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The map label for this gene is msbB2 [H]

Identifier: 150396939

GI number: 150396939

Start: 1816048

End: 1816971

Strand: Reverse

Name: msbB2 [H]

Synonym: Smed_1736

Alternate gene names: 150396939

Gene position: 1816971-1816048 (Counterclockwise)

Preceding gene: 150396940

Following gene: 150396935

Centisome position: 48.04

GC content: 61.58

Gene sequence:

>924_bases
ATGCTGATCACAAGGCTGGTGCTTGCTGCGGATCGTTTCCGCCAGTGGCTGATCGCGCAGTTCGTCCTGCTGCTTCTCAC
GATCCTCAAGCTTTTCCCCCCGGACAAAGCGATCAATTTCATGGATCGCGTTGCCCGCTGGATCGGTCCGAAGACCGGTC
GCCACAAGCTGACGCTGATCAATCTGCGCAATGCGTTTCCCGAGAAGAGCGATGCCGAGATCGAAGAGATCGCGCTGGAA
AGCTGGGGCAACATGGGACGCCTCGCTGCCGAGTATGTCTTTCTCGATCGGCTCTTCGACTTCGATCCGGCGCGCATTGA
GGCGGGCAGGGTGGATGTTTCCGGCATCCCGCTCTTCCTGGAACTGCGCGACAATCCGCGGCCCTTCATCGTCTTCACGG
CCCATAGCGGCAATTTCGAAATGCTGCCGGTCGCAGGCTCCGCTTTCGGTCTGGACGTGACGGTGCTCTTCCGTCCTCCG
AACAATCCCTACCTCGCCGACCGGGTATTTGAATTCCGCAGGCAGCGCATGGGCAACCTCGTGCCGTCGCACGCCGGCTC
CTCCTTCGCCCTGGCCAGGCAGCTCGAACGCGGCGGCGGCGTCGGCGTCCTCGTCGACCAGAAGTTTCGCAAGGGTCTGA
AGACGAAATTCTTCGGGCAGGACGTGCAGACGAATCCGCTGCTAGCCAAGCTCGTCCGCCAGTTCAATTGCGAGGTCTAC
CCGGCCCGCTGCATTCGGCTACCCGGCAACCGCTTCCGGCTGGAGCTCGAGCCGGCGGTCGAAATCCCCCGCAGAACCGA
CGGCAGCGTCGATGTCACGGCAACGGCGCAGATGCTGAACGACAAGGTCGAGAGCTGGGTTCGCGAATATCCGGGCCAGT
GGCTCTGGTATCATGATCGCTGGCACATCAAGCGGACTCTTTGA

Upstream 100 bases:

>100_bases
ACCGAGGTCGGACTTAACGACATCGACCGCGCGCTGGAGCGGATGGAGTCGCGCCAGATCTTCGGCAAGATCGTGCTGCG
GATGGACTGATCGCGTGCGG

Downstream 100 bases:

>100_bases
GCCGGATCTTCAAAAGCACATCGCTTTCCCTCCGAAACTGCCGTCTCCTTAAATTGGCGCCGATTGTAGGCTTGTCTGCG
AACGCGGGCGCGCAAAGAGA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLITRLVLAADRFRQWLIAQFVLLLLTILKLFPPDKAINFMDRVARWIGPKTGRHKLTLINLRNAFPEKSDAEIEEIALE
SWGNMGRLAAEYVFLDRLFDFDPARIEAGRVDVSGIPLFLELRDNPRPFIVFTAHSGNFEMLPVAGSAFGLDVTVLFRPP
NNPYLADRVFEFRRQRMGNLVPSHAGSSFALARQLERGGGVGVLVDQKFRKGLKTKFFGQDVQTNPLLAKLVRQFNCEVY
PARCIRLPGNRFRLELEPAVEIPRRTDGSVDVTATAQMLNDKVESWVREYPGQWLWYHDRWHIKRTL

Sequences:

>Translated_307_residues
MLITRLVLAADRFRQWLIAQFVLLLLTILKLFPPDKAINFMDRVARWIGPKTGRHKLTLINLRNAFPEKSDAEIEEIALE
SWGNMGRLAAEYVFLDRLFDFDPARIEAGRVDVSGIPLFLELRDNPRPFIVFTAHSGNFEMLPVAGSAFGLDVTVLFRPP
NNPYLADRVFEFRRQRMGNLVPSHAGSSFALARQLERGGGVGVLVDQKFRKGLKTKFFGQDVQTNPLLAKLVRQFNCEVY
PARCIRLPGNRFRLELEPAVEIPRRTDGSVDVTATAQMLNDKVESWVREYPGQWLWYHDRWHIKRTL
>Mature_307_residues
MLITRLVLAADRFRQWLIAQFVLLLLTILKLFPPDKAINFMDRVARWIGPKTGRHKLTLINLRNAFPEKSDAEIEEIALE
SWGNMGRLAAEYVFLDRLFDFDPARIEAGRVDVSGIPLFLELRDNPRPFIVFTAHSGNFEMLPVAGSAFGLDVTVLFRPP
NNPYLADRVFEFRRQRMGNLVPSHAGSSFALARQLERGGGVGVLVDQKFRKGLKTKFFGQDVQTNPLLAKLVRQFNCEVY
PARCIRLPGNRFRLELEPAVEIPRRTDGSVDVTATAQMLNDKVESWVREYPGQWLWYHDRWHIKRTL

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35291; Mature: 35291

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITRLVLAADRFRQWLIAQFVLLLLTILKLFPPDKAINFMDRVARWIGPKTGRHKLTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
NLRNAFPEKSDAEIEEIALESWGNMGRLAAEYVFLDRLFDFDPARIEAGRVDVSGIPLFL
EECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCEEEE
ELRDNPRPFIVFTAHSGNFEMLPVAGSAFGLDVTVLFRPPNNPYLADRVFEFRRQRMGNL
EECCCCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
VPSHAGSSFALARQLERGGGVGVLVDQKFRKGLKTKFFGQDVQTNPLLAKLVRQFNCEVY
CCCCCCCHHHHHHHHHHCCCEEEEECHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCEE
PARCIRLPGNRFRLELEPAVEIPRRTDGSVDVTATAQMLNDKVESWVREYPGQWLWYHDR
EEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEECCE
WHIKRTL
EEEEECC
>Mature Secondary Structure
MLITRLVLAADRFRQWLIAQFVLLLLTILKLFPPDKAINFMDRVARWIGPKTGRHKLTLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
NLRNAFPEKSDAEIEEIALESWGNMGRLAAEYVFLDRLFDFDPARIEAGRVDVSGIPLFL
EECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCEEEE
ELRDNPRPFIVFTAHSGNFEMLPVAGSAFGLDVTVLFRPPNNPYLADRVFEFRRQRMGNL
EECCCCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCC
VPSHAGSSFALARQLERGGGVGVLVDQKFRKGLKTKFFGQDVQTNPLLAKLVRQFNCEVY
CCCCCCCHHHHHHHHHHCCCEEEEECHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCEE
PARCIRLPGNRFRLELEPAVEIPRRTDGSVDVTATAQMLNDKVESWVREYPGQWLWYHDR
EEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEECCE
WHIKRTL
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11115111; 11292750; 12384590; 9171415 [H]