYEQYMRYVGGLVQGDFGRS
YLQKTEVSTLIASRLPASLLLMAGAITCELIFGLTMGIVAALRRGSRTDDTLMIASFVGVSAPQFVVGILLLYVFAVKLG
WFPIGGYGTFAHLVLPSLTLGFLGAGWYSRMMRSSLIEVMRQDFIRTARATGNGRAKVLFRHAMPNAILPVIAMIGIDIG
LFMSGIVVVESVFGWPGIGQLAWQAIQRVDIPIIMGVTLVSAFAIVLGNLLADLITPLIDPRIKLR
>Mature_306_residues
MMAYIARRLLQTVVILLGISFVTFILLYLIPADPARQIAGRSATAQTVENIREQLGLNLPFYEQYMRYVGGLVQGDFGRS
YLQKTEVSTLIASRLPASLLLMAGAITCELIFGLTMGIVAALRRGSRTDDTLMIASFVGVSAPQFVVGILLLYVFAVKLG
WFPIGGYGTFAHLVLPSLTLGFLGAGWYSRMMRSSLIEVMRQDFIRTARATGNGRAKVLFRHAMPNAILPVIAMIGIDIG
LFMSGIVVVESVFGWPGIGQLAWQAIQRVDIPIIMGVTLVSAFAIVLGNLLADLITPLIDPRIKLR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=38.8888888888889, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=33.1360946745562, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=36.5030674846626, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789888, Length=307, Percent_Identity=33.2247557003257, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=33.8762214983713, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=24.8618784530387, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787550, Length=332, Percent_Identity=25, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33395; Mature: 33395

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]