BacMap

Definition	Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession	NC_009636
Length	3,781,904

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The map label for this gene is fabG [H]

Identifier: 150396910

GI number: 150396910

Start: 1785786

End: 1786553

Strand: Reverse

Name: fabG [H]

Synonym: Smed_1707

Alternate gene names: 150396910

Gene position: 1786553-1785786 (Counterclockwise)

Preceding gene: 150396912

Following gene: 150396909

Centisome position: 47.24

GC content: 60.81

Gene sequence:

>768_bases
ATGAATCTGGCTGGCAAAGTCGTACTCGTAACGGGGGCGGCGCGTGGGATCGGGGCGGCCATTTCTGTCCGGCTCTGGCA
GGAGGGCATGTTTGTCTATGCCGCCGATATTGATGAGGAAGCGCTGGCCGGTGCGGCGCCGGCAGGCGCGGATGAACGTT
GGATTCCGGCCGGGGTGGACATTACCGATCGGGGTTCGATCGACAGGCTCATTGCCGCAATCGGCCTGCGGTTCGGCGTC
CTCCATGGACTGGTCAACAACGCTGCGATGCTTGACGCAAGTCTCTTAGCCGAACTGGACTATGACCGCTACCGCCGCGT
AGTGGCGACGAACCTCGACGGAGCGTTGCTTTGCGTATTGAGCGCGCTTGAACTGATCAAAGCTTCCGCACCTTCGGCCA
TCGTAAATATCGCCTCTATCATGGGTATGGCCGGGTTGCGCGACGCAATTCCTTATTCGACGGCCAAGGCCGGTCTCATC
AATATGACGCGCAATCTGGCGGTGGAATTGGCGCCCCAGTCCATCCGGGTGAACGCGGTCGCCCCCGGTTTCATCGACAC
GCGAATGGCGCGGCTTGCCGATGGCAGCAGCGAATATGCTACCGAAGAATTCAGGGAAGTCTATTTGAAGCACCGGCGGC
TCCCGCTGGGTCATCCCGGAACCGCCGAGGATATCGCCGGACCCGTCGCGTTCCTCCTTTCCTCCGACGCCCGCTACATC
ACCGGCCATACGCTGGTGGTGGATGGTGGGGTTACTGCAACCTATTGA

Upstream 100 bases:

>100_bases
GGAGTCTTTCCATGGTGATTGACTATAGTATACCGTATTCTGTATAGGAAGCCATCGCTATTGCACGTGATCCGTCGCGC
GCGTCGATAGGAGGATTGAA

Downstream 100 bases:

>100_bases
TCGGACAATCCAATGACAGCCCATCTTTCTTCCGCCACATCCGTCCCCGGCTTCGACGCGCCGCCAATGCTGCGCATCTC
CTCCGTCGCCTGTGTCCCCT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNLAGKVVLVTGAARGIGAAISVRLWQEGMFVYAADIDEEALAGAAPAGADERWIPAGVDITDRGSIDRLIAAIGLRFGV
LHGLVNNAAMLDASLLAELDYDRYRRVVATNLDGALLCVLSALELIKASAPSAIVNIASIMGMAGLRDAIPYSTAKAGLI
NMTRNLAVELAPQSIRVNAVAPGFIDTRMARLADGSSEYATEEFREVYLKHRRLPLGHPGTAEDIAGPVAFLLSSDARYI
TGHTLVVDGGVTATY

Sequences:

>Translated_255_residues
MNLAGKVVLVTGAARGIGAAISVRLWQEGMFVYAADIDEEALAGAAPAGADERWIPAGVDITDRGSIDRLIAAIGLRFGV
LHGLVNNAAMLDASLLAELDYDRYRRVVATNLDGALLCVLSALELIKASAPSAIVNIASIMGMAGLRDAIPYSTAKAGLI
NMTRNLAVELAPQSIRVNAVAPGFIDTRMARLADGSSEYATEEFREVYLKHRRLPLGHPGTAEDIAGPVAFLLSSDARYI
TGHTLVVDGGVTATY
>Mature_255_residues
MNLAGKVVLVTGAARGIGAAISVRLWQEGMFVYAADIDEEALAGAAPAGADERWIPAGVDITDRGSIDRLIAAIGLRFGV
LHGLVNNAAMLDASLLAELDYDRYRRVVATNLDGALLCVLSALELIKASAPSAIVNIASIMGMAGLRDAIPYSTAKAGLI
NMTRNLAVELAPQSIRVNAVAPGFIDTRMARLADGSSEYATEEFREVYLKHRRLPLGHPGTAEDIAGPVAFLLSSDARYI
TGHTLVVDGGVTATY

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=34.2741935483871, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=33.8582677165354, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=33.0769230769231, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=32.156862745098, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=31.640625, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=31.25, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=32.0158102766798, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI59889578, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=29.8449612403101, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503301, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=36.1111111111111, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=32.8125, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=29.5275590551181, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.9212598425197, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.0395256916996, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=30.1960784313725, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=28.6274509803922, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=28.5171102661597, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=29.6875, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=34.1085271317829, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=33.201581027668, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=32.3420074349442, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.9701492537313, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=33.8345864661654, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=30.5343511450382, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=33.210332103321, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=31.496062992126, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=32.6996197718631, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=29.6577946768061, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=33.0769230769231, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.9160305343511, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=31.6793893129771, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=29.8039215686275, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=30.2238805970149, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=32.8358208955224, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.4820717131474, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=29.9242424242424, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=30.7116104868914, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.6245353159851, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=31.6981132075472, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=32.4427480916031, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=30.8880308880309, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32563809, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=29.1187739463602, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=27.1356783919598, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=28.0769230769231, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322227, Length=218, Percent_Identity=27.9816513761468, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=27.6041666666667, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=34.375, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=34.2412451361868, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.9920948616601, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=32.4110671936759, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.0739299610895, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=33.7254901960784, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=31.9230769230769, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI22024069, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116007236, Length=255, Percent_Identity=26.2745098039216, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573296, Length=206, Percent_Identity=29.126213592233, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=198, Percent_Identity=28.7878787878788, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=25.9067357512953, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921754, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26832; Mature: 26832

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAGKVVLVTGAARGIGAAISVRLWQEGMFVYAADIDEEALAGAAPAGADERWIPAGVD
CCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCC
ITDRGSIDRLIAAIGLRFGVLHGLVNNAAMLDASLLAELDYDRYRRVVATNLDGALLCVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
SALELIKASAPSAIVNIASIMGMAGLRDAIPYSTAKAGLINMTRNLAVELAPQSIRVNAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEECCCEEEEEEE
APGFIDTRMARLADGSSEYATEEFREVYLKHRRLPLGHPGTAEDIAGPVAFLLSSDARYI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
TGHTLVVDGGVTATY
ECEEEEEECCEEECC
>Mature Secondary Structure
MNLAGKVVLVTGAARGIGAAISVRLWQEGMFVYAADIDEEALAGAAPAGADERWIPAGVD
CCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEECCCHHHHCCCCCCCCCCCCCCCCCC
ITDRGSIDRLIAAIGLRFGVLHGLVNNAAMLDASLLAELDYDRYRRVVATNLDGALLCVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
SALELIKASAPSAIVNIASIMGMAGLRDAIPYSTAKAGLINMTRNLAVELAPQSIRVNAV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEECCCEEEEEEE
APGFIDTRMARLADGSSEYATEEFREVYLKHRRLPLGHPGTAEDIAGPVAFLLSSDARYI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
TGHTLVVDGGVTATY
ECEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]