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The map label for this gene is fabZ [H]

Identifier: 150396943

GI number: 150396943

Start: 1820555

End: 1821031

Strand: Reverse

Name: fabZ [H]

Synonym: Smed_1740

Alternate gene names: 150396943

Gene position: 1821031-1820555 (Counterclockwise)

Preceding gene: 150396944

Following gene: 150396942

Centisome position: 48.15

GC content: 60.59

Gene sequence:

>477_bases
ATGCTCCTTGAATATTTCCAGATGATTGACCGGATCGAAAGCGTCGATCTGGCAGCCGGCCGTCTGGTGGCGCGCTCGAA
CGTGCCGGAAAAGAGCCCGGTGTTCGAAGGGCATTTCCCCGGCTATCCCCTGGTCCCCGGCGTGCTGCTTATCGAAACGA
TGGCGCAGGCATCCGGTTTTTTGGTGCTGGCCGCCACCAATTTCGCCGCAATGCCGTTTCTGATGACAGTCGATGGTGCG
AAGATGCGCAGCTTCGTCGAACCGAACGCCGAGCTTGAGATAGAGGCCCTGCTCGAGCACGAGGGGTCCGGCTTTGCCGT
GACGAAGGCCCGGATTGCGTCGGGCGGCAAGAAGATTTGCGATGCCAAGCTGAAACTGAGAACGATTCCGTTCGACCAGG
TGCCGCTCGGCGACATCGTGCGCAAGCGTGCGGAAGAGCTGGGGCTGATGGCCAGGACGGCCGGTTCGGAGAAATGA

Upstream 100 bases:

>100_bases
ACGGTTCGGTTCCTTTTCCCGATGCCGCCTGTCGCGCCCCGCGCTTGACAGGCGGCATCGGCATTTTTACTTGAGCGCGA
AACGAATGGGATGAGCCCTC

Downstream 100 bases:

>100_bases
ACATGACGAAATCCGCCAATGATGTGGTGATCACCGGAGTGGGCATCGTGACGAGCCAGGGCGTCGGCACCGAGCCTCAT
GTGGCGCTGCTCGGCGCAAC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MLLEYFQMIDRIESVDLAAGRLVARSNVPEKSPVFEGHFPGYPLVPGVLLIETMAQASGFLVLAATNFAAMPFLMTVDGA
KMRSFVEPNAELEIEALLEHEGSGFAVTKARIASGGKKICDAKLKLRTIPFDQVPLGDIVRKRAEELGLMARTAGSEK

Sequences:

>Translated_158_residues
MLLEYFQMIDRIESVDLAAGRLVARSNVPEKSPVFEGHFPGYPLVPGVLLIETMAQASGFLVLAATNFAAMPFLMTVDGA
KMRSFVEPNAELEIEALLEHEGSGFAVTKARIASGGKKICDAKLKLRTIPFDQVPLGDIVRKRAEELGLMARTAGSEK
>Mature_158_residues
MLLEYFQMIDRIESVDLAAGRLVARSNVPEKSPVFEGHFPGYPLVPGVLLIETMAQASGFLVLAATNFAAMPFLMTVDGA
KMRSFVEPNAELEIEALLEHEGSGFAVTKARIASGGKKICDAKLKLRTIPFDQVPLGDIVRKRAEELGLMARTAGSEK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=123, Percent_Identity=32.520325203252, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17150; Mature: 17150

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEYFQMIDRIESVDLAAGRLVARSNVPEKSPVFEGHFPGYPLVPGVLLIETMAQASGF
CHHHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
LVLAATNFAAMPFLMTVDGAKMRSFVEPNAELEIEALLEHEGSGFAVTKARIASGGKKIC
EEEEECCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCHHEE
DAKLKLRTIPFDQVPLGDIVRKRAEELGLMARTAGSEK
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLLEYFQMIDRIESVDLAAGRLVARSNVPEKSPVFEGHFPGYPLVPGVLLIETMAQASGF
CHHHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
LVLAATNFAAMPFLMTVDGAKMRSFVEPNAELEIEALLEHEGSGFAVTKARIASGGKKIC
EEEEECCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCHHEE
DAKLKLRTIPFDQVPLGDIVRKRAEELGLMARTAGSEK
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA