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The map label for this gene is hcaT [H]

Identifier: 150396766

GI number: 150396766

Start: 1648319

End: 1649542

Strand: Reverse

Name: hcaT [H]

Synonym: Smed_1556

Alternate gene names: 150396766

Gene position: 1649542-1648319 (Counterclockwise)

Preceding gene: 150396767

Following gene: 150396764

Centisome position: 43.62

GC content: 60.95

Gene sequence:

>1224_bases
ATGATTCCCTCCTCTGCTCCCGCGTTCGTAGCGGGGCCCCCGCCGCGCCATTTCGCACTCCGCATTGCGCTGCTCTTCTC
GGCGCCGTTGATCGTCAATGGTTTCGCCATGCCGTACTTTCCGGTCTGGCTCAGCAGCCTGTCGCTCAGCGATTTCGAAA
TCGGCATAGTGCTTGCGGTTCCCATGTTCGTCCGAGTGATCACCGCACCCTTGGCGGGCGTTCTTGCCGACCGTATTGGC
GAGCGGTCTATCGTTCTGATCTGGTCCGGGGTCCTGTCTTTCGCCGCTGCCATTATTCTTTTCCATGCGCAGCGTTTCTG
GCCAGTTCTCGTCATCTACACGCTGCAATCGGCGGTTTATTCCCCTTACATGCCGATCGTCGAGGCCATCGCCTTATCGG
GCGTTCGGCGCTGGGGCTTCGACTACGCGCAGATGCGTGTCTGGGGATCGGTCGCCTTTATCGGGGCGACGATGCTGGGT
GGCTGGCTGATCGGGATCGTCGGCGGCCAGATGGTCCTGCCGGCCATGGCCGCGGGTTTCGCGCTGGCCATTCTGTTGGC
CGTAGCGGCGCCGCGTGTCGGGCGGCCGCGCAGGCCGTCGCCGATTACCGCAATCACGGAGCCTCCGCCACAATCGCTGC
GCCAGACGGATCTGCAACTGCTCCTGGTCGGCGTGACGCTGATCAATAGCAGCCACGCGATGCTCTTCGCCTTCTCTGCC
ATTTACTGGCAACATATCGGCTACAGCGGCACGCAGATCGGCGTTCTCTGGAGTGCCGGCGTCGCGGCGGAAGTTCTGAT
GTTCTTCTTCGCCAAGGCGATCGTCCGCCGGTTCAGCGTCTGGACGATGATCTTCTCCGGCTGCCTGCTTGCTGTCATAC
GCTGGCTGATCTTCCCGATGGATCTCGGTTTTTCGGGCTATTTCGTTCTGCAATGCTTCCACGCCTTCACTTACGCGATC
ATGCATACGGGCATGCAGCACAAGCTGGTCGAGCGCGTCGCGGAGGAGCAGGAGGCATCGGCGCAGGGGCTGTATTTTTT
CTACACCGGCGTCTTCACGGCTATCTTCACCTTTCTGTCCGGCTATTTCTACGCCTGGTTCGGTGTCGACGGCTTCTACT
CCATGTCGGTGGTTGCGCTGTCGGGGTGCCTCTTCACTTTTCTGGGCTGGTTTCTTCAACCCCAGAGGCTGGCTTCCGCC
GGAAAAACGAGCGAGGCCTCGTAG

Upstream 100 bases:

>100_bases
CTCAATCGTCCCAGTGGACAAGCGCCTGTAGTGATAAGTAGCCGATGGCGAACGCACGCTCAGTTATGTTAATGGTGGCG
TACAGCCATCAGGTCTCCCC

Downstream 100 bases:

>100_bases
CGCAGGCCGGGGGACCGGTCCTTGGAAAGCAGGAGCGGTCCGTCCAGATCAACGAAATCCGCACCCTGGGCGAGGAGGAC
CGCAGGCGCCATGGCGAGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MIPSSAPAFVAGPPPRHFALRIALLFSAPLIVNGFAMPYFPVWLSSLSLSDFEIGIVLAVPMFVRVITAPLAGVLADRIG
ERSIVLIWSGVLSFAAAIILFHAQRFWPVLVIYTLQSAVYSPYMPIVEAIALSGVRRWGFDYAQMRVWGSVAFIGATMLG
GWLIGIVGGQMVLPAMAAGFALAILLAVAAPRVGRPRRPSPITAITEPPPQSLRQTDLQLLLVGVTLINSSHAMLFAFSA
IYWQHIGYSGTQIGVLWSAGVAAEVLMFFFAKAIVRRFSVWTMIFSGCLLAVIRWLIFPMDLGFSGYFVLQCFHAFTYAI
MHTGMQHKLVERVAEEQEASAQGLYFFYTGVFTAIFTFLSGYFYAWFGVDGFYSMSVVALSGCLFTFLGWFLQPQRLASA
GKTSEAS

