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The map label for this gene is moaC [H]

Identifier: 150396624

GI number: 150396624

Start: 1491707

End: 1492201

Strand: Direct

Name: moaC [H]

Synonym: Smed_1410

Alternate gene names: 150396624

Gene position: 1491707-1492201 (Clockwise)

Preceding gene: 150396623

Following gene: 150396625

Centisome position: 39.44

GC content: 63.23

Gene sequence:

>495_bases
ATGAGCGGGCCTGCCCTCACCCATATCGACAGCGCCGGCGAAGCGAGCATGGTCGATGTCGGCGACAAGACCGAGACGGT
CCGCGTCGCCGTCGCGGAGGGCTTCGTCAGGATGAAGCCGGAGACGTTGGCACTGATTCGCGAAGGAAATGCCAAGAAGG
GCGACGTTATCGCAACCGCCCGGCTCGCGGGAATAATGGCCGCCAAGCAGACATCGAGCCTCATTCCGCTCTGCCATCCA
TTGATGCTGACGAAAGTGTCGGTCGAGATTGCCCCGGATGACGCGCTCCCCGGTTTGCGGGTAGAAGCGATGGCGAAGCT
GACCGGCCGAACGGGTGTCGAAATGGAAGCACTGACTGCCGTCAGCGTCGCCTGCCTTACGATCTACGACATGGCCAAGG
CCGCGGACCGGGACATGGAAATCGGCGGGGTGCGGCTGGTCAGTAAATCGGGCGGGCGTTCCGGCGACTATCGTCGCGAG
GGAGACATGCGCTGA

Upstream 100 bases:

>100_bases
CCACCTTCCTGGTCGGTGAAAGCCTGATGAGGAAGGACGACGTCGAGGCGGCAACGCGTGCGCTGCTGACCGGCTCCGCA
AACATTCTGGCGGCAGAGTG

Downstream 100 bases:

>100_bases
TGTCGCTTCTTTCGGTCGAGGAGGCGCTGAAGAGAATTTTGGCAAAAGCGCGACCGCCGCAACGGGTGGAACGCGTGGCG
CTCCATGATTGCCTCGGGCG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSGPALTHIDSAGEASMVDVGDKTETVRVAVAEGFVRMKPETLALIREGNAKKGDVIATARLAGIMAAKQTSSLIPLCHP
LMLTKVSVEIAPDDALPGLRVEAMAKLTGRTGVEMEALTAVSVACLTIYDMAKAADRDMEIGGVRLVSKSGGRSGDYRRE
GDMR

Sequences:

>Translated_164_residues
MSGPALTHIDSAGEASMVDVGDKTETVRVAVAEGFVRMKPETLALIREGNAKKGDVIATARLAGIMAAKQTSSLIPLCHP
LMLTKVSVEIAPDDALPGLRVEAMAKLTGRTGVEMEALTAVSVACLTIYDMAKAADRDMEIGGVRLVSKSGGRSGDYRRE
GDMR
>Mature_163_residues
SGPALTHIDSAGEASMVDVGDKTETVRVAVAEGFVRMKPETLALIREGNAKKGDVIATARLAGIMAAKQTSSLIPLCHPL
MLTKVSVEIAPDDALPGLRVEAMAKLTGRTGVEMEALTAVSVACLTIYDMAKAADRDMEIGGVRLVSKSGGRSGDYRREG
DMR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=157, Percent_Identity=63.0573248407643, Blast_Score=196, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.9664429530201, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=50.9677419354839, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=50.6944444444444, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17259; Mature: 17128

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPALTHIDSAGEASMVDVGDKTETVRVAVAEGFVRMKPETLALIREGNAKKGDVIATA
CCCCCCEEECCCCCCEEEECCCCCCEEEEEEECCEEEECCHHEEEEECCCCCCCCEEEHH
RLAGIMAAKQTSSLIPLCHPLMLTKVSVEIAPDDALPGLRVEAMAKLTGRTGVEMEALTA
HHHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
VSVACLTIYDMAKAADRDMEIGGVRLVSKSGGRSGDYRREGDMR
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGPALTHIDSAGEASMVDVGDKTETVRVAVAEGFVRMKPETLALIREGNAKKGDVIATA
CCCCCEEECCCCCCEEEECCCCCCEEEEEEECCEEEECCHHEEEEECCCCCCCCEEEHH
RLAGIMAAKQTSSLIPLCHPLMLTKVSVEIAPDDALPGLRVEAMAKLTGRTGVEMEALTA
HHHHHHHHHCCCCCCHHHHHHEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
VSVACLTIYDMAKAADRDMEIGGVRLVSKSGGRSGDYRREGDMR
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]