BacMap

Definition	Sinorhizobium medicae WSM419 chromosome, complete genome.
Accession	NC_009636
Length	3,781,904

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The map label for this gene is fabG [H]

Identifier: 150396801

GI number: 150396801

Start: 1689350

End: 1690054

Strand: Reverse

Name: fabG [H]

Synonym: Smed_1592

Alternate gene names: 150396801

Gene position: 1690054-1689350 (Counterclockwise)

Preceding gene: 150396802

Following gene: 150396796

Centisome position: 44.69

GC content: 62.55

Gene sequence:

>705_bases
ATGAGCGAACAGAAGGTGGCAATCGTTACGGCCGGCGGTTCCGGTATGGGGGCCGGCGCGGCACGGCGGATGGCGGCGGA
GGGCTACAAGGTCGCCGTCCTCTCATCGTCGGGCAAGGGCGAGGCGCTCGCCAGGGAGCTCGGCGGTATCGGCGTCACCG
GATCGAACCAGTCAAGTGACGATTTGAAGCGGCTCGTCGATGCGGCGTATGACGCCTGGGGTCGTGTGGACGCCCTGATC
AATTCGGCAGGACATGGCCCTCGCGCGCCCGTACTCGAGCTCACTGACGAGGAGTGGCACAAAGGCATGGAGGTCTATTT
CCTCAATGTCGTGCGGCCGACCCGGCTGGTGACGCCGATTATGATGGAGCAGAAATCCGGCAGCATCGTCAATATTTCCA
CCTATGCCACCTTCGAACCGGACCCCCTGTTTCCGACGTCGGGGGTCTTCCGTTCCGGACTTGCCGCTTTCACCAAGCTT
TTCGCCGACCGCTATGCCCCCGACAATATCCGCATGAACAATGTTCTGCCGGGCTTTATCGACAGTCTGCCGGAAACCGA
GGAACGGCGCCAGCGCATCCCGATAGGGCGTTACGGGACAACGGAGGAGGTGGCCGAGCTGGTTGCGCTGCTCGCCAGCG
ATCGTGGGGGTTACATCACCGGTCAAAACATCCGGGTCGACGGTGGCATCACCCGATCCGTCTGA

Upstream 100 bases:

>100_bases
TACCGCGCCCCTATTTAGAACGCCGTCTTCAGAAATTCTCATTTGATGCCGACGCGCGGGACTGCTTCAACTGCGTTCTC
GCGAGCAAAAGGAGCACAAG

Downstream 100 bases:

>100_bases
CACTTCCGACCACAAATGTACCGGCCGTAGTCTAATGGACGATAAACTCGCCCTTGAGTGCCCTCCACTCCGAGGCCGAG
ATCAATTTGCGGTGCACGTA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSEQKVAIVTAGGSGMGAGAARRMAAEGYKVAVLSSSGKGEALARELGGIGVTGSNQSSDDLKRLVDAAYDAWGRVDALI
NSAGHGPRAPVLELTDEEWHKGMEVYFLNVVRPTRLVTPIMMEQKSGSIVNISTYATFEPDPLFPTSGVFRSGLAAFTKL
FADRYAPDNIRMNNVLPGFIDSLPETEERRQRIPIGRYGTTEEVAELVALLASDRGGYITGQNIRVDGGITRSV

Sequences:

>Translated_234_residues
MSEQKVAIVTAGGSGMGAGAARRMAAEGYKVAVLSSSGKGEALARELGGIGVTGSNQSSDDLKRLVDAAYDAWGRVDALI
NSAGHGPRAPVLELTDEEWHKGMEVYFLNVVRPTRLVTPIMMEQKSGSIVNISTYATFEPDPLFPTSGVFRSGLAAFTKL
FADRYAPDNIRMNNVLPGFIDSLPETEERRQRIPIGRYGTTEEVAELVALLASDRGGYITGQNIRVDGGITRSV
>Mature_233_residues
SEQKVAIVTAGGSGMGAGAARRMAAEGYKVAVLSSSGKGEALARELGGIGVTGSNQSSDDLKRLVDAAYDAWGRVDALIN
SAGHGPRAPVLELTDEEWHKGMEVYFLNVVRPTRLVTPIMMEQKSGSIVNISTYATFEPDPLFPTSGVFRSGLAAFTKLF
ADRYAPDNIRMNNVLPGFIDSLPETEERRQRIPIGRYGTTEEVAELVALLASDRGGYITGQNIRVDGGITRSV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=33.8775510204082, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=29.9145299145299, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=29.4820717131474, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=28.1632653061224, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI66933014, Length=185, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=33.8888888888889, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=28.1124497991968, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=31.0924369747899, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=30.241935483871, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=30.6122448979592, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790717, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.5546558704453, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=33.8709677419355, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=34.136546184739, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=31.6, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=28.5123966942149, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=32.1705426356589, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=32.0987654320988, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.4182509505703, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=30.3846153846154, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.0992366412214, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=27.5471698113208, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=27.0588235294118, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=29.0697674418605, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=28.5171102661597, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=26.1194029850746, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=30.1020408163265, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=27.4611398963731, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=32.5102880658436, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=32.3770491803279, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=30.7377049180328, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.7449392712551, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=29.2, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25067; Mature: 24935

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKVAIVTAGGSGMGAGAARRMAAEGYKVAVLSSSGKGEALARELGGIGVTGSNQSSD
CCCCEEEEEEECCCCCCCHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHH
DLKRLVDAAYDAWGRVDALINSAGHGPRAPVLELTDEEWHKGMEVYFLNVVRPTRLVTPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCEEEEEEECCCHHHHHHH
MMEQKSGSIVNISTYATFEPDPLFPTSGVFRSGLAAFTKLFADRYAPDNIRMNNVLPGFI
HHCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHH
DSLPETEERRQRIPIGRYGTTEEVAELVALLASDRGGYITGQNIRVDGGITRSV
HCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCC
>Mature Secondary Structure 
SEQKVAIVTAGGSGMGAGAARRMAAEGYKVAVLSSSGKGEALARELGGIGVTGSNQSSD
CCCEEEEEEECCCCCCCHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHH
DLKRLVDAAYDAWGRVDALINSAGHGPRAPVLELTDEEWHKGMEVYFLNVVRPTRLVTPI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCCCEEEEEEECCCHHHHHHH
MMEQKSGSIVNISTYATFEPDPLFPTSGVFRSGLAAFTKLFADRYAPDNIRMNNVLPGFI
HHCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHH
DSLPETEERRQRIPIGRYGTTEEVAELVALLASDRGGYITGQNIRVDGGITRSV
HCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]