Sequences:

>Translated_407_residues
MIPSSAPAFVAGPPPRHFALRIALLFSAPLIVNGFAMPYFPVWLSSLSLSDFEIGIVLAVPMFVRVITAPLAGVLADRIG
ERSIVLIWSGVLSFAAAIILFHAQRFWPVLVIYTLQSAVYSPYMPIVEAIALSGVRRWGFDYAQMRVWGSVAFIGATMLG
GWLIGIVGGQMVLPAMAAGFALAILLAVAAPRVGRPRRPSPITAITEPPPQSLRQTDLQLLLVGVTLINSSHAMLFAFSA
IYWQHIGYSGTQIGVLWSAGVAAEVLMFFFAKAIVRRFSVWTMIFSGCLLAVIRWLIFPMDLGFSGYFVLQCFHAFTYAI
MHTGMQHKLVERVAEEQEASAQGLYFFYTGVFTAIFTFLSGYFYAWFGVDGFYSMSVVALSGCLFTFLGWFLQPQRLASA
GKTSEAS
>Mature_407_residues
MIPSSAPAFVAGPPPRHFALRIALLFSAPLIVNGFAMPYFPVWLSSLSLSDFEIGIVLAVPMFVRVITAPLAGVLADRIG
ERSIVLIWSGVLSFAAAIILFHAQRFWPVLVIYTLQSAVYSPYMPIVEAIALSGVRRWGFDYAQMRVWGSVAFIGATMLG
GWLIGIVGGQMVLPAMAAGFALAILLAVAAPRVGRPRRPSPITAITEPPPQSLRQTDLQLLLVGVTLINSSHAMLFAFSA
IYWQHIGYSGTQIGVLWSAGVAAEVLMFFFAKAIVRRFSVWTMIFSGCLLAVIRWLIFPMDLGFSGYFVLQCFHAFTYAI
MHTGMQHKLVERVAEEQEASAQGLYFFYTGVFTAIFTFLSGYFYAWFGVDGFYSMSVVALSGCLFTFLGWFLQPQRLASA
GKTSEAS

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=359, Percent_Identity=28.4122562674095, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44631; Mature: 44631

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSSAPAFVAGPPPRHFALRIALLFSAPLIVNGFAMPYFPVWLSSLSLSDFEIGIVLAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHH
PMFVRVITAPLAGVLADRIGERSIVLIWSGVLSFAAAIILFHAQRFWPVLVIYTLQSAVY
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPYMPIVEAIALSGVRRWGFDYAQMRVWGSVAFIGATMLGGWLIGIVGGQMVLPAMAAGF
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALAILLAVAAPRVGRPRRPSPITAITEPPPQSLRQTDLQLLLVGVTLINSSHAMLFAFSA
HHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IYWQHIGYSGTQIGVLWSAGVAAEVLMFFFAKAIVRRFSVWTMIFSGCLLAVIRWLIFPM
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGFSGYFVLQCFHAFTYAIMHTGMQHKLVERVAEEQEASAQGLYFFYTGVFTAIFTFLS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GYFYAWFGVDGFYSMSVVALSGCLFTFLGWFLQPQRLASAGKTSEAS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MIPSSAPAFVAGPPPRHFALRIALLFSAPLIVNGFAMPYFPVWLSSLSLSDFEIGIVLAV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHH
PMFVRVITAPLAGVLADRIGERSIVLIWSGVLSFAAAIILFHAQRFWPVLVIYTLQSAVY
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SPYMPIVEAIALSGVRRWGFDYAQMRVWGSVAFIGATMLGGWLIGIVGGQMVLPAMAAGF
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ALAILLAVAAPRVGRPRRPSPITAITEPPPQSLRQTDLQLLLVGVTLINSSHAMLFAFSA
HHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IYWQHIGYSGTQIGVLWSAGVAAEVLMFFFAKAIVRRFSVWTMIFSGCLLAVIRWLIFPM
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGFSGYFVLQCFHAFTYAIMHTGMQHKLVERVAEEQEASAQGLYFFYTGVFTAIFTFLS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GYFYAWFGVDGFYSMSVVALSGCLFTFLGWFLQPQRLASAGKTSEAS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]