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The map label for this gene is ycgM [C]

Identifier: 150396896

GI number: 150396896

Start: 1772592

End: 1773278

Strand: Direct

Name: ycgM [C]

Synonym: Smed_1692

Alternate gene names: 150396896

Gene position: 1772592-1773278 (Clockwise)

Preceding gene: 150396895

Following gene: 150396897

Centisome position: 46.87

GC content: 61.86

Gene sequence:

>687_bases
ATGCAGACCGTTTTGACACCCCCGCCCCTCGTCCTGCTGCCGATCTCGGGTAGTTCCGTCGGCTTTCCGGTGCGCCGGGT
CTATTGTGTCGGCCGCAACTATGCAGCCCATGCTCGCGAAATGGGCCATGACCCGGATCGCGAGGCACCTTTCTTCTTTC
AGAAAAACGCCGACAATATTCTGCTGCCGGGCGAGGATTTCCCCTACCCGCCGCTCTCGTCCGACGTGCATCACGAAGTT
GAGCTGATTGTCGCAATGCGCAGCGGCGGAGCTGACATTCCCGCTGGAGAAGCAGGCGATCACATCTTCGGTTACGGTGT
CGGCATCGACTTCACGCGGCGTGACCTGCAGGCGGAAGCGAAGAAGGCCGGCAAGCCCTGGACGGCCGCCAAGGCGTTCG
AACATTCAGCCCCGGTATCCGCGATCGTTCCGGTCACTGCGATAGGCCATCCCGTAAGCGGCAACATATGGCTCAAGGTA
AATGGCGAATTGCGCCAGCAGGGGGATCTCGACCAGATGATCTGGAAAGTGCCGGAAATCATCGCCGAGCTCTCCCGCCT
TTTCACTCTCGCTCCGGGCGATATCATCATGACCGGGACGCCGGCGGGTGTCGGCCCCGTCACGCGCGGCGATGTCGTCG
CCTGCGGCGTCGATGGGATCGGCGCGATGTCGGTCACGATCGTTTGA

Upstream 100 bases:

>100_bases
CGGAGTCGCTCCAATTTCGCCAGGGCGGAATCCGATGCGTCGATATTGTCGAACCAGCTCTTCGGGCGAAGCCGAGAGAG
AATGACGGAGCCGGACGTTC

Downstream 100 bases:

>100_bases
ACGGGCGGAACGAAGAGCGCGCTTGATTAAAGGACACAGCCGCAACTCTGAAAGGACCCTTGCATGCCGCTCTACGCTCT
AGGACCGCTTAGACCACAGA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQTVLTPPPLVLLPISGSSVGFPVRRVYCVGRNYAAHAREMGHDPDREAPFFFQKNADNILLPGEDFPYPPLSSDVHHEV
ELIVAMRSGGADIPAGEAGDHIFGYGVGIDFTRRDLQAEAKKAGKPWTAAKAFEHSAPVSAIVPVTAIGHPVSGNIWLKV
NGELRQQGDLDQMIWKVPEIIAELSRLFTLAPGDIIMTGTPAGVGPVTRGDVVACGVDGIGAMSVTIV

Sequences:

>Translated_228_residues
MQTVLTPPPLVLLPISGSSVGFPVRRVYCVGRNYAAHAREMGHDPDREAPFFFQKNADNILLPGEDFPYPPLSSDVHHEV
ELIVAMRSGGADIPAGEAGDHIFGYGVGIDFTRRDLQAEAKKAGKPWTAAKAFEHSAPVSAIVPVTAIGHPVSGNIWLKV
NGELRQQGDLDQMIWKVPEIIAELSRLFTLAPGDIIMTGTPAGVGPVTRGDVVACGVDGIGAMSVTIV
>Mature_228_residues
MQTVLTPPPLVLLPISGSSVGFPVRRVYCVGRNYAAHAREMGHDPDREAPFFFQKNADNILLPGEDFPYPPLSSDVHHEV
ELIVAMRSGGADIPAGEAGDHIFGYGVGIDFTRRDLQAEAKKAGKPWTAAKAFEHSAPVSAIVPVTAIGHPVSGNIWLKV
NGELRQQGDLDQMIWKVPEIIAELSRLFTLAPGDIIMTGTPAGVGPVTRGDVVACGVDGIGAMSVTIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=43.8423645320197, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=44.5, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=44.8979591836735, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI156231349, Length=230, Percent_Identity=36.5217391304348, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI40786394, Length=230, Percent_Identity=35.2173913043478, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787428, Length=205, Percent_Identity=41.4634146341463, Blast_Score=154, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=39.5833333333333, Blast_Score=156, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6324161, Length=223, Percent_Identity=35.8744394618834, Blast_Score=131, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=32.1951219512195, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572127, Length=211, Percent_Identity=32.2274881516588, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24663695, Length=211, Percent_Identity=28.9099526066351, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24254; Mature: 24254

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVLTPPPLVLLPISGSSVGFPVRRVYCVGRNYAAHAREMGHDPDREAPFFFQKNADNI
CCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEE
LLPGEDFPYPPLSSDVHHEVELIVAMRSGGADIPAGEAGDHIFGYGVGIDFTRRDLQAEA
EECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
KKAGKPWTAAKAFEHSAPVSAIVPVTAIGHPVSGNIWLKVNGELRQQGDLDQMIWKVPEI
HHCCCCCHHHHHHHCCCCCEEEEEHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
IAELSRLFTLAPGDIIMTGTPAGVGPVTRGDVVACGVDGIGAMSVTIV
HHHHHHHEEECCCCEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MQTVLTPPPLVLLPISGSSVGFPVRRVYCVGRNYAAHAREMGHDPDREAPFFFQKNADNI
CCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCEE
LLPGEDFPYPPLSSDVHHEVELIVAMRSGGADIPAGEAGDHIFGYGVGIDFTRRDLQAEA
EECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
KKAGKPWTAAKAFEHSAPVSAIVPVTAIGHPVSGNIWLKVNGELRQQGDLDQMIWKVPEI
HHCCCCCHHHHHHHCCCCCEEEEEHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHH
IAELSRLFTLAPGDIIMTGTPAGVGPVTRGDVVACGVDGIGAMSVTIV
HHHHHHHEEECCCCEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]