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The map label for this gene is cobT [H]

Identifier: 150396812

GI number: 150396812

Start: 1699083

End: 1700099

Strand: Reverse

Name: cobT [H]

Synonym: Smed_1603

Alternate gene names: 150396812

Gene position: 1700099-1699083 (Counterclockwise)

Preceding gene: 150396816

Following gene: 150396811

Centisome position: 44.95

GC content: 65.59

Gene sequence:

>1017_bases
ATGAGCGCCAGCGGCCTGCCGTTTGATGATTTTCGCGCGTTACTGCGCAACCTGCCTGGCCCCGATACGGCGGCACTCGT
TGCCGCACGCGAGCGGGACGGGCAATTGACGAAGCCGCCCGGCGCACTGGGGCGCCTGGAGGAAATCGCATTCTGGCTTG
CCGCCTGGACGGGCCGCCCGCCGGCCGTCAACAGGCCGCTCGTGGCGATTTTCGCCGGCAACCACGGCGTGACCCGTCAG
GGAGTGACGCCGTTTCCGGCTTCGGTCACCGCGCAGATGGTCGAGAACTTCGCCGCCGGTGGGGCTGCCATCAACCAGAT
CTGCGTAGCGCATGATCTCGGCCTCAAAGTCTTCGATCTGGCCCTTGATTACCCGACCGGCGATATCACCGAAGAACCCG
CTCTGTCCGAGCGTGATTGCGCCGCTACCATGGCCTTCGGCATGGAGGCCATCGCCGGCGGCACGGACCTGCTTTGCATC
GGCGAGATGGGAATTGGCAATACAACGATCGCAGCAGCCATCAATCTCGGCCTTTACGGCGGCACTGCCGAGGAATGGGT
GGGGCCGGGAACCGGCTCGGAAGGAGAGGTTCTCAAGCGCAAGATTGCGGCGGTGAAAAAGGCCGTGGCACTGCACCGCG
ACCACTTGTCCGATCCGCTGGAAGTCATGCGCCGGCTTGGCGGCCGCGAAATCGCGGCCATGGCGGGCGCCATTCTCGCG
GCGCGCATGCAAAAGGTACCCGTCATCATCGACGGTTATGTCGCAACCGCAGCCGCGGCGATCCTCAAGGCCGCCAATCC
GGCCGCGCTCGACCATTGCCTCATCGGGCACGTTTCAAGTGAGCCCGGCCACATGCGCGCGATCGAGAAGCTCGGCAAGA
CCCCGCTCCTGGCCCTCGGGATGCGGCTTGGCGAAGGCACAGGTGCGGCCCTTGCAGCGGGTATCGTCAAAGCGGCGGCG
GCGTGCCACAGCGGCATGGCGACCTTTGCGCAGGCTGGCGTCAGTAACAAGGTGTAG

Upstream 100 bases:

>100_bases
GATCATGCGAGACGACGGCAAATGGCGCAAATGCCGTTGCCGCACGCGCCCTCACGCTCTATGACGAGCCCGGAACGAGT
TCACATCGCAAGGATTGTCC

Downstream 100 bases:

>100_bases
CATAGGGAGTAGGCCCGAGACGCGTTACCCGTTTGCTGTCGATTGCCCGGCCTGCATGCTATCCTCATGGTGCCGCCTTG
GATTCGCCTTAATCGGAACG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSASGLPFDDFRALLRNLPGPDTAALVAARERDGQLTKPPGALGRLEEIAFWLAAWTGRPPAVNRPLVAIFAGNHGVTRQ
GVTPFPASVTAQMVENFAAGGAAINQICVAHDLGLKVFDLALDYPTGDITEEPALSERDCAATMAFGMEAIAGGTDLLCI
GEMGIGNTTIAAAINLGLYGGTAEEWVGPGTGSEGEVLKRKIAAVKKAVALHRDHLSDPLEVMRRLGGREIAAMAGAILA
ARMQKVPVIIDGYVATAAAAILKAANPAALDHCLIGHVSSEPGHMRAIEKLGKTPLLALGMRLGEGTGAALAAGIVKAAA
ACHSGMATFAQAGVSNKV

Sequences:

>Translated_338_residues
MSASGLPFDDFRALLRNLPGPDTAALVAARERDGQLTKPPGALGRLEEIAFWLAAWTGRPPAVNRPLVAIFAGNHGVTRQ
GVTPFPASVTAQMVENFAAGGAAINQICVAHDLGLKVFDLALDYPTGDITEEPALSERDCAATMAFGMEAIAGGTDLLCI
GEMGIGNTTIAAAINLGLYGGTAEEWVGPGTGSEGEVLKRKIAAVKKAVALHRDHLSDPLEVMRRLGGREIAAMAGAILA
ARMQKVPVIIDGYVATAAAAILKAANPAALDHCLIGHVSSEPGHMRAIEKLGKTPLLALGMRLGEGTGAALAAGIVKAAA
ACHSGMATFAQAGVSNKV
>Mature_337_residues
SASGLPFDDFRALLRNLPGPDTAALVAARERDGQLTKPPGALGRLEEIAFWLAAWTGRPPAVNRPLVAIFAGNHGVTRQG
VTPFPASVTAQMVENFAAGGAAINQICVAHDLGLKVFDLALDYPTGDITEEPALSERDCAATMAFGMEAIAGGTDLLCIG
EMGIGNTTIAAAINLGLYGGTAEEWVGPGTGSEGEVLKRKIAAVKKAVALHRDHLSDPLEVMRRLGGREIAAMAGAILAA
RMQKVPVIIDGYVATAAAAILKAANPAALDHCLIGHVSSEPGHMRAIEKLGKTPLLALGMRLGEGTGAALAAGIVKAAAA
CHSGMATFAQAGVSNKV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=341, Percent_Identity=32.258064516129, Blast_Score=158, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 34649; Mature: 34518

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASGLPFDDFRALLRNLPGPDTAALVAARERDGQLTKPPGALGRLEEIAFWLAAWTGRP
CCCCCCCHHHHHHHHHHCCCCCHHHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PAVNRPLVAIFAGNHGVTRQGVTPFPASVTAQMVENFAAGGAAINQICVAHDLGLKVFDL
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALDYPTGDITEEPALSERDCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAINLGLYG
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCC
GTAEEWVGPGTGSEGEVLKRKIAAVKKAVALHRDHLSDPLEVMRRLGGREIAAMAGAILA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHH
ARMQKVPVIIDGYVATAAAAILKAANPAALDHCLIGHVSSEPGHMRAIEKLGKTPLLALG
HHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHH
MRLGEGTGAALAAGIVKAAAACHSGMATFAQAGVSNKV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SASGLPFDDFRALLRNLPGPDTAALVAARERDGQLTKPPGALGRLEEIAFWLAAWTGRP
CCCCCCHHHHHHHHHHCCCCCHHHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PAVNRPLVAIFAGNHGVTRQGVTPFPASVTAQMVENFAAGGAAINQICVAHDLGLKVFDL
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALDYPTGDITEEPALSERDCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAINLGLYG
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCC
GTAEEWVGPGTGSEGEVLKRKIAAVKKAVALHRDHLSDPLEVMRRLGGREIAAMAGAILA
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHH
ARMQKVPVIIDGYVATAAAAILKAANPAALDHCLIGHVSSEPGHMRAIEKLGKTPLLALG
HHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHH
MRLGEGTGAALAAGIVKAAAACHSGMATFAQAGVSNKV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]